Koichi Nakajima

Overview

Best Publications

• Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

  Toshio Hirano;Kiyoshi Yasukawa;Hisashi Harada;Tetsuya Taga

  2802
  Citations

• The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.

  Atsushi Muraguchi;Toshio Hirano;Bo Tang;Tadashi Matsuda

  1080
  Citations

• Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

  Toshio Hirano;Tetsuya Taga;Naoko Nakano;Kiyosi Yasukawa

  951
  Citations

• Two Signals Are Necessary for Cell Proliferation Induced by a Cytokine Receptor gp130: Involvement of STAT3 in Anti-Apoptosis

  Toshiyuki Fukada;Masahiko Hibi;Yojiro Yamanaka;Mariko Takahashi-Tezuka

  856
  Citations

• Infection with HIV is associated with elevated IL-6 levels and production.

  E C Breen;A R Rezai;K Nakajima;G N Beall

  722
  Citations

• A central role for Stat3 in IL‐6‐induced regulation of growth and differentiation in M1 leukemia cells.

  K. Nakajima;Y. Yamanaka;K. Nakae;H. Kojima

  676
  Citations

• Extracellular signal‐dependent nuclear import of Stat1 is mediated by nuclear pore‐targeting complex formation with NPI‐1, but not Rch1

  Toshihiro Sekimoto;Naoko Imamoto;Koichi Nakajima;Toshio Hirano

  513
  Citations

• STAT3 Is Required for the gp130-mediated Full Activation of the c-myc Gene

  Nobuo Kiuchi;Koichi Nakajima;Makoto Ichiba;Toshiyuki Fukada

  505
  Citations

• Signaling mechanisms through gp130: a model of the cytokine system

  Toshio Hirano;Koichi Nakajima;Masahiko Hibi

  484
  Citations

• Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production

  T. Hirano;T. Taga;K. Yasukawa;K. Nakajima

  462
  Citations

• Gab1 Acts as an Adapter Molecule Linking the Cytokine Receptor gp130 to ERK Mitogen-Activated Protein Kinase

  Mariko Takahashi-Tezuka;Yuichi Yoshida;Toshiyuki Fukada;Takuya Ohtani

  370
  Citations

• Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV.

  K Nakajima;O Martínez-Maza;T Hirano;E C Breen

  363
  Citations

• IL-6 cytokine family and signal transduction: a model of the cytokine system

  M. Hibi;K. Nakajima;T. Hirano

  337
  Citations

• STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition

  Toshiyuki Fukada;Takuya Ohtani;Yuichi Yoshida;Takahiro Shirogane

  330
  Citations

• Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation.

  Y. Yamanaka;K. Nakajima;T. Fukada;M. Hibi

  274
  Citations

• INVOLVEMENT OF STAT3 IN THE GRANULOCYTE COLONY-STIMULATING FACTOR-INDUCED DIFFERENTIATION OF MYELOID CELLS

  Koji Shimozaki;Koji Shimozaki;Koichi Nakajima;Toshio Hirano;Shigekazu Nagata;Shigekazu Nagata

  249
  Citations

• Signal transduction through gp130 that is shared among the receptors for the interleukin 6 related cytokine subfamily

  Toshio Hirano;Tadashi Matsuda;Koichi Nakajima

  243
  Citations

• Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5.

  Itaru Matsumura;Jun Ishikawa;Koichi Nakajima;Kenji Oritani

  236
  Citations

• An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.

  Yoshio Fujitani;Masahiko Hibi;Toshiyuki Fukada;Mariko Takahashi-Tezuka

  219
  Citations

• Roles for c-Myc in self-renewal of hematopoietic stem cells

  Yusuke Satoh;Itaru Matsumura;Hirokazu Tanaka;Sachiko Ezoe

  197
  Citations