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Biology and Biochemistry

D-Index
74
Citations
17804
World Ranking
5657
National Ranking
2682

Overview

Martin F. Flajnik is affiliated with the University of Maryland, Baltimore in the United States. Their research primarily contributes to the field of Immunology and Microbiology, with over 40 publications. Their work spans several related subfields, including Immunology, Molecular Biology, Immunology and Allergy, Radiology, Nuclear Medicine and Imaging, and Nephrology.

Their scientific inquiries focus on various topics in immunology, particularly:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Aquaculture disease management and microbiota
  • Invertebrate Immune Response Mechanisms
  • Immune Response and Inflammation
  • Cell Adhesion Molecules Research
  • Galectins and Cancer Biology

Frequent publication venues where Martin F. Flajnik has contributed include:

  • Immunogenetics
  • The Journal of Immunology
  • European Journal of Immunology
  • Molecular Immunology
  • Frontiers in Immunology

Among their recent published works are:

  • "An Ancestral Major Histocompatibility Complex Organization in Cartilaginous Fish: Reconstructing MHC Origin and Evolution" (2023), published in Molecular Biology and Evolution
  • "From IgZ to IgT: A Call for a Common Nomenclature for Immunoglobulin Heavy Chain Genes of Ray-Finned Fish" (2021), published in Zebrafish
  • "An Ancient, MHC-Linked, Nonclassical Class I Lineage in Cartilaginous Fish" (2020), published in The Journal of Immunology
  • "Lost structural and functional inter-relationships between Ig and TCR loci in mammals revealed in sharks" (2021), published in Immunogenetics
  • "Identification of the Fc-alpha/mu receptor in Xenopus provides insight into the emergence of the poly-Ig receptor (pIgR) and mucosal Ig transport" (2021), published in European Journal of Immunology

Martin F. Flajnik collaborates frequently with several coauthors, including:

  • Yuko Ohta
  • Ana Veríssimo
  • Tereza Almeida
  • Michael F. Criscitiello
  • Antonio Muñoz-Mérida

Best Publications

  • Origin and evolution of the adaptive immune system: genetic events and selective pressures

    Martin F. Flajnik;Masanori Kasahara

  • Genome evolution in the allotetraploid frog Xenopus laevis

    Adam M. Session;Adam M. Session;Yoshinobu Uno;Taejoon Kwon;Taejoon Kwon;Jarrod A. Chapman

  • A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks

    Greenberg As;Avila D;Hughes M;Hughes A

  • Elephant shark genome provides unique insights into gnathostome evolution

    Byrappa Venkatesh;Byrappa Venkatesh;Alison P. Lee;Vydianathan Ravi;Ashish K. Maurya

  • Comparative analyses of immunoglobulin genes: surprises and portents.

    Martin F. Flajnik

  • Comparative genomics of the MHC: glimpses into the evolution of the adaptive immune system.

    Martin F. Flajnik;Masanori Kasahara

  • Evolution of innate and adaptive immunity: can we draw a line?

    Martin F. Flajnik;Louis Du Pasquier

  • Crystal Structure of a Shark Single-Domain Antibody V Region in Complex with Lysozyme

    Robyn L. Stanfield;Helen Dooley;Martin F. Flajnik;Ian A. Wilson

  • THE IMMUNE SYSTEM OF XENOPUS

    L Du Pasquier;J Schwager;M F Flajnik

  • Structural analysis of the nurse shark (new) antigen receptor (NAR): molecular convergence of NAR and unusual mammalian immunoglobulins.

    K H Roux;A S Greenberg;L Greene;L Strelets

  • A cold-blooded view of adaptive immunity.

    Martin F. Flajnik

  • The Translesion DNA Polymerase ζ Plays a Major Role in Ig and bcl-6 Somatic Hypermutation

    Hong Zan;Atsumasa Komori;Zongdong Li;Andrea Cerutti

  • IgD, like IgM, is a primordial immunoglobulin class perpetuated in most jawed vertebrates

    Yuko Ohta;Martin Flajnik

  • Selection and characterization of naturally occurring single-domain (IgNAR) antibody fragments from immunized sharks by phage display

    H. Dooley;M. F. Flajnik;Andrew Justin Radcliffe Porter

  • Antibody repertoire development in cartilaginous fish

    H. Dooley;M.F. Flajnik

  • Primitive synteny of vertebrate major histocompatibility complex class I and class II genes.

    Yuko Ohta;Kazuhiko Okamura;E. Churchill McKinney;Simona Bartl

  • Evolutionary conservation of MHC class I and class II molecules--different yet the same.

    Jim Kaufman;Jan Salomonsen;Martin Flajnik

  • A Case Of Convergence: Why Did a Simple Alternative to Canonical Antibodies Arise in Sharks and Camels?

    Martin F. Flajnik;Nick Deschacht;Serge Muyldermans

  • Shark immunity bites back: affinity maturation and memory response in the nurse shark, Ginglymostoma cirratum

    Helen Dooley;Martin F Flajnik

  • Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase ζ

    Marilyn Diaz;Laurent K. Verkoczy;Martin F. Flajnik;Norman R. Klinman

Frequent Co-Authors

Masanori Kasahara
Masanori Kasahara Hokkaido University
Louis Du Pasquier
Louis Du Pasquier University of Basel
Andrew S. Greenberg
Andrew S. Greenberg Tufts University
Masaru Nonaka
Masaru Nonaka University of Tokyo
James C. Kaufman
James C. Kaufman University of Connecticut
Byrappa Venkatesh
Byrappa Venkatesh Agency for Science, Technology and Research
Tomas Marques-Bonet
Tomas Marques-Bonet Pompeu Fabra University
Wesley C. Warren
Wesley C. Warren University of Missouri
Thomas Boehm
Thomas Boehm Max Planck Society
Robyn L. Stanfield
Robyn L. Stanfield Scripps Research Institute

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