Laurence C. Eisenlohr

Overview

Best Publications

• The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

  Teresa Fernandes-Alnemri;Je-Wook Yu;Je-Wook Yu;Christine Juliana;Leobaldo Solorzano

  848
  Citations

• Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

  Norbert Pardi;Michael J. Hogan;Martin S. Naradikian;Kaela Parkhouse

  485
  Citations

• Intratumoral recombinant GM-CSF-encoding virus as gene therapy in patients with cutaneous melanoma.

  Michael J Mastrangelo;Henry C Maguire;Laurence C Eisenlohr;Carol E Laughlin

  436
  Citations

• SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation.

  Katlyn Lederer;Diana Castaño;Diana Castaño;Daniela Gómez Atria;Thomas H. Oguin

  374
  Citations

• A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice.

  Dorottya Laczkó;Michael J. Hogan;Sushila A. Toulmin;Philip Hicks

  368
  Citations

• Antigen processing in vivo and the elicitation of primary CTL responses.

  Nicholas P. Restifo;Igor Bačík;Kari R. Irvine;Jonathan W. Yewdell

  279
  Citations

• Impaired Assembly yet Normal Trafficking of MHC Class I Molecules in Tapasin Mutant Mice

  Andres G Grandea;Tatiana N Golovina;Sara E Hamilton;Venkataraman Sriram

  271
  Citations

• Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes.

  L C Eisenlohr;J W Yewdell;J R Bennink

  258
  Citations

• MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL.

  Y Deng;J W Yewdell;L C Eisenlohr;J R Bennink

  258
  Citations

• The Immunogenicity of a New Human Minor Histocompatibility Antigen Results from Differential Antigen Processing

  Anthony G. Brickner;Edus H. Warren;Edus H. Warren;Jennifer A. Caldwell;Yoshiki Akatsuka;Yoshiki Akatsuka

  242
  Citations

• The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained.

  Wherry Ej;Puorro Ka;Porgador A;Eisenlohr Lc

  228
  Citations

• Antigen presentation requires transport of MHC class I molecules from the endoplasmic reticulum.

  Josephine H. Cox;Jonathan W. Yewdell;Laurence C. Eisenlohr;Philip R. Johnson

  218
  Citations

• A cytosolic pathway for MHC class II–restricted antigen processing that is proteasome and TAP dependent

  Mona K Tewari;Gomathinayagam Sinnathamby;Deepa Rajagopal;Laurence C Eisenlohr

  193
  Citations

• The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein.

  R. A. Pierce;E. D. Field;T. Mutis;T. N. Golovina

  173
  Citations

• The adenovirus capsid protein hexon contains a highly conserved human CD4+ T-cell epitope

  Melanie Olive;Laurence Eisenlohr;Neal Flomenberg;Susan Hsu

  153
  Citations

• Dependence of Both Spontaneous and Antibody-Dependent, Granule Exocytosis-Mediated NK Cell Cytotoxicity on Extracellular Signal-Regulated Kinases

  Rossana Trotta;Kristin A. Puorro;Marino Paroli;Livio Azzoni

  146
  Citations

• The minor histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein.

  Eric Spierings;Anthony G. Brickner;Jennifer A. Caldwell;Suzanne Zegveld

  141
  Citations

• STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury

  Andrew J. Paris;Katharina E. Hayer;Joseph H. Oved;Daphne C. Avgousti

  135
  Citations

• Ribosomal scanning past the primary initiation codon as a mechanism for expression of CTL epitopes encoded in alternative reading frames.

  T. N. J. Bullock;L. C. Eisenlohr

  131
  Citations

• Generation of CD8+ T Cell Memory in Response to Low, High, and Excessive Levels of Epitope

  E. John Wherry;Michael J. McElhaugh;Laurence C. Eisenlohr

  120
  Citations

• Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein.

  A J Yellen-Shaw;E J Wherry;G C Dubois;L C Eisenlohr

  114
  Citations