Lukas C. Kühn

Overview

Best Publications

• Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

  Matthias W. Hentze;Lukas C. Kuhn

  1973
  Citations

• A stem-loop in the 3' untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm.

  Ernst W. Müllner;Lukas C. Kühn

  751
  Citations

• A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA.

  Ernst W. Müllner;Barbara Neupert;Lukas C. Kühn

  703
  Citations

• LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine.

  Grégoire Rossier;Christian Meier;Christian Bauch;Vanessa Summa

  498
  Citations

• The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence

  Alan McClelland;Lukas C. Kühn;Frank H. Ruddle

  449
  Citations

• Amino acid transport of y+L‐type by heterodimers of 4F2hc/CD98 and members of the glycoprotein‐associated amino acid transporter family

  Rahel Pfeiffer;Grégoire Rossier;Benjamin Spindler;Christian Meier

  378
  Citations

• Endocytosis of the transferrin receptor requires the cytoplasmic domain but not its phosphorylation site.

  Sylvia Rothenberger;Barry J. Iacopetta;Lukas C. Kühn

  252
  Citations

• Nuclear export of proteins : the role of nuclear retention

  Marlon S. Schmidt-Zachmann;Catherine Dargemont;Lukas C. Kühn;Erich A. Nigg

  248
  Citations

• Glycoprotein-associated amino acid exchangers: broadening the range of transport specificity

  François Verrey;Christian Meier;Grégoire Rossier;Lukas C. Kühn

  238
  Citations

• Mutational analysis of the [4Fe-4S]-cluster converting iron regulatory factor from its RNA-binding form to cytoplasmic aconitase

  H. Hirling;B.R. Henderson;L.C. Kühn

  222
  Citations

• Experimental hemochromatosis due to MHC class I HFE deficiency: Immune status and iron metabolism

  Seiamak Bahram;Susan Gilfillan;Lukas C. Kühn;Rémy Moret

  212
  Citations

• Characterization of a second RNA-binding protein in rodents with specificity for iron-responsive elements

  B R Henderson;C Seiser;L C Kühn

  206
  Citations

• Optimal sequence and structure of iron-responsive elements. Selection of RNA stem-loops with high affinity for iron regulatory factor.

  B R Henderson;E Menotti;C Bonnard;L C Kühn

  201
  Citations

• Recombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switch.

  Nicola K. Gray;Sabine Quick;Britta Goossen;Anne Constable

  196
  Citations

• Stimulation of system y(+)-like amino acid transport by the heavy chain of human 4F2 surface antigen in Xenopus laevis oocytes.

  Joan Bertran;Simona Magagnin;Andreas Werner;Daniel Markovich

  191
  Citations

• A role for the cytoplasmic domain in transferrin receptor sorting and coated pit formation during endocytosis

  Barry J. Iacopetta;Sylvia Rothenberger;Lukas C. Kühn

  183
  Citations

• Luminal heterodimeric amino acid transporter defective in cystinuria.

  Rahel Pfeiffer;Jan Loffing;Grégoire Rossier;Christian Bauch

  180
  Citations

• Destabilization of Interleukin-6 mRNA Requires a Putative RNA Stem-Loop Structure, an AU-Rich Element, and the RNA-Binding Protein AUF1

  Serge Paschoud;Afzal M. Dogar;Catherine Kuntz;Barbara Grisoni-Neupert

  172
  Citations

• Coordination of cellular iron metabolism by post-transcriptional gene regulation.

  Lukas C. Kühn;Matthias W. Hentze

  167
  Citations

• The mRNA-binding protein which controls ferritin and transferrin receptor expression is conserved during evolution

  Sylvia Rothenberger;Ernst W. Müllner;Lukas C. Kühn

  165
  Citations