D-Index & Metrics Best Publications

Vaclav Horejsi

Czech Academy of Sciences
Czech Republic

Biology and Biochemistry

2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Biology and Biochemistry D-index 69 Citations 14,576 198 World Ranking 4746 National Ranking 4

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Czech Republic Leader Award

2022 - Research.com Biology and Biochemistry in Czech Republic Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

Gene
Enzyme
Immune system

Vaclav Horejsi spends much of his time researching Biochemistry, T cell, Molecular biology, Cell biology and Major histocompatibility complex. His Biochemistry study combines topics from a wide range of disciplines, such as Antibody and Antigen. He works on T cell which deals in particular with Jurkat cells.

His work deals with themes such as Tyrosine-protein kinase CSK and Phosphorylation, Tyrosine phosphorylation, which intersect with Jurkat cells. His study focuses on the intersection of Molecular biology and fields such as Signal transducing adaptor protein with connections in the field of COS cells and Tyrosine kinase. He interconnects Linker for Activation of T cells and T-cell receptor in the investigation of issues within Cell biology.

His most cited work include:

GPI-anchored cell-surface molecules complexed to protein tyrosine kinases. (739 citations)
Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation (412 citations)
Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation (412 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Molecular biology, Biochemistry, Antigen and Monoclonal antibody. His research in Cell biology tackles topics such as Transmembrane protein which are related to areas like Transmembrane domain and Kinase. The Molecular biology study combines topics in areas such as T cell, Cell culture, Human leukocyte antigen and COS cells.

The various areas that he examines in his Antigen study include Cellular differentiation, Antibody, CD antigen and Peptide sequence. His studies deal with areas such as Epitope, Intracellular, Blot and Virology as well as Monoclonal antibody. Vaclav Horejsi specializes in Phosphorylation, namely Proto-oncogene tyrosine-protein kinase Src.

He most often published in these fields:

Cell biology (47.73%)
Molecular biology (27.27%)
Biochemistry (24.24%)

What were the highlights of his more recent work (between 2008-2019)?

Cell biology (47.73%)
Transmembrane protein (12.88%)
Signal transducing adaptor protein (14.39%)

In recent papers he was focusing on the following fields of study:

Cell biology, Transmembrane protein, Signal transducing adaptor protein, Signal transduction and Lipid raft are his primary areas of study. His Cell biology research is multidisciplinary, incorporating perspectives in T cell and T-cell receptor. His Thymocyte, ZAP70 and Jurkat cells study in the realm of T cell connects with subjects such as Lipid phosphorylation.

His Signal transducing adaptor protein research focuses on Transmembrane domain and how it relates to Cytoplasmic part, 14-3-3 protein, Integral membrane protein and Caveolae. His Lipid raft research incorporates elements of SH3 domain, Tetraspanin and Membrane protein. His study on Proto-oncogene tyrosine-protein kinase Src is covered under Biochemistry.

Between 2008 and 2019, his most popular works were:

CD nomenclature 2015: Human leukocyte differentiation antigen workshops as a driving force in immunology (62 citations)
SCIMP, a Transmembrane Adaptor Protein Involved in Major Histocompatibility Complex Class II Signaling (41 citations)
Membrane microdomains in immunoreceptor signaling (37 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

GPI-anchored cell-surface molecules complexed to protein tyrosine kinases.

Irena Stefanova;Vaclav Horejsi;Ignacio J. Ansotegui;Walter Knapp.
Science (1991)

1022 Citations

Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

Tomás̆ Brdic̆ka;Dagmar Pavlis̆tová;Albrecht Leo;Eddy Bruyns.
Journal of Experimental Medicine (2000)

636 Citations

Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes.

J Bohuslav;V Horejsí;C Hansmann;J Stöckl.
Journal of Experimental Medicine (1995)

445 Citations

The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases

T Cinek;V Horejsí.
Journal of Immunology (1992)

363 Citations

Biochemical characterization of a soluble form of the 53-kDa monocyte surface antigen

V Bazil;V Horejsí;M Baudys;H Kristofová.
European Journal of Immunology (1986)

298 Citations

Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY.

J. Szollosi;V.L Horejsi;L. Bene;P. Angelisova.
Journal of Immunology (1996)

286 Citations

Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line.

J C Gorga;V Horejsí;D R Johnson;R Raghupathy.
Journal of Biological Chemistry (1987)

281 Citations

Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling.

Tomáš Brdička;Martin Imrich;Pavla Angelisová;Naděžda Brdičková.
Journal of Experimental Medicine (2002)

266 Citations

Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes.

H Kropshofer;H Kropshofer;S Spindeldreher;T A Röhn;N Platania.
Nature Immunology (2002)

260 Citations

Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor.

Dominique Davidson;Marcin Bakinowski;Matthew L. Thomas;Vaclav Horejsi.
Molecular and Cellular Biology (2003)

242 Citations

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Frequent Co-Authors

External Links

Personal Website for Vaclav Horejsi