World's Best Scientists 2026 revealed!
Peter H. von Hippel

Peter H. von Hippel

D-Index & Metrics

Molecular Biology

D-Index
68
Citations
22857
World Ranking
1498
National Ranking
760

Research.com Recognitions

  • 1979 - Fellow of the American Academy of Arts and Sciences
  • 1978 - Member of the National Academy of Sciences
  • 1973 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Peter H. von Hippel is affiliated with the University of Oregon in the United States. Their research contributions span multiple areas within biochemistry, genetics, and molecular biology, with a particular focus on molecular biology as reflected by the high number of related publications.

Their recent papers cover diverse topics primarily in DNA and nucleic acid chemistry as well as advanced biosensing techniques and spectroscopy. Noteworthy recent publications include:

  • Temperature-dependent local conformations and conformational distributions of cyanine dimer labeled single-stranded-double-stranded DNA junctions by 2D fluorescence spectroscopy (2021, The Journal of Chemical Physics)
  • Submillisecond Conformational Transitions of Short Single-Stranded DNA Lattices by Photon Correlation Single-Molecule Förster Resonance Energy Transfer (2021, The Journal of Physical Chemistry B)
  • Mapping DNA conformations and interactions within the binding cleft of bacteriophage T4 single-stranded DNA binding protein (gp32) at single nucleotide resolution (2020, Nucleic Acids Research)
  • Studies of DNA 'Breathing' by Polarization-Sweep Single-Molecule Fluorescence Microscopy of Exciton-Coupled (iCy3)2 Dimer-Labeled DNA Fork Constructs (2023, The Journal of Physical Chemistry B)
  • Studies of Local DNA Backbone Conformation and Conformational Disorder Using Site-Specific Exciton-Coupled Dimer Probe Spectroscopy (2023, Annual Review of Physical Chemistry)

Von Hippel frequently collaborates with a core group of coauthors, including:

  • Andrew H. Marcus
  • Dylan Heussman
  • Jack Maurer
  • Claire S. Albrecht
  • Patrick J. Herbert

Their research appears consistently in leading scientific journals, with prolific publications in:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • The Journal of Physical Chemistry B
  • The Journal of Chemical Physics

The primary fields of study include biochemistry, genetics, and molecular biology, with subfields covering molecular biology, atomic and molecular physics and optics, physical and theoretical chemistry, genetics, and ecology.

Main topics explored in von Hippel's work encompass:

  • DNA and nucleic acid chemistry
  • Advanced biosensing and bioanalysis techniques
  • Spectroscopy and quantum chemical studies
  • DNA repair mechanisms
  • Photochemistry and electron transfer studies
  • Bacterial genetics and biotechnology
  • Protein interaction studies and fluorescence analysis

Peter H. von Hippel has received several notable recognitions, including being named a Member of the National Academy of Sciences in 1978, a Fellow of the American Academy of Arts and Sciences in 1979, and a Fellow of the John Simon Guggenheim Memorial Foundation in 1973.

Best Publications

  • Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice.

    James D. McGhee;Peter H. von Hippel

  • Diffusion-Driven Mechanisms of Protein Translocation on Nucleic Acids. 1. Models and Theory?

    Otto G. Berg;Robert B. Winter;Peter H. Von Hippel

  • Selection of DNA Binding Sites by Regulatory Proteins Statistical-mechanical Theory and Application to Operators and Promoters

    Otto G. Berg;Peter H. von Hippel

  • Diffusion-driven mechanisms of protein translocation on nucleic acids. 3. The Escherichia coli lac repressor-operator interaction: kinetic measurements and conclusions

    Robert B. Winter;Otto G. Berg;Peter H. Von Hippel

  • DNA-Protein Interactions

    Peter H. von Hippel;James D. McGhee

  • Diffusion-driven mechanisms of protein translocation on nucleic acids. 2. The Escherichia coli repressor--operator interaction: equilibrium measurements.

    Robert B. Winter;Peter H. Von Hippel

  • Interactions of bacteriophage T4-coded gene 32 protein with nucleic acids. I. Characterization of the binding interactions.

    Stephen C. Kowalczykowski;Nils Lonberg;John W. Newport;Peter H. von Hippel

  • Action at a distance: DNA-looping and initiation of transcription

    Karsten Rippe;Peter H. von Hippel;Jörg Langowski

  • An Integrated Model of the Transcription Complex in Elongation, Termination, and Editing

    Peter H. von Hippel

  • Non-specific DNA Binding of Genome Regulating Proteins as a Biological Control Mechanism: 1. The lac Operon: Equilibrium Aspects

    Peter H. Von Hippel;Arnold Revzin;Carol A. Gross;Amy C. Wang

  • Formaldehyde as a probe of DNA structure. I. Reaction with exocyclic amino groups of DNA bases.

    McGhee Jd;von Hippel Ph

  • Cooperative and noncooperative binding of protein ligands to nucleic acid lattices: experimental approaches to the determination of thermodynamic parameters.

    S C Kowalczykowski;L S Paul;N Lonberg;J W Newport

  • Kinetics of protein-nucleic acid interactions: use of salt effects to probe mechanisms of interaction.

    Timothy M. Lohman;Peter H. von Hippel

  • From "Simple" DNA-Protein Interactions to the Macromolecular Machines of Gene Expression

    Peter H. von Hippel

  • Helicase mechanisms and the coupling of helicases within macromolecular machines. Part II: Integration of helicases into cellular processes.

    Emmanuelle Delagoutte;Peter H. von Hippel

  • Effects of methylation on the stability of nucleic acid conformations: studies at the monomer level.

    James D. Engel;Peter H. Von Hippel

  • Helicase mechanisms and the coupling of helicases within macromolecular machines Part I: Structures and properties of isolated helicases

    Emmanuelle Delagoutte;Peter H. von Hippel

  • Interactions of bacteriophage T4-coded gene 32 protein with nucleic acids: II. Specificity of binding to DNA and RNA

    John W. Newport;Nils Lonberg;Stephen C. Kowalczykowski;Peter H. von Hippel

  • Direct measurement of association constants for the binding of Escherichia coli lac repressor to non-operator DNA

    Arnold Revzin;Peter H. Von Hippel

  • Nonspecific DNA binding of genome-regulating proteins as a biological control mechanism: Measurement of DNA-bound Escherichia coli lac repressor in vivo

    Ying Kao-Huang;Arnold Revzin;Andrew P. Butler;Pamela O'Conner

Frequent Co-Authors

Stephen C. Kowalczykowski
Stephen C. Kowalczykowski University of California, Davis
Otto G. Berg
Otto G. Berg Uppsala University
James D. McGhee
James D. McGhee Alberta Children's Hospital
Carol A. Gross
Carol A. Gross University of California, San Francisco
Howard K. Schachman
Howard K. Schachman University of California, Berkeley
Michelle A. Digman
Michelle A. Digman University of California, Irvine
Karsten Rippe
Karsten Rippe German Cancer Research Center
Alán Aspuru-Guzik
Alán Aspuru-Guzik University of Toronto
Enrico Gratton
Enrico Gratton University of California, Irvine
Christine Ebel
Christine Ebel Grenoble Alpes University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a degree in Molecular Biology opens doors to many online learning opportunities and versatile career paths. When considering your options, it's important to seek programs with strong academic reputations. Many students prefer enrolling in non profit colleges because these institutions are more likely to focus on academic quality while offering affordable tuition.

If you are an active-duty service member or a veteran, look for veteran friendly online colleges that provide flexible schedules and dedicated support services for military students. These colleges help make distance learning more accessible while recognizing the unique needs of veterans.

Interested in branching out from the lab? Many graduates pursue related online master's degrees to broaden their knowledge and impact. Consider fields such as health, social policy, or psychology. Programs like social work online master's programs allow you to apply your scientific background to help communities directly.

For those eager to advance quickly, some accelerated masters psychology programs can be completed in less time, letting you specialize and enter the workforce sooner. These diverse educational pathways complement a foundation in molecular biology and offer broad career versatility.

Best Scientists Citing Peter H. von Hippel

Trending Scientists

Recently Published Articles