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Immunology

D-Index
75
Citations
30476
World Ranking
1950
National Ranking
955

Medicine

D-Index
75
Citations
30481
World Ranking
18986
National Ranking
9462

Overview

Timothy W. Schacker is affiliated with the University of Minnesota in the United States and focuses on medical research with a particular emphasis on infectious diseases, virology, immunology, and epidemiology. Their work spans multiple specialized fields, including emergency medicine.

Their research contributions encompass a range of topics, notably in:

  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • HIV Research and Treatment
  • HIV/AIDS Research and Interventions
  • SARS-CoV-2 detection and testing
  • HIV-related health complications and treatments
  • Immune Cell Function and Interaction

They have authored numerous publications that have appeared frequently in journals such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Infectious Diseases
  • Nature Communications
  • Journal of Virology
  • SSRN Electronic Journal

Among the recent papers are:

  • "Understanding the renin-angiotensin-aldosterone-SARS-CoV axis: a comprehensive review", 2020, European Respiratory Journal
  • "Antihypertensive drugs and risk of COVID-19?", 2020, The Lancet Respiratory Medicine
  • "High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines", 2021, Cell Reports
  • "Abundant HIV-infected cells in blood and tissues are rapidly cleared upon ART initiation during acute HIV infection", 2020, Science Translational Medicine
  • "Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial", 2022, Nature Medicine

Collaboration has been a consistent component of their work. Frequent co-authors include:

  • Jodi Anderson
  • Jeffrey G. Chipman
  • Christopher J. Tignanelli
  • Ashley T. Haase
  • Tyler D. Bold

Best Publications

  • Microbial translocation is a cause of systemic immune activation in chronic HIV infection

    Jason M. Brenchley;David A. Price;Timothy W. Schacker;Tedi E. Asher

  • CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract

    Jason M. Brenchley;Timothy W. Schacker;Laura E. Ruff;David A. Price

  • HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

    Nicolas Chomont;Mohamed El-Far;Petronela Ancuta;Lydie Trautmann

  • Clinical and epidemiologic features of primary HIV infection.

    Timothy W Schacker;Ann C. Collier;James Hughes;Theresa Shea

  • Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells.

    Z. Q. Zhang;T. Schuler;M. Zupancic;Stephen W Wietgrefe

  • PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection.

    Constantinos Petrovas;Joseph P. Casazza;Jason M. Brenchley;David A. Price

  • Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

    Jason M. Brenchley;Mirko Paiardini;Kenneth S. Knox;Kenneth S. Knox;Ava I. Asher

  • Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus type 1 infection.

    L Musey;J Hughes;T Schacker;T Shea

  • Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

    Courtney V. Fletcher;Kathryn Staskus;Stephen W. Wietgrefe;Meghan Rothenberger

  • Persistent HIV-1 replication maintains the tissue reservoir during therapy

    Ramon Lorenzo-Redondo;Helen R. Fryer;Trevor Bedford;Eun Young Kim

  • Mucosal shedding of human herpesvirus 8 in men.

    John Pauk;Meei Li Huang;Scott J. Brodie;Anna Wald

  • CXCR5 + follicular cytotoxic T cells control viral infection in B cell follicles

    Yew Ann Leong;Yaping Chen;Hong Sheng Ong;Di Wu

  • Frequent Recovery of HIV-1 From Genital Herpes Simplex Virus Lesions in HIV-1–Infected Men

    Timothy Schacker;Alexander J. Ryncarz;James Goddard;Kurt Diem

  • Defining total-body AIDS-virus burden with implications for curative strategies

    Jacob D. Estes;Cissy Kityo;Francis Ssali;Louise Swainson

  • Biological and virologic characteristics of primary HIV infection.

    Timothy W. Schacker;James P. Hughes;Theresa Shea;Robert W. Coombs

  • Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis

    Timothy W Schacker;Phuong L. Nguyen;Gregory J Beilman;Steven Wolinsky

  • Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

    Ming Zeng;Anthony J. Smith;Stephen W. Wietgrefe;Peter J. Southern

  • The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia

    Giuseppe Pantaleo;James F. Demarest;Timothy Schacker;Mauro Vaccarezza

  • Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption

    Meghan K Rothenberger;Brandon F. Keele;Stephen W Wietgrefe;Courtney V. Fletcher

  • Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

    Steven A. Yukl;Eli Boritz;Michael Busch;Christopher Bentsen

Frequent Co-Authors

Ashley T. Haase
Ashley T. Haase University of Minnesota
Cavan S. Reilly
Cavan S. Reilly University of Minnesota
Daniel C. Douek
Daniel C. Douek National Institute of Allergy and Infectious Diseases
Lawrence Corey
Lawrence Corey Fred Hutchinson Cancer Research Center
Jacob D. Estes
Jacob D. Estes Oregon Health & Science University
Douglas D. Richman
Douglas D. Richman University of California, San Diego
Peter J. Southern
Peter J. Southern University of Minnesota
Steven G. Deeks
Steven G. Deeks University of California, San Francisco
Alexander Khoruts
Alexander Khoruts University of Minnesota
Courtney V. Fletcher
Courtney V. Fletcher University of Nebraska Medical Center

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