World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
83
Citations
19458
World Ranking
1475
National Ranking
743

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Paolo Casali is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research primarily focuses on immunology and microbiology, accumulating 63 publications in this field. Additionally, their work spans medicine with 18 related publications. Casali's subfields of study include immunology, oncology, cancer research, epidemiology, and molecular biology.

The scientist's work extensively covers topics such as immune cell function and interaction, T-cell and B-cell immunology, immunotherapy and immune responses, cytomegalovirus and herpesvirus research, IL-33, ST2, and ILC pathways, cancer-related molecular mechanisms, and microRNA in disease regulation.

Casali has contributed to numerous research papers published in various venues. Frequent publication outlets include:

  • The Journal of Immunology (17 publications)
  • Nature Communications (3 publications)
  • Science Advances (3 publications)
  • Nature Immunology (2 publications)
  • Frontiers in Immunology (2 publications)

Select recent papers by Paolo Casali include:

  • "B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids," 2020, Nature Communications
  • "B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response," 2020, Science Advances
  • "Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells," 2020, Nature Communications
  • "A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses," 2024, Nature Immunology
  • "Estrogen Reverses HDAC Inhibitor-Mediated Repression of Aicda and Class-Switching in Antibody and Autoantibody Responses by Downregulation of miR-26a," 2020, Frontiers in Immunology

Casali has collaborated frequently with several researchers, including:

  • Hong Zan
  • Zhenming Xu
  • Daniel P. Chupp
  • Justin B. Moroney
  • Carlos Eduardo Rivera

The scientist received recognition as a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

    Mikhail B. Litinskiy;Bernardetta Nardelli;David M. Hilbert;Bing He

  • Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

    Guillermina Girardi;Jessica Berman;Patricia Redecha;Lynn Spruce

  • Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset

    Paolo Casali;Samuele .E Burastero;Minoru Nakamura;Giorgio Inghirami

  • CD5+ B lymphocytes, polyreactive antibodies and the human B-cell repertoire

    Paolo Casali;Abner L. Notkins

  • Immunoglobulin class-switch DNA recombination: induction, targeting and beyond

    Zhenming Xu;Hong Zan;Egest J. Pone;Thach Mai

  • The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement.

    Bernard Chang;Paolo Casali

  • Nature and functions of autoantibodies

    Keith Elkon;Paolo Casali

  • Probing the human B-cell repertoire with EBV: polyreactive antibodies and CD5+ B lymphocytes.

    P Casali;A L Notkins

  • ANTIPHOSPHOLIPID ANTIBODIES AFFECT TROPHOBLAST GONADOTROPIN SECRETION AND INVASIVENESS BY BINDING DIRECTLY AND THROUGH ADHERED β2-GLYCOPROTEIN I

    N Di Simone;P L Meroni;N Del Papa;E Raschi

  • Structure and Function of Natural Antibodies

    P. Casali;E. W. Schettino

  • B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids.

    Helia N. Sanchez;Justin B. Moroney;Huoqun Gan;Huoqun Gan;Tian Shen;Tian Shen

  • Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis.

    S E Burastero;P Casali;R L Wilder;A L Notkins

  • BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway

    Egest J Pone;Jinsong Zhang;Jinsong Zhang;Thach Mai;Clayton A White

  • EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching.

    Bing He;Nancy Raab-Traub;Paolo Casali;Andrea Cerutti

  • Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families.

    I Sanz;P Casali;J W Thomas;A L Notkins

  • Reduced tetanus antibody titers in overweight children

    Alon Eliakim;Christina Schwindt;Frank Zaldivar;Paolo Casali

  • 160 h of chemical-looping combustion in a 10 kW reactor system with a NiO-based oxygen carrier

    Unknown

  • The Translesion DNA Polymerase ζ Plays a Major Role in Ig and bcl-6 Somatic Hypermutation

    Hong Zan;Atsumasa Komori;Zongdong Li;Andrea Cerutti

  • The response of wire rope strands to axial tensile loads—Part I. Experimental results and theoretical predictions

    Unknown

  • Analysis of the structural correlates for antibody polyreactivity by multiple reassortments of chimeric human immunoglobulin heavy and light chain V segments.

    Yuji Ichiyoshi;Paolo Casali

Frequent Co-Authors

Abner Louis Notkins
Abner Louis Notkins National Institutes of Health
Andrea Cerutti
Andrea Cerutti Icahn School of Medicine at Mount Sinai
Jinsong Zhang
Jinsong Zhang Chinese Academy of Sciences
Maria E. Fernandez
Maria E. Fernandez The University of Texas Health Science Center at Houston
Daniel M. Knowles
Daniel M. Knowles Cornell University
Giorgio Inghirami
Giorgio Inghirami Cornell University
Ronald L. Wilder
Ronald L. Wilder National Institutes of Health
Haian Fu
Haian Fu Emory University
Félix A. Rey
Félix A. Rey Institut Pasteur
Rick A. Wetsel
Rick A. Wetsel The University of Texas Health Science Center at Houston

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