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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
27515
World Ranking
2132
National Ranking
48

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Jürgen Roth is a researcher affiliated with the University of Zurich in Switzerland, with a publication record primarily in the fields of biochemistry, genetics, and molecular biology. Their research spans over 110 publications in these main fields, including 47 in medicine. The focus on subfields highlights a concentration in molecular biology, cancer research, oncology, genetics, and immunology.

Their main topics of study encompass various biomedical themes related to cancer biology and molecular mechanisms. These include:

  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Ubiquitin and Proteasome Pathways
  • Cancer-related Molecular Pathways
  • 3D Printing in Biomedical Research
  • Mitochondrial Function and Pathology

Jürgen Roth's frequent publication venues reflect a strong presence in the journal Histochemistry and Cell Biology, with 69 publications, alongside one publication in Neurobiology of Disease. Their body of work includes a range of research articles focusing on cellular and molecular biology techniques and topics relevant to cancer and pathology.

Recent papers authored by Jürgen Roth include:

  • Histochemistry and Cell Biology-a glance into the past and a look ahead (2023), published in Histochemistry and Cell Biology

Jürgen Roth often collaborates with other researchers, most notably Douglas J. Taatjes, with whom they have co-authored 67 publications. Other frequent co-authors include Takehiko Koji, Michael Schrader, Lauren Fielding, and Marissa Menard.

Their scientific contributions reflect an interdisciplinary approach that integrates diverse aspects of cancer biology, molecular diagnostics, and innovative biomedical technologies such as 3D printing. This work supports ongoing advances in understanding cancer mechanisms and molecular pathways relevant to diagnostics and therapeutic strategies.

Best Publications

  • Ultrastructural localization of intracellular antigens by the use of protein A-gold complex.

    J Roth;M Bendayan;L Orci

  • The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver.

    Thomas Gerloff;Bruno Stieger;Bruno Hagenbuch;Jerzy Madon

  • Enhancement of structural preservation and immunocytochemical staining in low temperature embedded pancreatic tissue.

    J Roth;M Bendayan;E Carlemalm;W Villiger

  • The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins).

    Anthony W. Norman;Jürgen Roth;Lelio Orci

  • Immunocytochemical localization of galactosyltransferase in HeLa cells: codistribution with thiamine pyrophosphatase in trans-Golgi cisternae.

    J Roth;E G Berger

  • Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins

    R. Montesano;J. Roth;A. Robert;L. Orci

  • Protein N-glycosylation along the secretory pathway: relationship to organelle topography and function, protein quality control, and cell interactions.

    Jürgen Roth

  • Application of lectin--gold complexes for electron microscopic localization of glycoconjugates on thin sections.

    Jurgen Roth

  • Degradation of Misfolded Endoplasmic Reticulum Glycoproteins in Saccharomyces cerevisiae Is Determined by a Specific Oligosaccharide Structure

    Claude A. Jakob;Patricie Burda;Jürgen Roth;Markus Aebi

  • Demonstration of an extensive trans-tubular network continuous with the Golgi apparatus stack that may function in glycosylation

    Jürgen Roth;Douglas J. Taatjes;John M. Lucocq;Jasminder Weinstein

  • Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan.

    S R Carlsson;J Roth;F Piller;M Fukuda

  • Quantitative immunocytochemical localization of pancreatic secretory proteins in subcellular compartments of the rat acinar cell.

    Moise Bendayan;Jurgen Roth;Alain Perrelet;Lelio Orci

  • Subcellular organization of glycosylation in mammalian cells.

    Jürgen Roth

  • Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain.

    Christian Zuber;Peter M. Lackie;William A. Catterall;Jürgen Roth

  • Immunohistochemical mapping of calcium-binding protein immunoreactivity in the rat central nervous system

    L.M. Garcia-Segura;D. Baetens;J. Roth;A.W. Norman;A.W. Norman

  • Cytochemical localization of terminal N-acetyl-D-galactosamine residues in cellular compartments of intestinal goblet cells: implications for the topology of O-glycosylation.

    J Roth

  • Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms.

    Birgit Görtz;Jürgen Roth;Akiko Krähenmann;Ronald R. de Krijger

  • Reexpression of poly(sialic acid) units of the neural cell adhesion molecule in Wilms tumor.

    Jurgen Roth;Christian Zuber;Philipp Wagner;Douglas J. Taatjes

  • The preparation of protein A-gold complexes with 3 nm and 15 nm gold particles and their use in labelling multiple antigens on ultra-thin sections

    Jurgen Roth

  • Differential subcompartmentation of terminal glycosylation in the Golgi apparatus of intestinal absorptive and goblet cells.

    J. Roth;D. J. Taatjes;Jasminder Weinstein;J. C. Paulson

Frequent Co-Authors

Lelio Orci
Lelio Orci University of Geneva
Douglas J. Taatjes
Douglas J. Taatjes University of Vermont
John M. Lucocq
John M. Lucocq University of St Andrews
Irwin J. Goldstein
Irwin J. Goldstein University of Michigan–Ann Arbor
Tetsutaro Sata
Tetsutaro Sata National Institute of Infectious Diseases
James C. Paulson
James C. Paulson Scripps Research Institute
Anthony W. Norman
Anthony W. Norman University of California, Riverside
Moise Bendayan
Moise Bendayan University of Montreal
Aurel Perren
Aurel Perren University of Bern
Bernard Thorens
Bernard Thorens University of Lausanne

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