2009 - Fellow of the American Association for the Advancement of Science (AAAS)
Genetics, Gene, Genome, Virology and Immunology are his primary areas of study. His work in Nonsynonymous substitution, Gene duplication, Phylogenetics, Gene family and Genome evolution is related to Genetics. In his study, Smallpox and Comparative genomics is strongly linked to Host, which falls under the umbrella field of Gene.
Austin L. Hughes has researched Genome in several fields, including Nucleotide diversity, DNA sequencing and Plasmodium falciparum. His work investigates the relationship between Virology and topics such as Epitope that intersect with problems in Major histocompatibility complex. His study on CTL*, Immune system, Viremia and Cellular immunity is often connected to HIV vaccine as part of broader study in Immunology.
Austin L. Hughes spends much of his time researching Genetics, Gene, Genome, Phylogenetic tree and Nonsynonymous substitution. He frequently studies issues relating to Virology and Genetics. His Virology research is multidisciplinary, relying on both Major histocompatibility complex, CTL* and Immunology.
His Genome study frequently involves adjacent topics like Evolutionary biology. His Phylogenetic tree research is multidisciplinary, incorporating elements of Peptide sequence and Vertebrate. His study explores the link between Nonsynonymous substitution and topics such as Nucleotide diversity that cross with problems in Genetic diversity.
His main research concerns Genetics, Phylogenetic tree, Virology, Phylogenetics and Ecology. Genome, Nucleotide diversity, Nonsynonymous substitution, Negative selection and Gene are subfields of Genetics in which his conducts study. His studies deal with areas such as Evolutionary biology, Human evolutionary genetics and Metagenomics as well as Negative selection.
His work deals with themes such as Amino acid, Peptide sequence and Gene duplication, which intersect with Phylogenetic tree. Austin L. Hughes interconnects Viral evolution and Immunology in the investigation of issues within Virology. His Phylogenetics study incorporates themes from Chaos game representation, Viral genomes, Family Flaviviridae, Cluster analysis and Old World monkey.
His primary areas of study are Genetics, Virology, Virus, Nucleotide diversity and Phylogenetics. His Genetics study frequently draws connections to adjacent fields such as Hepatitis C. His Virology research incorporates elements of Viral evolution, CD8, Immunology and Pyrosequencing.
The Simian immunodeficiency virus, T cell, Epitope and Viral load research Austin L. Hughes does as part of his general Immunology study is frequently linked to other disciplines of science, such as Simian immunodeficiency virus infection, therefore creating a link between diverse domains of science. Austin L. Hughes combines subjects such as Evolutionary biology, Effective population size, Natural selection, Nonsynonymous substitution and DNA sequencing with his study of Nucleotide diversity. His Natural selection research integrates issues from Genetic variation, Genome, Reference genome, Host and Computational biology.
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Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.
Todd M. Allen;David H. O'Connor;Peicheng Jing;John L. Dzuris.
Nature (2000)
The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes.
Ann L Erickson;Yoichi Kimura;Suzu Igarashi;Jennifer Eichelberger.
Immunity (2001)
Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Thomas C Friedrich;Elizabeth J Dodds;Levi J Yant;Lara Vojnov.
Nature Medicine (2004)
Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection.
David H. O'Connor;Todd M. Allen;Thorsten U. Vogel;Peicheng Jing.
Nature Medicine (2002)
A genome-wide screen identifies a single β-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins
Yanjing Xiao;Austin L. Hughes;Junko Ando;Yoichi Matsuda.
BMC Genomics (2004)
Evolution of duplicate genes in a tetraploid animal, Xenopus laevis.
Marianne K. Hughes;Austin L. Hughes.
Molecular Biology and Evolution (1993)
Looking for Darwin in all the wrong places: the misguided quest for positive selection at the nucleotide sequence level
A L Hughes.
Heredity (2007)
Pattern and timing of gene duplication in animal genomes.
Robert Friedman;Austin L. Hughes.
Genome Research (2001)
Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.
David H. O'Connor;Bianca R. Mothe;Jason T. Weinfurter;Sarah Fuenger.
Journal of Virology (2003)
Gene Duplication and the Structure of Eukaryotic Genomes
Robert Friedman;Austin L. Hughes.
Genome Research (2001)
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