World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
12950
World Ranking
10309
National Ranking
745

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

The scientist’s investigation covers issues in Cell biology, Signal transducing adaptor protein, T-cell receptor, Signal transduction and Molecular biology. He studies Phosphorylation, a branch of Cell biology. His Signal transducing adaptor protein research is multidisciplinary, incorporating perspectives in Intracellular signalling, Signalling and Transmembrane protein.

His biological study spans a wide range of topics, including Receptor, Adaptor Signaling Protein, B-cell receptor and Metabolism. His work on Rap1 and Small GTPase as part of his general Signal transduction study is frequently connected to Membrane protein, thereby bridging the divide between different branches of science. His research investigates the connection between Molecular biology and topics such as CD3 that intersect with issues in Monoclonal antibody, Cell surface receptor and T lymphocyte.

His most cited work include:

  • Shp2 Regulates Src Family Kinase Activity and Ras/Erk Activation by Controlling Csk Recruitment (362 citations)
  • A Logical Model Provides Insights into T Cell Receptor Signaling (277 citations)
  • Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling. (193 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cell biology, T cell, T-cell receptor, Signal transducing adaptor protein and Signal transduction. His Cell biology research integrates issues from Integrin, Immune system and Transmembrane protein. His T cell research is multidisciplinary, incorporating elements of Molecular biology and CD3.

His T-cell receptor research incorporates elements of Receptor, Cancer research, Apoptosis and MAPK/ERK pathway. His research investigates the connection between Signal transducing adaptor protein and topics such as Cell activation that intersect with problems in Linker for Activation of T cells. His work in Phosphorylation tackles topics such as Tyrosine kinase which are related to areas like Tyrosine.

He most often published in these fields:

  • Cell biology (62.72%)
  • T cell (31.36%)
  • T-cell receptor (24.85%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (62.72%)
  • T cell (31.36%)
  • Immune system (18.34%)

In recent papers he was focusing on the following fields of study:

Cell biology, T cell, Immune system, Immunology and T-cell receptor are his primary areas of study. His studies deal with areas such as Jurkat cells and Integrin as well as Cell biology. His T cell research incorporates themes from Molecular biology, Apoptosis and Proto-oncogene tyrosine-protein kinase Src.

Burkhart Schraven combines subjects such as Excitotoxicity, Cell and Cytokine with his study of Immune system. His work carried out in the field of T-cell receptor brings together such families of science as Reactive oxygen species and Cytokine secretion. His Signal transduction research is multidisciplinary, incorporating elements of Experimental autoimmune encephalomyelitis and Antigen.

Between 2013 and 2021, his most popular works were:

  • Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke. (117 citations)
  • Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes. (115 citations)
  • T cells and reactive oxygen species (111 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

His primary scientific interests are in Cell biology, Immune system, T cell, Acquired immune system and T-cell receptor. His specific area of interest is Cell biology, where Burkhart Schraven studies Cell adhesion molecule. The various areas that Burkhart Schraven examines in his Immune system study include Cell, Infiltration, Pathology, Microglia and Receptor.

His studies in T cell integrate themes in fields like Methylglyoxal, Cell growth, Tyrosine kinase, CD8 and Immunotherapy. His Tyrosine kinase study combines topics from a wide range of disciplines, such as CD28, Jurkat cells, ZAP70 and Phosphorylation. The study incorporates disciplines such as Apoptosis and Signal transduction in addition to T-cell receptor.

Best Publications

  • Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

    Tomás̆ Brdic̆ka;Dagmar Pavlis̆tová;Albrecht Leo;Eddy Bruyns

  • Shp2 Regulates Src Family Kinase Activity and Ras/Erk Activation by Controlling Csk Recruitment

    Si Qing Zhang;Wentian Yang;Maria I. Kontaridis;Trever G. Bivona

  • A Logical Model Provides Insights into T Cell Receptor Signaling

    Julio Saez-Rodriguez;Luca Simeoni;Jonathan A. Lindquist;Rebecca Hemenway

  • CD45 in human physiology and clinical medicine

    Andreas Rheinländer;Burkhart Schraven;Ursula Bommhardt

  • Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.

    Anja Hasenberg;Mike Hasenberg;Linda Männ;Franziska Neumann

  • Transmembrane adaptor proteins: organizers of immunoreceptor signalling

    Václav Ho rcaron;ejší;Weiguo Zhang;Burkhart Schraven

  • Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling.

    Tomáš Brdička;Martin Imrich;Pavla Angelisová;Naděžda Brdičková

  • Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.

    Jens Neumann;Monika Riek-Burchardt;Monika Riek-Burchardt;Josephine Herz;Thorsten R. Doeppner

  • T cells and reactive oxygen species

    Aleksey V. Belikov;Burkhart Schraven;Luca Simeoni

  • G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands.

    Anja Köhler;Katia De Filippo;Mike Hasenberg;Cindy van den Brandt

  • Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal.

    Tobias Baumann;Andreas Dunkel;Christian Schmid;Sabine Schmitt

  • The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages.

    Deborah S. Black;Anne Marie-Cardine;Burkhart Schraven;James B. Bliska

  • T Cell Receptor (TCR) Interacting Molecule (TRIM), A Novel Disulfide-linked Dimer Associated with the TCR–CD3–ζ Complex, Recruits Intracellular Signaling Proteins to the Plasma Membrane

    Eddy Bruyns;Anne Marie-Cardine;Henning Kirchgessner;Karin Sagolla

  • Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts.

    Knut Martin Torgersen;Torkel Vang;Hilde Abrahamsen;Sheraz Yaqub

  • The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1.

    Stefanie Kliche;Dennis Breitling;Mauro Togni;Rico Pusch

  • RIAM Links the ADAP/SKAP-55 Signaling Module to Rap1, Facilitating T-Cell-Receptor-Mediated Integrin Activation

    Gaël Ménasché;Stefanie Kliche;Emily J. H. Chen;Theresia E. B. Stradal

  • LIME A New Membrane Raft-associated Adaptor Protein Involved in CD4 and CD8 Coreceptor Signaling

    Naděžda Brdičková;Tomáš Brdička;Pavla Angelisová;Ondrej Horváth

  • Mechanisms of Opioid-Mediated Inhibition of Human T Cell Receptor Signaling

    Christine Börner;Beate Warnick;Michal Smida;Roland Hartig

  • Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytes.

    Anne Marie-Cardine;Eddy Bruyns;Christoph Eckerskorn;Henning Kirchgessner

  • A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56lck and pp32, a possible common substrate.

    Burkhart Schraven;Henning Kirchgessner;Brigitte Gaber;Yvonne Samstag

Frequent Co-Authors

Dirk Reinhold
Dirk Reinhold Otto-von-Guericke University Magdeburg
Stefan Meuer
Stefan Meuer Heidelberg University
Matthias Gunzer
Matthias Gunzer University of Duisburg-Essen
Vaclav Horejsi
Vaclav Horejsi Czech Academy of Sciences
Jürgen Wienands
Jürgen Wienands University of Göttingen
Harald Gollnick
Harald Gollnick Otto-von-Guericke University Magdeburg
Wolfgang W. A. Schamel
Wolfgang W. A. Schamel University of Freiburg
Gary A. Koretzky
Gary A. Koretzky Cornell University
Klaus Neubert
Klaus Neubert Martin Luther University Halle-Wittenberg
Marie Malissen
Marie Malissen Aix-Marseille University

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