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Immunology

D-Index
44
Citations
5677
World Ranking
4809
National Ranking
2158

Overview

C. Henrique Serezani is affiliated with Vanderbilt University Medical Center in the United States and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research spans multiple specialized subfields including Immunology, Molecular Biology, Epidemiology, Infectious Diseases, and Physiology.

Their scientific investigations focus on key topics such as Immune Response and Inflammation, Immune cells in cancer, Antimicrobial Resistance in Staphylococcus, Inflammasome and immune disorders, Phagocytosis and Immune Regulation, Immune Cell Function and Interaction, and Adipokines, Inflammation, and Metabolic Diseases.

The list of recent papers authored or co-authored by Serezani includes the following:

  • Obesity induces PD-1 on macrophages to suppress anti-tumour immunity, 2024, Nature
  • Streptococcus agalactiae cadD alleviates metal stress and promotes intracellular survival in macrophages and ascending infection during pregnancy, 2022, Nature Communications
  • STAT4 is expressed in neutrophils and promotes antimicrobial immunity, 2021, JCI Insight
  • LTB4-Driven Inflammation and Increased Expression of ALOX5/ACE2 During Severe COVID-19 in Individuals With Diabetes, 2021, Diabetes
  • Leukotriene B 4 licenses inflammasome activation to enhance skin host defense, 2020, Proceedings of the National Academy of Sciences

Their frequent co-authors include Amondrea Blackman, Ana Carolina Guerta Salina, Nathan Klopfenstein, Alexandra Ivo de Medeiros, and Eden E Faneuff.

Serezani publishes regularly in several scientific venues, with a notable frequency in:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • ImmunoHorizons
  • Journal of Investigative Dermatology
  • Nature

Best Publications

  • Cyclic AMP: master regulator of innate immune cell function.

    Carlos H. Serezani;Megan N. Ballinger;David M. Aronoff;Marc Peters-Golden

  • Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1.

    David M. Aronoff;Claudio Canetti;Carlos H. Serezani;Carlos H. Serezani;Ming Luo

  • Prostaglandin E2 Suppresses Bacterial Killing in Alveolar Macrophages by Inhibiting NADPH Oxidase

    Carlos H. Serezani;Jooho Chung;Megan N. Ballinger;Bethany B. Moore

  • Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling

    Alexandra I. Medeiros;Carlos H. Serezani;Sang Pyo Lee;Sang Pyo Lee;Marc Peters-Golden

  • Differential Stem and Progenitor Cell Trafficking by Prostaglandin E2

    Jonathan Hoggatt;Khalid S. Mohammad;Pratibha Singh;Amber F. Hoggatt;Amber F. Hoggatt

  • Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase

    Carlos H. C. Serezani;David M. Aronoff;David M. Aronoff;Sonia Jancar;Sonia Jancar;Peter Mancuso;Peter Mancuso

  • MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation.

    Zhuo Wang;Stephanie Brandt;Alexandra Medeiros;Soujuan Wang

  • Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression

    Carlos H. Serezani;Casey Lewis;Sonia Jancar;Marc Peters-Golden

  • Role of granulocyte macrophage colony-stimulating factor during gram-negative lung infection with Pseudomonas aeruginosa.

    Megan N. Ballinger;Robert Paine;Carlos H. C. Serezani;David M. Aronoff

  • Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality

    Karina F. Zoccal;Carlos A. Sorgi;Juliana I. Hori;Francisco W. G. Paula-Silva

  • Leukotrienes are essential for the control of Leishmania amazonensis infection and contribute to strain variation in susceptibility.

    Carlos Henrique Serezani;Carlos Henrique Serezani;Joao H. Perrela;Momtchilo Russo;Marc Peters-Golden

  • Synthetic Prostacyclin Analogs Differentially Regulate Macrophage Function via Distinct Analog-Receptor Binding Specificities

    David M. Aronoff;Camila M. Peres;Camila M. Peres;Carlos H. Serezani;Megan N. Ballinger

  • Prostaglandin E 2 and the Suppression of Phagocyte Innate Immune Responses in Different Organs

    Alexandra Ivo de Medeiros;Camila Peres-Buzalaf;Felipe Fortino Verdan;C. Henrique Serezani

  • The Class A Scavenger Receptor, Macrophage Receptor with Collagenous Structure, Is the Major Phagocytic Receptor for Clostridium sordellii Expressed by Human Decidual Macrophages

    Tennille Thelen;Yibai Hao;Alexandra I. Medeiros;Jeffrey L. Curtis

  • Outer Surface Protein OspC Is an Antiphagocytic Factor That Protects Borrelia burgdorferi from Phagocytosis by Macrophages

    Sebastian E. Carrasco;Bryan Troxell;Youyun Yang;Stephanie L. Brandt

  • PPAR-γ/IL-10 Axis Inhibits MyD88 Expression and Ameliorates Murine Polymicrobial Sepsis

    Ana Elisa Ferreira;Flavia Sisti;Flavia Sisti;Fabiane Sônego;Suojuan Wang

  • Misoprostol Impairs Female Reproductive Tract Innate Immunity against Clostridium sordellii

    David M. Aronoff;Yibai Hao;Jooho Chung;Nicole Coleman

  • Distinct protein kinase A anchoring proteins direct prostaglandin E2 modulation of Toll-like receptor signaling in alveolar macrophages.

    Sang Hoon Kim;Carlos Henrique Serezani;Katsuhide Okunishi;Zbigniew Zaslona

  • Innate Immunity to Staphylococcus aureus: Evolving Paradigms in Soft Tissue and Invasive Infections.

    Stephanie L. Brandt;Stephanie L. Brandt;Nicole E. Putnam;James E. Cassat;C. Henrique Serezani;C. Henrique Serezani

  • Specific leukotriene receptors couple to distinct G proteins to effect stimulation of alveolar macrophage host defense functions.

    Camila M. Peres;David M. Aronoff;Carlos H. Serezani;Nicolas Flamand

  • Murine Colitis is Mediated by Vimentin

    Nirit Mor-Vaknin;Maureen Legendre;Yue Yu;Carlos H. C. Serezani

  • Leukotriene B4 Enhances the Generation of Proinflammatory MicroRNAs To Promote MyD88-Dependent Macrophage Activation

    Zhuo Wang;Luciano Ribeiro Filgueiras;Luciano Ribeiro Filgueiras;Soujuan Wang;Ana Paula Moreira Serezani

  • FcγRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions

    Carlos H. Serezani;David M. Aronoff;Robert G. Sitrin;Marc Peters-Golden

Frequent Co-Authors

José C. Alves-Filho
José C. Alves-Filho Universidade de São Paulo
Marc Peters-Golden
Marc Peters-Golden University of Michigan–Ann Arbor
Fernando Q. Cunha
Fernando Q. Cunha Universidade de São Paulo
David L. Morris
David L. Morris University of New South Wales
Matthias Gunzer
Matthias Gunzer University of Duisburg-Essen
Hector R. Wong
Hector R. Wong Cincinnati Children's Hospital Medical Center
Reuben Kapur
Reuben Kapur Indiana University
Charles S. Dela Cruz
Charles S. Dela Cruz Yale University
Jeffrey C. Rathmell
Jeffrey C. Rathmell Vanderbilt University Medical Center
Bethany B. Moore
Bethany B. Moore University of Michigan–Ann Arbor

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