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Microbiology

D-Index
55
Citations
30289
World Ranking
3762
National Ranking
1472

Overview

David A. Leib is affiliated with Dartmouth College in the United States, with a research focus primarily in the field of Medicine. Their work extensively covers subfields such as Epidemiology, Infectious Diseases, Genetics, Radiology, Nuclear Medicine and Imaging, and Molecular Biology.

The research topics David A. Leib has contributed to include the following:

  • Herpesvirus Infections and Treatments
  • Cytomegalovirus and herpesvirus research
  • Virus-based gene therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Virology and Viral Diseases
  • Mosquito-borne diseases and control
  • Viral gastroenteritis research and epidemiology

David A. Leib has published in various venues, with the most frequent publication sources being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • PLoS Pathogens
  • mBio
  • The Journal of Infectious Diseases

They have collaborated frequently with several co-authors, including:

  • Margaret E. Ackerman
  • Iara M. Backes
  • Matthew D. Slein
  • Callaghan R. Garland
  • David M. Knipe

Key recent publications authored by or including David A. Leib are:

  • Limited astrocyte-to-neuron conversion in the mouse brain using NeuroD1 overexpression, 2022, Molecular Therapy
  • Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies, 2020, PLoS Pathogens
  • Trivalent Glycoprotein Subunit Vaccine Prevents Neonatal Herpes Simplex Virus Mortality and Morbidity, 2020, Journal of Virology
  • Herpes Simplex Virus 1 ICP34.5 Alters Mitochondrial Dynamics in Neurons, 2020, Journal of Virology
  • Models of Herpes Simplex Virus Latency, 2024, Viruses

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein.

    Anthony Orvedahl;Diane Alexander;Zsolt Tallóczy;Qihua Sun

  • Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

    Anne Krug;Gary D. Luker;Gary D. Luker;Winfried Barchet;Winfried Barchet;David A. Leib;David A. Leib

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway

    Zsolt Tallóczy;Wenxia Jiang;Herbert W. Virgin;David A. Leib

  • IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses.

    Deborah J. Lenschow;Caroline Lai;Natalia Frias-Staheli;Nadia V. Giannakopoulos

  • Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection.

    Luc English;Magali Chemali;Johanne Duron;Christiane Rondeau

  • Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate

    Donald M. Coen;Magdalena Kosz-Vnenchak;Jennie G. Jacobson;David A. Leib

  • Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.

    D A Leib;D M Coen;C L Bogard;K A Hicks

  • A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency

    D A Leib;C L Bogard;M Kosz-Vnenchak;K A Hicks

  • Interferons Regulate the Phenotype of Wild-type and Mutant Herpes Simplex Viruses In Vivo

    David A. Leib;Travis E. Harrison;Kathleen M. Laslo;Michael A. Machalek

  • Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene.

    David A. Leib;Michael A. Machalek;Bryan R. G. Williams;Robert H. Silverman

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells.

    Jennie G. Jacobson;David A. Leib;David J. Goldstein;Connie L. Bogard

  • Noninvasive Bioluminescence Imaging of Herpes Simplex Virus Type 1 Infection and Therapy in Living Mice

    Gary D. Luker;J. Patrick Bardill;Julie L. Prior;Christina M. Pica

  • The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency.

    David A. Leib;Kari C. Nadeau;Scott A. Rundle;Priscilla A. Schaffer

  • Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

    Jie Deng;Jiannan Li;Aurelien Sarde;J Louise Lines

  • Role of the Virion Host Shutoff (vhs) of Herpes Simplex Virus Type 1 in Latency and Pathogenesis

    L I Strelow;D A Leib

  • Analysis of the Role of Autophagy in Replication of Herpes Simplex Virus in Cell Culture

    Diane E. Alexander;Stephen L. Ward;Stephen L. Ward;Noboru Mizushima;Beth Levine

  • Interaction of ICP34.5 with Beclin 1 Modulates Herpes Simplex Virus Type 1 Pathogenesis through Control of CD4+ T-Cell Responses

    David A. Leib;Diane E. Alexander;Douglas Cox;Jiyi Yin

Frequent Co-Authors

Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Gary D. Luker
Gary D. Luker University of Michigan–Ann Arbor
Donald M. Coen
Donald M. Coen Harvard University
Priscilla A. Schaffer
Priscilla A. Schaffer Beth Israel Deaconess Medical Center
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Felix Randow
Felix Randow MRC Laboratory of Molecular Biology
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco

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