Michael Foley

Overview

Best Publications

• Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

  Lakshmi Raj;Takao Ide;Aditi U. Gurkar;Michael Foley

  1189
  Citations

• Quinoline Antimalarials: Mechanisms of Action and Resistance and Prospects for New Agents

  Michael Foley;Leann Tilley

  794
  Citations

• Systematic discovery of multicomponent therapeutics

  Alexis A. Borisy;Peter J. Elliott;Nicole W. Hurst;Margaret S. Lee

  750
  Citations

• Inhibition of the peroxidative degradation of haem as the basis of action of chloroquine and other quinoline antimalarials.

  Paul Loria;Susanne Miller;Michael Foley;Leann Tilley

  403
  Citations

• High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines

  Channing Yu;Aristotle M. Mannan;Griselda Metta Yvone;Kenneth N. Ross

  329
  Citations

• Discovery of novel targets of quinoline drugs in the human purine binding proteome.

  Paul R. Graves;Jesse J. Kwiek;Patrick Fadden;Rupa Ray

  321
  Citations

• Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites

  Dave Richard;Christopher A. MacRaild;David T. Riglar;Jo-Anne Chan

  305
  Citations

• Stereoselective Synthesis of over Two Million Compounds Having Structural Features Both Reminiscent of Natural Products and Compatible with Miniaturized Cell-Based Assays

  Derek S. Tan;Michael A. Foley;Matthew D. Shair;Stuart L. Schreiber

  287
  Citations

• Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

  Nobutaka Kato;Eamon Comer;Tomoyo Sakata-Kato;Arvind Sharma

  241
  Citations

• An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors

  Lisa A. Marcaurelle;Eamon Comer;Sivaraman Dandapani;Jeremy R. Duvall

  231
  Citations

• Structural and conformational determinants of macrocycle cell permeability

  Björn Over;Pär Matsson;Pär Matsson;Christian Tyrchan;Per Artursson;Per Artursson

  203
  Citations

• Synthesis and Preliminary Evaluation of a Library of Polycyclic Small Molecules for Use in Chemical Genetic Assays

  Derek S. Tan;Michael A. Foley;Brent R. Stockwell;Matthew D. Shair

  173
  Citations

• Advancing Biological Understanding and Therapeutics Discovery with Small Molecule Probes

  Stuart L. Schreiber;Stuart L. Schreiber;Joanne D. Kotz;Min Li;Min Li;Jeffrey Aubé

  172
  Citations

• Inhibition of heme detoxification processes underlies the antimalarial activity of terpene isonitrile compounds from marine sponges.

  Anthony D. Wright;Huiqin Wang;Marion Gurrath;Gabriele M. König

  172
  Citations

• The ring-infected erythrocyte surface antigen of Plasmodium falciparum associates with spectrin in the erythrocyte membrane.

  Michael Foley;Leann Tilley;William H. Sawyer;Robin F. Anders

  172
  Citations

• A second merozoite surface protein (MSP-4) of Plasmodium falciparum that contains an epidermal growth factor-like domain.

  Vikki M Marshall;Anabel Silva;Michael Foley;Sue Cranmer

  159
  Citations

• Semisynthetic Cyclopamine Analogues as Potent and Orally Bioavailable Hedgehog Pathway Antagonists

  Martin R. Tremblay;Marta Nevalainen;Somarajan J. Nair;James R. Porter

  159
  Citations

• A one-bead, one-stock solution approach to chemical genetics: part 1

  Helen E Blackwell;Helen E Blackwell;Lucy Pérez;Lucy Pérez;Robert A Stavenger;Robert A Stavenger;John A Tallarico

  156
  Citations

• A highly stereocontrolled, four-step synthesis of (.+-.)-lasubine II

  Jack D. Brown;Michael A. Foley;Daniel L. Comins

  149
  Citations

• The Most Polymorphic Residue on Plasmodium falciparum Apical Membrane Antigen 1 Determines Binding of an Invasion-Inhibitory Antibody

  A. M. Coley;K. Parisi;R. Masciantonio;J. Hoeck

  147
  Citations