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Microbiology

D-Index
74
Citations
28934
World Ranking
1537
National Ranking
671

Overview

Alexander Khoruts is a researcher affiliated with the University of Minnesota in the United States. Their work spans several areas within medicine and biochemistry, genetics, and molecular biology, with a strong emphasis on infectious diseases and hepatology.

The scientist's research focuses extensively on topics related to gut microbiota, gastrointestinal disorders, and liver diseases. Key areas of study include:

  • Clostridium difficile and Clostridium perfringens research
  • Gut microbiota and health
  • Gastrointestinal motility and disorders
  • Liver Disease and Transplantation
  • Microscopic Colitis
  • Neutropenia and Cancer Infections
  • Liver Disease Diagnosis and Treatment

Khoruts has contributed to at least 187 publications in the field of medicine and 70 in biochemistry, genetics, and molecular biology. Their subfields of expertise include infectious diseases (60 publications), molecular biology (54 publications), epidemiology (30 publications), hepatology (18 publications), and oncology (18 publications).

Alexander Khoruts has published articles in several prominent scientific venues. The most frequent publications appear in:

  • Gastroenterology (19 papers)
  • Gut Microbes (10 papers)
  • Journal of Hepatology (5 papers)
  • The American Journal of Gastroenterology (5 papers)
  • Blood (5 papers)

Some of the recent papers authored or coauthored by Khoruts include:

  • "Microbiota-Driven Activation of Intrahepatic B Cells Aggravates NASH Through Innate and Adaptive Signaling," 2021, Hepatology
  • "Microbiota changes and intestinal microbiota transplantation in liver diseases and cirrhosis," 2020, Journal of Hepatology
  • "Faecal microbiota transplantation for Clostridioides difficile: mechanisms and pharmacology," 2020, Nature Reviews Gastroenterology & Hepatology
  • "Interactions between the gut microbiome and host gene regulation in cystic fibrosis," 2020, Genome Medicine
  • "Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β," 2020, Immunity

Frequent collaborators in their research include:

  • Christopher Staley
  • Armin Rashidi
  • Shernan G. Holtan
  • Daniel J. Weisdorf
  • Byron P. Vaughn

Best Publications

  • CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract

    Jason M. Brenchley;Timothy W. Schacker;Laura E. Ruff;David A. Price

  • Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

    Dae Wook Kang;James B. Adams;Ann C. Gregory;Ann C. Gregory;Thomas Borody

  • Treating Clostridium difficile Infection With Fecal Microbiota Transplantation

    Johan S. Bakken;Thomas Borody;Lawrence J. Brandt;Joel V. Brill

  • Visualizing the generation of memory CD4 T cells in the whole body

    R. Lee Reinhardt;Alexander Khoruts;Rebecca Merica;Traci Zell

  • Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection.

    Matthew J Hamilton;Alexa R Weingarden;Michael J Sadowsky;Alexander Khoruts

  • Fecal microbiota transplantation and emerging applications

    Thomas J. Borody;Alexander Khoruts

  • Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent clostridium difficile-associated diarrhea

    Alexander Khoruts;Johan Dicksved;Janet K. Jansson;Michael J. Sadowsky

  • Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

    Jason M. Brenchley;Mirko Paiardini;Kenneth S. Knox;Kenneth S. Knox;Ava I. Asher

  • Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

    Courtney V. Fletcher;Kathryn Staskus;Stephen W. Wietgrefe;Meghan Rothenberger

  • Fecal Microbiota Transplant for Treatment of Clostridium difficile Infection in Immunocompromised Patients

    Colleen R. Kelly;Chioma Ihunnah;Monika Fischer;Alexander Khoruts

  • In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells

    Elizabeth Ingulli;Anna Mondino;Alexander Khoruts;Marc K. Jenkins

  • In Vivo Activation of Antigen-Specific CD4 T Cells

    Marc K. Jenkins;Alexander Khoruts;Elizabeth Ingulli;Daniel L. Mueller

  • Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients

    Alexander Khoruts;Laura Stahnke;Craig J. McClain;George Logan

  • Effect of Fecal Microbiota Transplantation on Recurrence in Multiply Recurrent Clostridium difficile Infection: A Randomized Trial.

    Colleen R. Kelly;Alexander Khoruts;Christopher Staley;Michael J. Sadowsky

  • Generation of Anergic and Potentially Immunoregulatory CD25+CD4 T Cells In Vivo After Induction of Peripheral Tolerance with Intravenous or Oral Antigen

    Kristen M. Thorstenson;Alexander Khoruts

  • Interaction of gut microbiota with bile acid metabolism and its influence on disease states.

    Christopher Staley;Alexa R. Weingarden;Alexander Khoruts;Michael J. Sadowsky

  • Understanding the mechanisms of faecal microbiota transplantation

    Alexander Khoruts;Michael J. Sadowsky

  • Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection

    Alexa R. Weingarden;Chi Chen;Aleh Bobr;Dana Yao

  • Naive and memory CD4+ T cell survival controlled by clonal abundance.

    Jason Hataye;James J. Moon;Alexander Khoruts;Cavan Reilly

  • Defining total-body AIDS-virus burden with implications for curative strategies

    Jacob D. Estes;Cissy Kityo;Francis Ssali;Louise Swainson

  • High-throughput DNA sequence analysis reveals stable engraftment of gut microbiota following transplantation of previously frozen fecal bacteria

    Matthew J. Hamilton;Alexa R. Weingarden;Tatsuya Unno;Alexander Khoruts

Frequent Co-Authors

Michael J. Sadowsky
Michael J. Sadowsky University of Minnesota
Daniel J. Weisdorf
Daniel J. Weisdorf University of Minnesota
Marc K. Jenkins
Marc K. Jenkins University of Minnesota
Dan Knights
Dan Knights University of Minnesota
Timothy W. Schacker
Timothy W. Schacker University of Minnesota
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Rob Knight
Rob Knight University of California, San Diego
Daniel C. Douek
Daniel C. Douek National Institute of Allergy and Infectious Diseases
Stephen C. Jameson
Stephen C. Jameson University of Minnesota
Cavan S. Reilly
Cavan S. Reilly University of Minnesota

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Related Online Degrees & Career Pathways

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