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Immunology

D-Index
65
Citations
15261
World Ranking
2847
National Ranking
188

Overview

Sven Brandau is affiliated with the University of Duisburg-Essen in Germany and has an extensive research portfolio primarily within the fields of immunology, microbiology, medicine, biochemistry, genetics, and molecular biology. Their scholarly contributions span multiple subfields, including immunology, molecular biology, oncology, genetics, and cancer research, reflecting a broad and interdisciplinary research focus.

Their research topics broadly encompass areas such as:

  • Immune cells in cancer
  • Neutrophil, myeloperoxidase and oxidative mechanisms
  • Immune cell function and interaction
  • Immune response and inflammation
  • Extracellular vesicles in disease
  • Mesenchymal stem cell research
  • Inflammatory biomarkers in disease prognosis

Several recent papers illustrate the scope and depth of their work, including:

  • Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation (2020, Journal for ImmunoTherapy of Cancer)
  • N1 versus N2 and PMN-MDSC: A critical appraisal of current concepts on tumor-associated neutrophils and new directions for human oncology (2022, Immunological Reviews)
  • Inflammation-driven activation of JAK/STAT signaling reversibly accelerates acute myeloid leukemia in vitro (2020, Blood Advances)
  • Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model (2023, Cytotherapy)
  • Immunological priming of mesenchymal stromal/stem cells and their extracellular vesicles augments their therapeutic benefits in experimental graft-versus-host disease via engagement of PD-1 ligands (2023, Frontiers in Immunology)

Frequent publication venues for Sven Brandau include:

  • Laryngo-Rhino-Otologie
  • Cytotherapy
  • Frontiers in Immunology
  • HNO
  • Journal for ImmunoTherapy of Cancer

Their collaboration network features several frequent coauthors, notably:

  • Kirsten Bruderek
  • Stephan Lang
  • Peter A. Horn
  • Timon Hussain
  • Simon F. Merz

In addition to journal articles, Sven Brandau has contributed to book literature, including a publication titled Myeloid-Derived Suppressor Cells released by Springer Science+Business Media in 2020.

Best Publications

  • Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

    Vincenzo Bronte;Sven Brandau;Shu Hsia Chen;Mario P. Colombo

  • Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

    Claudia A. Dumitru;Katrin Moses;Sokratis Trellakis;Stephan Lang

  • Type I IFNs induce anti‐tumor polarization of tumor associated neutrophils in mice and human

    Lisa Andzinski;Nadine Kasnitz;Stephanie Stahnke;Ching-Fang Wu

  • Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties

    Sven Brandau;Sokratis Trellakis;Kirsten Bruderek;Dominik Schmaltz

  • Immune Mechanisms in Bacillus Calmette-Guerin Immunotherapy for Superficial Bladder Cancer

    Andreas Böhle;Sven Brandau

  • Modulation of neutrophil granulocytes in the tumor microenvironment: mechanisms and consequences for tumor progression.

    Claudia A. Dumitru;Stephan Lang;Sven Brandau

  • Human neutrophils: Their role in cancer and relation to myeloid-derived suppressor cells.

    Katrin Moses;Sven Brandau

  • Polymorphonuclear granulocytes in human head and neck cancer: enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease.

    Sokratis Trellakis;Kirsten Bruderek;Claudia A. Dumitru;Hossein Gholaman

  • Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.

    Anja Hasenberg;Mike Hasenberg;Linda Männ;Franziska Neumann

  • Neutrophil granulocytes are required for effective Bacillus Calmette-Guérin immunotherapy of bladder cancer and orchestrate local immune responses

    Henrik Suttmann;Josef Riemensberger;Gabriele Bentien;Dominik Schmaltz

  • NK cells are essential for effective BCG immunotherapy

    Sven Brandau;Josef Riemensberger;Marc Jacobsen;Don Kemp

  • Thirty Years of BCG Immunotherapy for Non-Muscle Invasive Bladder Cancer: A Success Story With Room for Improvement

    Sven Brandau;Henrik Suttmann

  • PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer

    Benjamin A. Kansy;Benjamin A. Kansy;Fernando Concha-Benavente;Raghvendra M. Srivastava;Hyun Bae Jie

  • Clinical Relevance and Suppressive Capacity of Human Myeloid-Derived Suppressor Cell Subsets.

    Stephan Lang;Kirsten Bruderek;Cordelia Kaspar;Benedikt Höing

  • Toward harmonized phenotyping of human myeloid-derived suppressor cells by flow cytometry: results from an interim study

    Susanna Mandruzzato;Sven Brandau;Cedrik M. Britten;Cedrik M. Britten;Vincenzo Bronte

  • Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice

    Aly S;Wagner K;Keller C;Malm S

  • Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates

    Luca Cassetta;Espen Sønderaal Bækkevold;Sven Brandau;Anna Bujko

  • Genetically Determined Susceptibility to Tuberculosis in Mice Causally Involves Accelerated and Enhanced Recruitment of Granulocytes

    Christine Keller;Reinhard Hoffmann;Roland Lang;Sven Brandau

  • Interferon-γ and Tumor Necrosis Factor-α Differentially Affect Cytokine Expression and Migration Properties of Mesenchymal Stem Cells

    Hatim Hemeda;Mark Jakob;Anna-Kristin Ludwig;Bernd Giebel

  • The kinship of neutrophils and granulocytic myeloid-derived suppressor cells in cancer: cousins, siblings or twins?

    Sven Brandau;Katrin Moses;Stephan Lang

  • Tissue-resident mesenchymal stem cells attract peripheral blood neutrophils and enhance their inflammatory activity in response to microbial challenge.

    Sven Brandau;Mark Jakob;Mark Jakob;Hatim Hemeda;Kirsten Bruderek

Frequent Co-Authors

Christopher Barner-Kowollik
Christopher Barner-Kowollik Queensland University of Technology
Matthias Gunzer
Matthias Gunzer University of Duisburg-Essen
Matthias Epple
Matthias Epple University of Duisburg-Essen
Torsten Goldmann
Torsten Goldmann Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Bernd Giebel
Bernd Giebel University of Duisburg-Essen
Theresa L. Whiteside
Theresa L. Whiteside University of Pittsburgh
Robert L. Ferris
Robert L. Ferris University of Pittsburgh
Jan Buer
Jan Buer University of Duisburg-Essen
Viktor Umansky
Viktor Umansky Heidelberg University
Yu Lei
Yu Lei Sun Yat-sen University

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