What is he best known for?
The fields of study he is best known for:
- Enzyme
- Amino acid
- Biochemistry
His scientific interests lie mostly in Biochemistry, Enzyme, Amino acid, Proteasome and Stereochemistry.
His Biochemistry research is multidisciplinary, incorporating perspectives in Kidney and Multicatalytic proteinase.
His biological study spans a wide range of topics, including Proteasome endopeptidase complex and Mechanism of action.
His work carried out in the field of Amino acid brings together such families of science as Prolyl endopeptidase and Substrate.
His studies in Proteasome integrate themes in fields like Cancer research, Intracellular, Cell growth and Proteolysis.
His Stereochemistry research integrates issues from Metalloendopeptidase, Peptide and Enzyme inhibitor.
His most cited work include:
- The multicatalytic proteinase complex, a major extralysosomal proteolytic system. (423 citations)
- The γ-Glutamyl Cycle: A Possible Transport System for Amino Acids (413 citations)
- Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. (310 citations)
What are the main themes of his work throughout his whole career to date?
Biochemistry, Enzyme, Amino acid, Stereochemistry and Metalloendopeptidase are his primary areas of study.
He usually deals with Biochemistry and limits it to topics linked to Molecular biology and Endoplasmic reticulum.
Marian Orlowski has included themes like Carboxylate, Hydrolysis and Sodium dodecyl sulfate in his Enzyme study.
His Amino acid research is multidisciplinary, incorporating perspectives in Chromatography and Carboxylic acid.
The Stereochemistry study combines topics in areas such as Proline, Residue, Enzyme kinetics, Active site and Peptide.
His studies deal with areas such as Thermolysin, Endocrinology, Internal medicine and Thimet oligopeptidase as well as Metalloendopeptidase.
He most often published in these fields:
- Biochemistry (64.65%)
- Enzyme (41.41%)
- Amino acid (33.33%)
What were the highlights of his more recent work (between 1992-2009)?
- Biochemistry (64.65%)
- Proteasome (18.18%)
- Amino acid (33.33%)
In recent papers he was focusing on the following fields of study:
Marian Orlowski mainly investigates Biochemistry, Proteasome, Amino acid, Branched-chain amino acid and Proteolysis.
His Biochemistry study incorporates themes from Spleen and Antigen.
His Proteasome study integrates concerns from other disciplines, such as Residue, Cancer research and Cell growth.
The concepts of his Amino acid study are interwoven with issues in Cleavage, Stereochemistry and Substrate.
The various areas that he examines in his Stereochemistry study include Proline, Cleave and Aldehyde.
His Proteolysis research is multidisciplinary, incorporating elements of Enzyme activator and Intracellular.
Between 1992 and 2009, his most popular works were:
- Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. (310 citations)
- Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor (256 citations)
- CD4 Glycoprotein Degradation Induced by Human Immunodeficiency Virus Type 1 Vpu Protein Requires the Function of Proteasomes and the Ubiquitin-Conjugating Pathway (253 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Amino acid
- Biochemistry
Marian Orlowski mainly focuses on Proteasome, Biochemistry, Proteolysis, Enzyme activator and Ubiquitin-conjugating enzyme.
His Proteasome research is multidisciplinary, relying on both Cancer research, Cell growth, Multiple myeloma and Drug resistance.
His research in Cancer research intersects with topics in In vitro, Hematology, Internal medicine, Immunology and Bortezomib.
His works in Amino acid, Sodium dodecyl sulfate, Cleave, Serine and Enzyme are all subjects of inquiry into Biochemistry.
His work is dedicated to discovering how Proteolysis, Cell biology are connected with Metabolism, Proteases and Residue and other disciplines.
His Enzyme activator study combines topics in areas such as Unfolded protein response, Endoplasmic-reticulum-associated protein degradation and Lactacystin.
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