World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
9981
World Ranking
16181
National Ranking
6705

Overview

Martin L. Privalsky was affiliated with the University of California, Davis in the United States. Their research chiefly spanned several fields including Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broader areas, they contributed notably to subfields such as Genetics, Molecular Biology, Endocrinology, Diabetes and Metabolism, Physiology, and Cellular and Molecular Neuroscience.

The scientist's academic output encompassed multiple topics, highlighting a diverse research scope. Their main areas of focus included:

  • Estrogen and related hormone effects
  • Thyroid Disorders and Treatments
  • Retinoids in leukemia and cellular processes
  • Adipose Tissue and Metabolism
  • RNA Research and Splicing
  • Neurobiology and Insect Physiology Research
  • Invertebrate Immune Response Mechanisms

Martin L. Privalsky published research in several scientific venues. These included:

  • Molecular and Cellular Biology
  • PLoS ONE
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent papers demonstrated a focus on transcriptional regulation and alternative RNA splicing, topics closely linked to hormonal and metabolic processes. Notable publications include:

  • "Structure-Guided Approach to Relieving Transcriptional Repression in Resistance to Thyroid Hormone α" (2021), published in Molecular and Cellular Biology
  • "Specific ablation of the NCoR corepressor δ splice variant reveals alternative RNA splicing as a key regulator of hepatic metabolism" (2020), published in PLoS ONE
  • "Evidence from Amphioxus for acquisition of alternative mRNA splicing of NCoR corepressor after its duplication and divergence during vertebrate evolution" (2020), published in bioRxiv (Cold Spring Harbor Laboratory)

Throughout the research career, Martin L. Privalsky collaborated with several co-authors, including:

  • Beatriz Romartínez-Alonso
  • Maura Agostini
  • Heulyn Jones
  • Jayde A. McLellan
  • Disha Sood

The scientist's work contributed to better understanding molecular mechanisms related to hormone effects, metabolic regulation, and RNA splicing dynamics. Their publications indicated a multidisciplinary approach integrating genetics and molecular biology within both clinical and experimental contexts.

Best Publications

  • Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

    Hongwu Chen;Richard J Lin;Richard J Lin;R.Louis Schiltz;Debabrata Chakravarti

  • SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor α (RARα) and PLZF-RARα oncoproteins associated with acute promyelocytic leukemia

    Suk Hyun Hong;Gregory David;Chi Wai Wong;Anne Dejean

  • The role of corepressors in transcriptional regulation by nuclear hormone receptors

    Martin L. Privalsky

  • Identification of TRACs (T3 receptor-associating cofactors), a family of cofactors that associate with, and modulate the activity of, nuclear hormone receptors.

    Stephen Sande;Martin L. Privalsky

  • Thyroid hormone resistance syndrome manifests as an aberrant interaction between mutant T3 receptors and transcriptional corepressors

    Sunnie M. Yoh;V. K. K. Chatterjee;Martin L. Privalsky

  • The SMRT Corepressor Is Regulated by a MEK-1 Kinase Pathway: Inhibition of Corepressor Function Is Associated with SMRT Phosphorylation and Nuclear Export

    Suk-Hyun Hong;Martin L. Privalsky

  • Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy

    Rohit Anthony Sinha;Seo Hee You;Jin Zhou;Mobin M. Siddique

  • Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6.

    Chi Wai Wong;Martin L. Privalsky

  • Phosphorylation of PML by mitogen-activated protein kinases plays a key role in arsenic trioxide-mediated apoptosis

    Fumihiko Hayakawa;Martin L Privalsky

  • Transcriptional Repression by the SMRT-mSin3 Corepressor: Multiple Interactions, Multiple Mechanisms, and a Potential Role for TFIIB

    Chi Wai Wong;Martin L. Privalsky

  • Thyroid Hormones, T3 and T4, in the Brain

    Amy C. Schroeder;Martin L. Privalsky

  • Functional regulation of GATA-2 by acetylation.

    Fumihiko Hayakawa;Masayuki Towatari;Yukiyasu Ozawa;Akihiro Tomita

  • Site-specific mutagenesis of avian erythroblastosis virus: erb-B is required for oncogenicity

    Linda Sealy;Martin L. Privalsky;Giovanella Moscovici;Carlo Moscovici

  • v-erbA Oncogene Function in Neoplasia Correlates with Its Ability to Repress Retinoic Acid Receptor Action

    Mohammed Sharif;Martin L. Privalsky

  • Temporal Comparison of PBDEs, OH-PBDEs, PCBs, and OH-PCBs in the Serum of Second Trimester Pregnant Women Recruited from San Francisco General Hospital, California

    Ami R. Zota;Ami R. Zota;Linda Linderholm;Linda Linderholm;June Soo Park;Myrto Petreas

  • Competitive Cofactor Recruitment by Orphan Receptor Hepatocyte Nuclear Factor 4α1: Modulation by the F Domain

    Michael D. Ruse;Martin L. Privalsky;Frances M. Sladek

  • The product of the avian erythroblastosis virus erbB locus is a glycoprotein

    Martin L. Privalsky;Linda Sealy;J. Michael Bishop;John P. McGrath

  • SMRT and N-CoR Corepressors Are Regulated by Distinct Kinase Signaling Pathways

    Brian A. Jonas;Martin L. Privalsky

  • v-erbA and citral reduce the teratogenic effects of all-trans retinoic acid and retinol, respectively, in Xenopus embryogenesis.

    Timothy J. Schuh;Bonnie L. Hall;Joan Creech Kraft;Martin L. Privalsky

  • A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release.

    Benjamin C. Lin;Suk Hyun Hong;Sheryl Krig;Sunnie M. Yoh

Frequent Co-Authors

Tracey J. Woodruff
Tracey J. Woodruff Stanford University
William Bourguet
William Bourguet University of Montpellier
Scott A. Summers
Scott A. Summers University of Utah
Mitchell A. Lazar
Mitchell A. Lazar University of Pennsylvania
Frances M. Sladek
Frances M. Sladek University of California, Riverside
Giles E. Hardingham
Giles E. Hardingham University of Edinburgh
Hilmar Bading
Hilmar Bading Heidelberg University
Paul M. Yen
Paul M. Yen Duke University
Boon-Huat Bay
Boon-Huat Bay National University of Singapore
Hidehiko Saito
Hidehiko Saito Nagoya Medical Center

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