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Chemistry

D-Index
62
Citations
14852
World Ranking
8761
National Ranking
2508

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

George I. Makhatadze is affiliated with Rensselaer Polytechnic Institute in the United States. Their research primarily aligns with the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Physiology, Atomic and Molecular Physics, and Optics, as well as Biomaterials and Materials Chemistry.

The scientist's work extensively covers topics including Protein Structure and Dynamics, Alzheimer's disease research and treatments, Enzyme Structure and Function, Spectroscopy and Quantum Chemical Studies, DNA and Nucleic Acid Chemistry, Crystallography and molecular interactions, and Supramolecular Self-Assembly in Materials.

Frequent coauthors collaborating with George I. Makhatadze include Caitlyn Moustouka, Richard E. Gillilan, Catherine A. Royer, Anthony C. Bishop, and Scott A. McCallum.

George I. Makhatadze has contributed to multiple scientific publications, with recent papers including:

  • The Molecular Basis for Life in Extreme Environments (2021), published in Annual Review of Biophysics
  • Sequence-independent recognition of the amyloid structural motif by GFP protein family (2020), published in Proceedings of the National Academy of Sciences
  • From Protein Design to the Energy Landscape of a Cold Unfolding Protein (2022), published in The Journal of Physical Chemistry B
  • A solution structure analysis reveals a bent collagen triple helix in the complement activation recognition molecule mannan-binding lectin (2022), published in Journal of Biological Chemistry
  • The volume changes of unfolding of dsDNA (2022), published in Biophysical Journal

Their research work is frequently published in venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, The Journal of Physical Chemistry B, bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, and Biophysical Journal.

In 2019, George I. Makhatadze was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Energetics of protein structure.

    George I. Makhatadze;Peter L. Privalov

  • Protein interactions with urea and guanidinium chloride. A calorimetric study.

    George I. Makhatadze;George I. Makhatadze;Peter L. Privalov;Peter L. Privalov

  • Heat capacity of proteins. I. Partial molar heat capacity of individual amino acid residues in aqueous solution: hydration effect.

    G.I. Makhatadze;P.L. Privalov

  • Contribution of Hydration to Protein Folding Thermodynamics: I. The Enthalpy of Hydration

    George I. Makhatadze;Peter L. Privalov

  • Contribution of Hydration to Protein Folding Thermodynamics: II. The Entropy and Gibbs Energy of Hydration

    Peter L. Privalov;George I. Makhatadze

  • Heat capacity of proteins. II. Partial molar heat capacity of the unfolded polypeptide chain of proteins: protein unfolding effects.

    P L Privalov;G I Makhatadze

  • Protein stability and surface electrostatics: a charged relationship.

    Samantha S Strickler;Alexey V Gribenko;Alexander V Gribenko;Timothy R Keiffer

  • Heat capacity and conformation of proteins in the denatured state

    P.L. Privalov;E.I. Tiktopulo;S.Yu. Venyaminov;Yu.V. Griko

  • Contribution of hydration and non-covalent interactions to the heat capacity effect on protein unfolding

    Peter L. Privalov;George I. Makhatadze;George I. Makhatadze

  • Thermal versus Guanidine-Induced Unfolding of Ubiquitin. An Analysis in Terms of the Contributions from Charge−Charge Interactions to Protein Stability†

    Beatriz Ibarra-Molero;Vakhtang V. Loladze;George I. Makhatadze;Jose M. Sanchez-Ruiz

  • Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface.

    Vakhtang V. Loladze;Beatriz Ibarra-Molero;Jose M. Sanchez-Ruiz;George I. Makhatadze

  • Contribution of surface salt bridges to protein stability: guidelines for protein engineering.

    George I. Makhatadze;Vakhtang V. Loladze;Dmitri N. Ermolenko;Dmitri N. Ermolenko;XiaoFen Chen

  • To charge or not to charge

    Jose M. Sanchez-Ruiz;George I. Makhatadze

  • Rational stabilization of enzymes by computational redesign of surface charge-charge interactions.

    Alexey V. Gribenko;Mayank M. Patel;Jiajing Liu;Scott A. McCallum

  • Solvent isotope effect and protein stability

    George I. Makhatadze;G. Marius Clore;Angela M. Gronenborn

  • Thermodynamics of ubiquitin unfolding

    Patrick L. Wintrode;George I. Makhatadze;Peter L. Privalov

  • Thermodynamics of Protein Interactions with Urea and Guanidinium Hydrochloride

    George I. Makhatadze

  • Molecular mechanism for the preferential exclusion of TMAO from protein surfaces.

    Deepak R Canchi;Pruthvi Jayasimha;Donald C Rau;George I Makhatadze

  • Partial molar volumes of polypeptides and their constituent groups in aqueous solution over a broad temperature range.

    G. I. Makhatadze;V. N. Medvedkin;P. L. Privalov

  • Differential scanning calorimetry.

    Maria M. Lopez;George I. Makhatadze

  • Isothermal titration calorimetry.

    Maria M. Lopez;George I. Makhatadze

Frequent Co-Authors

Angel E. Garcia
Angel E. Garcia Los Alamos National Laboratory
Jose M. Sanchez-Ruiz
Jose M. Sanchez-Ruiz University of Granada
Anthony A. Kossiakoff
Anthony A. Kossiakoff University of Chicago
Stephen B. H. Kent
Stephen B. H. Kent University of Chicago
Angela M. Gronenborn
Angela M. Gronenborn University of Pittsburgh
Katsuhide Yutani
Katsuhide Yutani Osaka University
Barbara Brodsky
Barbara Brodsky Tufts University
Yuriko Yamagata
Yuriko Yamagata Kumamoto University
Catherine A. Royer
Catherine A. Royer Rensselaer Polytechnic Institute
Alan R. Davidson
Alan R. Davidson University of Toronto

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