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Maria José Alcaraz

Maria José Alcaraz

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
20967
World Ranking
14757
National Ranking
315

Overview

Maria José Alcaraz is affiliated with the University of Valencia in Spain and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology and rheumatology. Their work covers several intersecting areas related to extracellular vesicles, osteoarthritis treatment, and disease regulation by microRNAs and circular RNAs.

The scientist has authored multiple papers on the roles and mechanisms of extracellular vesicles in disease, particularly relating to osteoarthritis and rheumatoid arthritis. Some notable recent publications include:

  • Role of peroxiredoxin 6 in the chondroprotective effects of microvesicles from human adipose tissue-derived mesenchymal stem cells, 2021, Journal of Orthopaedic Translation
  • New potential therapeutic approaches targeting synovial fibroblasts in rheumatoid arthritis, 2021, Biochemical Pharmacology
  • Osteostatin Inhibits M-CSF+RANKL-Induced Human Osteoclast Differentiation by Modulating NFATc1, 2022, International Journal of Molecular Sciences
  • Extracellular Vesicles Do Not Mediate the Anti-Inflammatory Actions of Mouse-Derived Adipose Tissue Mesenchymal Stem Cells Secretome, 2021, International Journal of Molecular Sciences
  • Control of articular degeneration by extracellular vesicles from stem/stromal cells as a potential strategy for the treatment of osteoarthritis, 2024, Biochemical Pharmacology

Their work also spans research on inflammatory pathways and cellular differentiation, with a particular emphasis on conditions like rheumatoid arthritis and osteoarthritis.

Frequent co-authors in their research include:

  • María Isabel Guillén
  • Marı́a Luisa Ferrándiz
  • María Carmen Terencio
  • María Carmen Carceller
  • Miguel Tofiño-Vian

The primary publication venues for the scientist's work are:

  • Biochemical Pharmacology
  • International Journal of Molecular Sciences
  • Journal of Orthopaedic Translation
  • Stem Cells Translational Medicine
  • Methods in molecular biology

The main fields of study for Maria José Alcaraz include biochemistry, genetics and molecular biology, and medicine, while selected subfields cover molecular biology, rheumatology, cancer research, oncology, and surgery.

The frequent research topics explored by the scientist are:

  • Extracellular vesicles in disease
  • Osteoarthritis treatment and mechanisms
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Knee injuries and reconstruction techniques
  • Rheumatoid arthritis research and therapies
  • Signaling pathways in disease

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

    Antonio Cuadrado;Gina Manda;Ahmed Hassan;María José Alcaraz

  • Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation.

    A. Mora;M. Payá;J.L. Ríos;M.J. Alcaraz

  • Anti-Inflammatory Actions of the Heme Oxygenase-1 Pathway

    M. J. Alcaraz;P. Fernandez;M. I. Guillen

  • Co-regulation between cyclo-oxygenase-2 and inducible nitric oxide synthase expression in the time-course of murine inflammation.

    I. Posadas;M.C. Terencio;I. Guillén;M.L. Ferrándiz

  • Microvesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells as a New Protective Strategy in Osteoarthritic Chondrocytes.

    Miguel Tofiño-Vian;Maria Isabel Guillén;María Dolores Pérez Del Caz;Antonio Silvestre

  • New molecular targets for the treatment of osteoarthritis.

    Maria José Alcaraz;Javier Megías;Isabel García-Arnandis;Victoria Clérigues

  • Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

    Sergio Portal-Núñez;Pedro Esbrit;María José Alcaraz;Raquel Largo

  • Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Downregulate Senescence Features in Osteoarthritic Osteoblasts.

    Miguel Tofiño-Vian;Maria Isabel Guillén;María Dolores Pérez del Caz;Miguel Angel Castejón

  • The carbon monoxide‐releasing molecule CORM‐2 inhibits the inflammatory response induced by cytokines in Caco‐2 cells

    J Megías;J Busserolles;M J Alcaraz

  • Current perspectives on parathyroid hormone (PTH) and PTH-related protein (PTHrP) as bone anabolic therapies.

    Pedro Esbrit;María José Alcaraz;María José Alcaraz

  • High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes

    Isabel García-Arnandis;Maria Isabel Guillén;Francisco Gomar;Jean-Pierre Pelletier

  • Effects of petrosaspongiolide M, a novel phospholipase A2 inhibitor, on acute and chronic inflammation.

    Garcia-Pastor P;Randazzo A;Gomez-Paloma L;Alcaraz Mj

  • Deficiency of Nrf2 accelerates the effector phase of arthritis and aggravates joint disease

    Nuria Maicas;María Luisa Ferrándiz;Rita Brines;Lidia Ibáñez

  • Heme oxygenase-1 inhibits apoptosis in Caco-2 cells via activation of Akt pathway.

    Jérôme Busserolles;Javier Megías;María Carmen Terencio;María José Alcaraz

  • Anti-inflammatory and joint protective effects of extra-virgin olive-oil polyphenol extract in experimental arthritis☆

    María Ángeles Rosillo;María José Alcaraz;Marina Sánchez-Hidalgo;José G. Fernández-Bolaños

  • Effects of Nrf2 Deficiency on Bone Microarchitecture in an Experimental Model of Osteoporosis

    Lidia Ibáñez;María Luisa Ferrándiz;Rita Brines;David Guede

  • Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2.

    Carolina P. Reyes;Marvin J. Núñez;Ignacio A. Jiménez;Jérôme Busserolles

  • Role of nuclear factor‐κB and heme oxygenase‐1 in the mechanism of action of an anti‐inflammatory chalcone derivative in RAW 264.7 cells

    María José Alcaraz;Ana María Vicente;Amparo Araico;José N Dominguez

  • Influence of anti-inflammatory flavonoids on degranulation and arachidonic acid release in rat neutrophils.

    María Tordera;María Luisa Ferrándiz;María José Alcaraz

Frequent Co-Authors

Antonio Cuadrado
Antonio Cuadrado Autonomous University of Madrid
Wim B. van den Berg
Wim B. van den Berg Radboud University
Antonio Randazzo
Antonio Randazzo University of Naples Federico II
Marije I. Koenders
Marije I. Koenders Radboud University
Hossein Baharvand
Hossein Baharvand Royan Institute
Jacques Maclouf
Jacques Maclouf Lariboisière Hospital
Edit I. Buzás
Edit I. Buzás Semmelweis University
Thomas Kislinger
Thomas Kislinger University of Toronto
Christophe Créminon
Christophe Créminon Centre national de la recherche scientifique, CNRS
Ramón Martínez-Máñez
Ramón Martínez-Máñez Universitat Politècnica de València

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