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Microbiology

D-Index
57
Citations
10012
World Ranking
3615
National Ranking
320

Overview

Kenneth D. Bruce is affiliated with King's College London in the United Kingdom. Their research primarily focuses on the intersections of medicine and biochemistry, genetics, and molecular biology. The scientist's work spans several subfields including molecular biology, pulmonary and respiratory medicine, physiology, epidemiology, and infectious diseases.

The main topics addressed in Kenneth D. Bruce's research include:

  • Gut microbiota and health
  • Cystic fibrosis research advances
  • Clostridium difficile and Clostridium perfringens research
  • Antibiotic resistance in bacteria
  • Bacterial biofilms and quorum sensing
  • Liver disease diagnosis and treatment
  • Asthma and respiratory diseases

The scientist has contributed to a significant number of publications, particularly in the following venues:

  • Journal of Medical Microbiology (2 publications)
  • Journal of Cystic Fibrosis (2 publications)
  • Microbiome
  • Journal of Hepatology
  • Journal of Allergy and Clinical Immunology

Recent notable papers authored or co-authored by Kenneth D. Bruce include:

  • "Lung function and microbiota diversity in cystic fibrosis," 2020, Microbiome
  • "Rifaximin-α reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial," 2021, Journal of Hepatology
  • "Gut microbiota development during infancy: Impact of introducing allergenic foods," 2021, Journal of Allergy and Clinical Immunology
  • "Peripheral airways type 2 inflammation, neutrophilia and microbial dysbiosis in severe asthma," 2021, Allergy
  • "Design and manufacture of a lyophilised faecal microbiota capsule formulation to GMP standards," 2022, Journal of Controlled Release

Kenneth D. Bruce has frequently collaborated with several researchers, with multiple joint publications. The most frequent co-authors are:

  • Nur Masirah M. Zain (8 publications)
  • Garrit Koller (5 publications)
  • Andrew Lilley (4 publications)
  • Andrew Fogarty (4 publications)
  • E.F. Nash (4 publications)

The research contributions by Kenneth D. Bruce often focus on investigating microbial communities in relation to respiratory diseases such as cystic fibrosis and asthma, as well as exploring gut microbiota implications in health and disease. Studies also cover antibiotic resistance dynamics and the biochemistry involved in bacterial biofilms and quorum sensing mechanisms.

Best Publications

  • Structure and function of the soil microbial community in microhabitats of a heavy metal polluted soil.

    Ellen Kandeler;D. Tscherko;K. D. Bruce;M. Stemmer

  • Distribution, diversity and evolution of the bacterial mercury resistance (mer) operon

    A.Mark Osborn;Kenneth D Bruce;Peter Strike;Donald A Ritchie

  • characterization of bacterial community diversity in cystic fibrosis lung infections by use of 16s ribosomal DNA terminal restriction fragment length polymorphism profiling

    G. B. Rogers;M. P. Carroll;D. J. Serisier;P. M. Hockey

  • Potentially Pathogenic Airway Bacteria and Neutrophilic Inflammation in Treatment Resistant Severe Asthma

    Benjamin J. Green;Surasa Wiriyachaiporn;Christopher Grainge;Geraint B. Rogers

  • Impacts of Rising Atmospheric Carbon Dioxide on Model Terrestrial Ecosystems

    T. H. Jones;L. J. Thompson;J. H. Lawton;T. M. Bezemer

  • Amplification of DNA from native populations of soil bacteria by using the polymerase chain reaction.

    K D Bruce;W D Hiorns;J L Hobman;A M Osborn

  • Bacterial Diversity in Cases of Lung Infection in Cystic Fibrosis Patients: 16S Ribosomal DNA (rDNA) Length Heterogeneity PCR and 16S rDNA Terminal Restriction Fragment Length Polymorphism Profiling

    G B Rogers;C A Hart;Jeremy Mason;M Hughes

  • Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities

    Christopher J van der Gast;Alan W Walker;Franziska A Stressmann;Geraint B Rogers

  • The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: an analysis from the randomised, double-blind, placebo-controlled BLESS trial

    Geraint B Rogers;Kenneth D Bruce;Megan L Martin;Lucy D Burr

  • Lung function and microbiota diversity in cystic fibrosis

    Leah Cuthbertson;Alan W. Walker;Alan W. Walker;Anna E. Oliver;Geraint B. Rogers

  • A Novel Microbiota Stratification System Predicts Future Exacerbations in Bronchiectasis

    Geraint B. Rogers;Nur Masirah M. Zain;Kenneth D. Bruce;Lucy D. Burr

  • Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition

    Geraint B Rogers;Christopher J van der Gast;Leah Cuthbertson;Serena K Thomson

  • Staphylococcus aureus Small-Colony Variants Are Independently Associated With Worse Lung Disease in Children With Cystic Fibrosis

    Daniel J. Wolter;Julia C. Emerson;Sharon McNamara;Anne M. Buccat

  • Use of 16S rRNA Gene Profiling by Terminal Restriction Fragment Length Polymorphism Analysis To Compare Bacterial Communities in Sputum and Mouthwash Samples from Patients with Cystic Fibrosis

    G. B. Rogers;G. B. Rogers;M. P. Carroll;D. J. Serisier;P. M. Hockey

  • Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis.

    Robert P Howlin;Katrina Cathie;Katrina Cathie;Luanne Hall-Stoodley;Luanne Hall-Stoodley;Victoria Cornelius

  • Rifaximin reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial

    Vishal C. Patel;Vishal C. Patel;Vishal C. Patel;Sunjae Lee;Sunjae Lee;Mark McPhail;Mark McPhail;Kevin Da Silva

  • Does bacterial density in cystic fibrosis sputum increase prior to pulmonary exacerbation

    Franziska A. Stressmann;Geraint B. Rogers;Peter Marsh;Andrew K. Lilley

  • Long-term cultivation-independent microbial diversity analysis demonstrates that bacterial communities infecting the adult cystic fibrosis lung show stability and resilience.

    Franziska Anne Stressmann;Geraint B Rogers;Christopher J van der Gast;Peter Marsh

  • Environmentally determined differences in the murine lung microbiota and their relation to alveolar architecture

    Yeojun Yun;Girish Srinivas;Sven Kuenzel;Miriam Linnenbrink

  • TRPV1 Deletion Enhances Local Inflammation and Accelerates the Onset of Systemic Inflammatory Response Syndrome

    Elizabeth S. Fernandes;Lihuan Liang;Sarah-Jane Smillie;Frank Kaiser

  • Analysis of mer Gene Subclasses within Bacterial Communities in Soils and Sediments Resolved by Fluorescent-PCR-Restriction Fragment Length Polymorphism Profiling.

    Kenneth D. Bruce

Frequent Co-Authors

Geraint B. Rogers
Geraint B. Rogers Flinders University
Lucas R. Hoffman
Lucas R. Hoffman University of Washington
Alan W. Walker
Alan W. Walker University of Aberdeen
Julian Parkhill
Julian Parkhill University of Cambridge
Peter H. Howarth
Peter H. Howarth University of Southampton
Jeremy D. Sanderson
Jeremy D. Sanderson Guy's and St Thomas' NHS Foundation Trust
Gideon Lack
Gideon Lack King's College London
Carsten Flohr
Carsten Flohr King's College London
Julia Wendon
Julia Wendon King's College London
Richard D. Bardgett
Richard D. Bardgett Lancaster University

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