His scientific interests lie mostly in Biochemistry, Enzyme, Amino acid, Proteasome and Stereochemistry. His Biochemistry research is multidisciplinary, incorporating perspectives in Kidney and Multicatalytic proteinase. His biological study spans a wide range of topics, including Proteasome endopeptidase complex and Mechanism of action.
His work carried out in the field of Amino acid brings together such families of science as Prolyl endopeptidase and Substrate. His studies in Proteasome integrate themes in fields like Cancer research, Intracellular, Cell growth and Proteolysis. His Stereochemistry research integrates issues from Metalloendopeptidase, Peptide and Enzyme inhibitor.
Biochemistry, Enzyme, Amino acid, Stereochemistry and Metalloendopeptidase are his primary areas of study. He usually deals with Biochemistry and limits it to topics linked to Molecular biology and Endoplasmic reticulum. Marian Orlowski has included themes like Carboxylate, Hydrolysis and Sodium dodecyl sulfate in his Enzyme study.
His Amino acid research is multidisciplinary, incorporating perspectives in Chromatography and Carboxylic acid. The Stereochemistry study combines topics in areas such as Proline, Residue, Enzyme kinetics, Active site and Peptide. His studies deal with areas such as Thermolysin, Endocrinology, Internal medicine and Thimet oligopeptidase as well as Metalloendopeptidase.
Marian Orlowski mainly investigates Biochemistry, Proteasome, Amino acid, Branched-chain amino acid and Proteolysis. His Biochemistry study incorporates themes from Spleen and Antigen. His Proteasome study integrates concerns from other disciplines, such as Residue, Cancer research and Cell growth.
The concepts of his Amino acid study are interwoven with issues in Cleavage, Stereochemistry and Substrate. The various areas that he examines in his Stereochemistry study include Proline, Cleave and Aldehyde. His Proteolysis research is multidisciplinary, incorporating elements of Enzyme activator and Intracellular.
Marian Orlowski mainly focuses on Proteasome, Biochemistry, Proteolysis, Enzyme activator and Ubiquitin-conjugating enzyme. His Proteasome research is multidisciplinary, relying on both Cancer research, Cell growth, Multiple myeloma and Drug resistance. His research in Cancer research intersects with topics in In vitro, Hematology, Internal medicine, Immunology and Bortezomib.
His works in Amino acid, Sodium dodecyl sulfate, Cleave, Serine and Enzyme are all subjects of inquiry into Biochemistry. His work is dedicated to discovering how Proteolysis, Cell biology are connected with Metabolism, Proteases and Residue and other disciplines. His Enzyme activator study combines topics in areas such as Unfolded protein response, Endoplasmic-reticulum-associated protein degradation and Lactacystin.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
The multicatalytic proteinase complex, a major extralysosomal proteolytic system.
The γ-Glutamyl Cycle: A Possible Transport System for Amino Acids
Marian Orlowski;Alton Meister.
Proceedings of the National Academy of Sciences of the United States of America (1970)
Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids.
Marian Orlowski;Christopher Cardozo;Charlene Michaud.
Evidence that Pituitary Cation‐Sensitive Neutral Endopeptidase Is a Multicatalytic Protease Complex
Sherwin Wilk;Marian Orlowski.
Journal of Neurochemistry (1983)
Cation-Sensitive Neutral Endopeptidase: Isolation and Specificity of the Bovine Pituitary Enzyme
Sherwin Wilk;Marian Orlowski.
Journal of Neurochemistry (1980)
Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor
Robert Z. Orlowski;Jairam R. Eswara;Anne Lafond-Walker;Michael R. Grever.
Cancer Research (1998)
CD4 Glycoprotein Degradation Induced by Human Immunodeficiency Virus Type 1 Vpu Protein Requires the Function of Proteasomes and the Ubiquitin-Conjugating Pathway
Ulrich Schubert;Luis C. Antón;Igor Bačík;Josephine H. Cox.
Journal of Virology (1998)
Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex.
Marian Orlowski;Sherwin Wilk.
Archives of Biochemistry and Biophysics (2000)
γ -Glutamyl Transpeptidase in Brain Capillaries: Possible Site of a Blood-Brain Barrier for Amino Acids
Marian Orlowski;Grazia Sessa;Jack Peter Green.
A soluble metalloendopeptidase from rat brain
Marian Orlowski;Charlene Michaud;Thomas G. Chu.
FEBS Journal (1983)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: