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Immunology
Czechia
2026
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Biology and Biochemistry
Czechia
2025

D-Index & Metrics

Immunology

D-Index
71
Citations
16238
World Ranking
2339
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Immunology in Czechia Leader Award
  • 2025 - Research.com Biology and Biochemistry in Czechia Leader Award
  • 2023 - Research.com Biology and Biochemistry in Czechia Leader Award
  • 2022 - Research.com Biology and Biochemistry in Czechia Leader Award

Overview

Vaclav Horejsi is affiliated with the Czech Academy of Sciences in the Czech Republic. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a strong focus on Molecular Biology, Oncology, Immunology, Biomedical Engineering, and Electrical and Electronic Engineering as subfields.

Their scientific contributions include investigations into lipid membrane structure and behavior, CAR-T cell therapy research, RNA interference and gene delivery, cancer immunotherapy and biomarkers, immunotherapy and immune responses, membrane-based ion separation techniques, and fuel cells and related materials.

Some of the notable recent publications by Vaclav Horejsi include:

  • UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells (2020, OncoImmunology)
  • Sulfonated polystyrenes: pH and Mg2+-insensitive amphiphilic copolymers for detergent-free membrane protein isolation (2023, European Polymer Journal)
  • Targeting CD10 on B-Cell Leukemia Using the Universal CAR T-Cell Platform (UniCAR) (2022, International Journal of Molecular Sciences)
  • Composition of raft-like cell membrane microdomains resistant to styrene-maleic acid copolymer (SMA) solubilization (2023, Biophysical Chemistry)
  • Tailoring Butyl Methacrylate/Methacrylic Acid Copolymers for the Solubilization of Membrane Proteins: The Influence of Composition and Molecular Weight (2022, Macromolecular Bioscience)

Vaclav Horejsi regularly publishes in a variety of scientific journals, including:

  • OncoImmunology
  • European Polymer Journal
  • International Journal of Molecular Sciences
  • Biophysical Chemistry
  • Macromolecular Bioscience

Frequent collaborators in their research include Pavla Angelisová, Claudia Arndt, Liliana R. Loureiro, Anja Feldmann, and Ralf Bergmann.

Best Publications

  • GPI-anchored cell-surface molecules complexed to protein tyrosine kinases.

    Irena Stefanova;Vaclav Horejsi;Ignacio J. Ansotegui;Walter Knapp

  • Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

    Tomás̆ Brdic̆ka;Dagmar Pavlis̆tová;Albrecht Leo;Eddy Bruyns

  • Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes.

    J Bohuslav;V Horejsí;C Hansmann;J Stöckl

  • The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases

    T Cinek;V Horejsí

  • GPI-microdomains: a role in signalling via immunoreceptors

    Václav Hořejšı́;Karel Drbal;Marek Cebecauer;Marek Cebecauer;Jan Černý;Jan Černý

  • Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY.

    J. Szollosi;V.L Horejsi;L. Bene;P. Angelisova

  • Biochemical characterization of a soluble form of the 53-kDa monocyte surface antigen

    V Bazil;V Horejsí;M Baudys;H Kristofová

  • Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line.

    J C Gorga;V Horejsí;D R Johnson;R Raghupathy

  • Transmembrane adaptor proteins: organizers of immunoreceptor signalling

    Václav Ho rcaron;ejší;Weiguo Zhang;Burkhart Schraven

  • Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling.

    Tomáš Brdička;Martin Imrich;Pavla Angelisová;Naděžda Brdičková

  • Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes.

    H Kropshofer;H Kropshofer;S Spindeldreher;T A Röhn;N Platania

  • Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor.

    Dominique Davidson;Marcin Bakinowski;Matthew L. Thomas;Vaclav Horejsi

  • Disulfide bond-mediated dimerization of HLA-G on the cell surface

    Jonathan E. Boyson;Robert Erskine;Mary C. Whitman;Michael Chiu

  • Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins.

    P Angelisová;I Hilgert;V Horejsí

  • Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation.

    Stéphanie Coupel;Anne Moreau;Mohamed Hamidou;Vaclav Horejsi

  • LAT Displacement from Lipid Rafts as a Molecular Mechanism for the Inhibition of T Cell Signaling by Polyunsaturated Fatty Acids

    Maximilian Zeyda;Gunther Staffler;Vaclav Horejsi;Werner Waldhausl

  • M6P/IGFII‐receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor‐β1

    Samuel Godár;Václav Hořejší;Ulrich H. Weidle;Bernd R. Binder

  • CD molecules 2005: human cell differentiation molecules

    Heddy Zola;Bernadette Swart;Ian Nicholson;Bent Aasted

  • The roles of membrane microdomains (rafts) in T cell activation.

    Václav Hor̆ejs̆í

  • Structural relationship between the soluble and membrane-bound forms of human monocyte surface glycoprotein CD14.

    Vladimír Bažil;Miroslav Baudyš;Ivan Hilgert;Irena Štefanová

Frequent Co-Authors

Burkhart Schraven
Burkhart Schraven Otto-von-Guericke University Magdeburg
Hannes Stockinger
Hannes Stockinger Medical University of Vienna
Bernard Malissen
Bernard Malissen Aix-Marseille University
Daniel G. Tenen
Daniel G. Tenen National University of Singapore
Armand Bensussan
Armand Bensussan Hôpital Saint-Louis
Christopher D. Buckley
Christopher D. Buckley University of Oxford
Mariagrazia Uguccioni
Mariagrazia Uguccioni Universita della Svizzera Italiana
James H. Morrissey
James H. Morrissey University of Michigan–Ann Arbor
Curt I. Civin
Curt I. Civin University of Maryland, Baltimore
Marie Malissen
Marie Malissen Aix-Marseille University

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