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Biology and Biochemistry

D-Index
66
Citations
16976
World Ranking
8599
National Ranking
3862

Overview

Gary D. Luker is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple fields of study, primarily within medicine and biochemistry, genetics, and molecular biology. Key subfields include molecular biology, oncology, radiology, nuclear medicine and imaging, biomedical engineering, and genetics.

The scientist's work focuses on several main topics, including:

  • Cancer Cells and Metastasis
  • Radiomics and Machine Learning in Medical Imaging
  • Cellular Mechanics and Interactions
  • 3D Printing in Biomedical Research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Photoacoustic and Ultrasonic Imaging
  • Chemokine receptors and signaling

Gary D. Luker has contributed to numerous publication venues with the greatest number of works appearing in Radiology Imaging Cancer. Other frequent venues include bioRxiv (Cold Spring Harbor Laboratory), JCI Insight, Tomography, and Advanced Healthcare Materials.

Recent papers include:

  • Heterogeneous microenvironmental stiffness regulates pro-metastatic functions of breast cancer cells, 2021, Acta Biomaterialia
  • Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer, 2020, Breast Cancer Research
  • Phytochemicals inhibit migration of triple negative breast cancer cells by targeting kinase signaling, 2020, BMC Cancer
  • Aim2-mediated/IFN-β-independent regulation of gastric metaplastic lesions via CD8+ T cells, 2020, JCI Insight
  • At the Bench: Pre-clinical evidence for multiple functions of CXCR4 in cancer, 2020, Journal of Leukocyte Biology

Frequent co-authors working alongside Gary D. Luker include Kathryn E. Luker, Brock A. Humphries, Johanna M. Buschhaus, Brian D. Ross, and Thomas L. Chenevert. These collaborations have produced multiple publications over time, reflecting ongoing research partnerships.

Best Publications

  • Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy.

    Geeta Mehta;Amy Y. Hsiao;Marylou Ingram;Gary D. Luker

  • Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

    Anne Krug;Gary D. Luker;Gary D. Luker;Winfried Barchet;Winfried Barchet;David A. Leib;David A. Leib

  • CXCR4 regulates growth of both primary and metastatic breast cancer.

    Matthew C.P. Smith;Kathryn E. Luker;Joel R. Garbow;Julie L. Prior

  • CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

    Zhenhua Miao;Kathryn E. Luker;Bretton C. Summers;Rob Berahovich

  • Kinetics of regulated protein–protein interactions revealed with firefly luciferase complementation imaging in cells and living animals

    Kathryn E. Luker;Matthew C. P. Smith;Gary D. Luker;Seth T. Gammon

  • Optical Imaging: Current Applications and Future Directions

    Gary D. Luker;Kathryn E. Luker

  • Functions of CXCL12 and CXCR4 in breast cancer.

    Kathryn E. Luker;Gary D. Luker

  • Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells.

    Jonathan W. Song;Stephen P. Cavnar;Ann C. Walker;Kathryn E. Luker

  • Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling.

    Ming Luo;Li Shang;Michael D. Brooks;Evelyn Jiagge

  • Near-infrared fluorescent proteins

    Dmitry Shcherbo;Irina I Shemiakina;Anastasiya V Ryabova;Kathryn E Luker

  • Nanolitre liquid patterning in aqueous environments for spatially defined reagent delivery to mammalian cells

    H. Tavana;A. Jovic;B. Mosadegh;Q. Y. Lee

  • Applications of bioluminescence imaging to the study of infectious diseases

    Martha Hutchens;Gary D. Luker

  • Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands

    Kathryn E. Luker;Jessica M. Steele;Laura Anne Mihalko;Paramita Ray

  • CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity

    Lillian Cruz-Orengo;David W. Holman;Denise Dorsey;Liang Zhou

  • Scavenging of CXCL12 by CXCR7 Promotes Tumor Growth and Metastasis of CXCR4-positive Breast Cancer Cells

    Kathryn E. Luker;Sarah A. Lewin;Laura Anne Mihalko;Bradley T. Schmidt

  • Noninvasive imaging of protein–protein interactions in living animals

    Gary D. Luker;Vijay Sharma;Christina M. Pica;Julie L. Dahlheimer

  • Imaging 26S proteasome activity and inhibition in living mice

    Gary D Luker;Christina M Pica;Jiling Song;Kathryn E Luker

  • Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model

    Zhuo Zhang;Hiroe Shiratsuchi;Jules Lin;Guoan Chen

  • Noninvasive Bioluminescence Imaging of Herpes Simplex Virus Type 1 Infection and Therapy in Living Mice

    Gary D. Luker;J. Patrick Bardill;Julie L. Prior;Christina M. Pica

  • Novel Tat-peptide chelates for direct transduction of technetium-99m and rhenium into human cells for imaging and radiotherapy.

    Valery Polyakov;Vijay Sharma;Julie L. Dahlheimer;Christina M. Pica

Frequent Co-Authors

Shuichi Takayama
Shuichi Takayama Georgia Institute of Technology
David Piwnica-Worms
David Piwnica-Worms The University of Texas MD Anderson Cancer Center
Brian D. Ross
Brian D. Ross University of Michigan–Ann Arbor
Jennifer J. Linderman
Jennifer J. Linderman University of Michigan–Ann Arbor
David A. Leib
David A. Leib Dartmouth College
Max S. Wicha
Max S. Wicha University of Michigan–Ann Arbor
Euisik Yoon
Euisik Yoon University of Michigan–Ann Arbor
Joerg Lahann
Joerg Lahann University of Michigan–Ann Arbor
Theodore B. Norris
Theodore B. Norris University of Michigan–Ann Arbor
Bobak Mosadegh
Bobak Mosadegh Cornell University

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