D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 66 Citations 12,913 229 World Ranking 1846 National Ranking 842

Research.com Recognitions

Awards & Achievements

2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • DNA

Genetics, Gene, Genome, Virology and Immunology are his primary areas of study. His work in Nonsynonymous substitution, Gene duplication, Phylogenetics, Gene family and Genome evolution is related to Genetics. In his study, Smallpox and Comparative genomics is strongly linked to Host, which falls under the umbrella field of Gene.

Austin L. Hughes has researched Genome in several fields, including Nucleotide diversity, DNA sequencing and Plasmodium falciparum. His work investigates the relationship between Virology and topics such as Epitope that intersect with problems in Major histocompatibility complex. His study on CTL*, Immune system, Viremia and Cellular immunity is often connected to HIV vaccine as part of broader study in Immunology.

His most cited work include:

  • Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. (673 citations)
  • The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes. (379 citations)
  • Reversion of CTL escape-variant immunodeficiency viruses in vivo. (368 citations)

What are the main themes of his work throughout his whole career to date?

Austin L. Hughes spends much of his time researching Genetics, Gene, Genome, Phylogenetic tree and Nonsynonymous substitution. He frequently studies issues relating to Virology and Genetics. His Virology research is multidisciplinary, relying on both Major histocompatibility complex, CTL* and Immunology.

His Genome study frequently involves adjacent topics like Evolutionary biology. His Phylogenetic tree research is multidisciplinary, incorporating elements of Peptide sequence and Vertebrate. His study explores the link between Nonsynonymous substitution and topics such as Nucleotide diversity that cross with problems in Genetic diversity.

He most often published in these fields:

  • Genetics (68.98%)
  • Gene (34.69%)
  • Genome (24.49%)

What were the highlights of his more recent work (between 2011-2018)?

  • Genetics (68.98%)
  • Phylogenetic tree (22.45%)
  • Virology (18.78%)

In recent papers he was focusing on the following fields of study:

His main research concerns Genetics, Phylogenetic tree, Virology, Phylogenetics and Ecology. Genome, Nucleotide diversity, Nonsynonymous substitution, Negative selection and Gene are subfields of Genetics in which his conducts study. His studies deal with areas such as Evolutionary biology, Human evolutionary genetics and Metagenomics as well as Negative selection.

His work deals with themes such as Amino acid, Peptide sequence and Gene duplication, which intersect with Phylogenetic tree. Austin L. Hughes interconnects Viral evolution and Immunology in the investigation of issues within Virology. His Phylogenetics study incorporates themes from Chaos game representation, Viral genomes, Family Flaviviridae, Cluster analysis and Old World monkey.

Between 2011 and 2018, his most popular works were:

  • Evolution of Divergent Life History Strategies in Marine Alphaproteobacteria (77 citations)
  • SNPGenie: estimating evolutionary parameters to detect natural selection using pooled next-generation sequencing data (74 citations)
  • A Novel Hepacivirus with an Unusually Long and Intrinsically Disordered NS5A Protein in a Wild Old World Primate (70 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genome

His primary areas of study are Genetics, Virology, Virus, Nucleotide diversity and Phylogenetics. His Genetics study frequently draws connections to adjacent fields such as Hepatitis C. His Virology research incorporates elements of Viral evolution, CD8, Immunology and Pyrosequencing.

The Simian immunodeficiency virus, T cell, Epitope and Viral load research Austin L. Hughes does as part of his general Immunology study is frequently linked to other disciplines of science, such as Simian immunodeficiency virus infection, therefore creating a link between diverse domains of science. Austin L. Hughes combines subjects such as Evolutionary biology, Effective population size, Natural selection, Nonsynonymous substitution and DNA sequencing with his study of Nucleotide diversity. His Natural selection research integrates issues from Genetic variation, Genome, Reference genome, Host and Computational biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.

Todd M. Allen;David H. O'Connor;Peicheng Jing;John L. Dzuris.
Nature (2000)

917 Citations

The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes.

Ann L Erickson;Yoichi Kimura;Suzu Igarashi;Jennifer Eichelberger.
Immunity (2001)

516 Citations

Reversion of CTL escape-variant immunodeficiency viruses in vivo.

Thomas C Friedrich;Elizabeth J Dodds;Levi J Yant;Lara Vojnov.
Nature Medicine (2004)

473 Citations

Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection.

David H. O'Connor;Todd M. Allen;Thorsten U. Vogel;Peicheng Jing.
Nature Medicine (2002)

454 Citations

A genome-wide screen identifies a single β-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins

Yanjing Xiao;Austin L. Hughes;Junko Ando;Yoichi Matsuda.
BMC Genomics (2004)

377 Citations

Evolution of duplicate genes in a tetraploid animal, Xenopus laevis.

Marianne K. Hughes;Austin L. Hughes.
Molecular Biology and Evolution (1993)

331 Citations

Looking for Darwin in all the wrong places: the misguided quest for positive selection at the nucleotide sequence level

A L Hughes.
Heredity (2007)

317 Citations

Pattern and timing of gene duplication in animal genomes.

Robert Friedman;Austin L. Hughes.
Genome Research (2001)

275 Citations

Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.

David H. O'Connor;Bianca R. Mothe;Jason T. Weinfurter;Sarah Fuenger.
Journal of Virology (2003)

247 Citations

Gene Duplication and the Structure of Eukaryotic Genomes

Robert Friedman;Austin L. Hughes.
Genome Research (2001)

241 Citations

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