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Hidehiko Saito

Hidehiko Saito

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
34668
World Ranking
1815
National Ranking
101

Medicine

D-Index
95
Citations
34655
World Ranking
10033
National Ranking
279

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 1993 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Hidehiko Saito is affiliated with Nagoya Medical Center in Japan, specializing primarily in the field of Medicine. Their research contributions span several subfields, including Hematology, Social Psychology, Molecular Biology, Critical Care and Intensive Care Medicine, and Internal Medicine.

Their scientific work focuses on topics such as Blood Coagulation and Thrombosis Mechanisms, Trauma, Hemostasis, Coagulopathy, Resuscitation, Venous Thromboembolism Diagnosis and Management, Coagulation, Bradykinin, Polyphosphates, and Angioedema, Hemophilia Treatment and Research, Action Observation and Synchronization, and Hemispheric Asymmetry in Neuroscience.

They have published research in various scientific venues, including:

  • Research and Practice in Thrombosis and Haemostasis
  • International Journal of Hematology
  • Zenodo (CERN European Organization for Nuclear Research)
  • PubMed
  • Japanese Journal of Thrombosis and Hemostasis

Selected recent papers authored or co-authored by Hidehiko Saito include:

  • "Effects of thrombomodulin alfa on hemostatic parameters in disseminated intravascular coagulation: Post hoc analysis of a phase 3 randomized controlled trial," 2020, Research and Practice in Thrombosis and Haemostasis
  • "Unrecognized blood clotting factors," 2021, International Journal of Hematology
  • "Anatomical Study of the Right Forearm and Hand of One Western Gorilla (Gorilla gorilla) for Comparison with Humans with Respect to Motions of the Thumb and Fingers," 2021, Zenodo (CERN European Organization for Nuclear Research)
  • "A brief history of Aso International Meeting, Thrombosis, Hemostasis, and Vascular Science," 2021, Japanese Journal of Thrombosis and Hemostasis

Their frequent collaborators include Tetsuhito Kojima, Takashi Ito, Ikuro Maruyama, Shuji Shimazaki, and Yasuhiro Yamamoto.

In recognition of their scientific contributions, Hidehiko Saito was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 1993.

Best Publications

  • Enzymatic Methods for the Determination of Small Quantities of Isomeric Chondroitin Sulfates

    Hidehiko Saito;Tatsuya Yamagata;Sakaru Suzuki

  • Purification and Properties of Bacterial Chondroitinases and Chondrosulfatases

    Tatsuya Yamagata;Hidehiko Saito;Osami Habuchi;Sakaru Suzuki

  • Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.

    Yukiya Yamamoto;Hitoshi Kiyoi;Yasuyuki Nakano;Ritsuro Suzuki

  • Prognostic Implication of FLT3 and N- RAS Gene Mutations in Acute Myeloid Leukemia

    Hitoshi Kiyoi;Tomoki Naoe;Yasuyuki Nakano;Shohei Yokota

  • Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial

    H. Saito;I. Maruyama;S. Shimazaki;Y. Yamamoto

  • Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product.

    H Kiyoi;M Towatari;S Yokota;M Hamaguchi

  • Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression.

    Huanliang Liu;David Chao;Emi E. Nakayama;Hitomi Taguchi

  • Establishment of a Novel Human Megakaryoblastic Leukemia Cell Line, MEG-01, With Positive Philadelphia Chromosome

    Michinori Ogura;Yasuo Morishima;Ryuzo Ohno;Yukio Kato

  • Formation of Three Types of Disulfated Disaccharides from Chondroitin Sulfates by Chondroitinase Digestion

    Sakaru Suzuki;Sakaru Suzuki;Hidehiko Saito;Hidehiko Saito;Tatsuya Yamagata;Tatsuya Yamagata;Kimiko Anno;Kimiko Anno

  • Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain

    Hitoshi Kiyoi;Ryuzo Ohno;Ryuzo Ueda;Hidehiko Saito

  • Senile EBV+ B-cell lymphoproliferative disorders: a clinicopathologic study of 22 patients.

    Takashi Oyama;Koichi Ichimura;Ritsuro Suzuki;Junji Suzumiya

  • Hypermethylation of the p15INK4B gene in myelodysplastic syndromes.

    Toshiki Uchida;Tomohiro Kinoshita;Tomohiro Kinoshita;Hirokazu Nagai;Hirokazu Nagai;Yohsuke Nakahara;Yohsuke Nakahara

  • An Asian variant of intravascular large B-cell lymphoma: clinical, pathological and cytogenetic approaches to diffuse large B-cell lymphoma associated with haemophagocytic syndrome

    Takuhei Murase;Shigeo Nakamura;Kiyotaka Kawauchi;Hiromitsu Matsuzaki

  • Complete antithrombin deficiency in mice results in embryonic lethality

    Kazuhiro Ishiguro;Tetsuhito Kojima;Kenji Kadomatsu;Yukiko Nakayama

  • Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells.

    Takahiro Maeda;Masayuki Towatari;Hiroshi Kosugi;Hidehiko Saito

  • Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.

    Jean Louis Vincent;Bruno François;Igor Zabolotskikh;Mradul Daga

  • Increased incidence of thromboembolism in stage IV breast cancer patients treated with a five-drug chemotherapy regimen

    Lawrence Tim Goodnough;Hidehiko Saito;Andrea Manni;Paul K. Jones

  • Neointima formation in a restenosis model is suppressed in midkine-deficient mice.

    Mitsuru Horiba;Kenji Kadomatsu;Eishin Nakamura;Hisako Muramatsu

  • Analysis of Genetic Polymorphism in NQO1, GST-M1, GST-T1, and CYP3A4 in 469 Japanese Patients with Therapy-related Leukemia/Myelodysplastic Syndrome and de novo Acute Myeloid Leukemia

    Tomoki Naoe;Kunihiko Takeyama;Toshiya Yokozawa;Hitoshi Kiyoi

  • Congenital deficiency of alpha 2-plasmin inhibitor associated with severe hemorrhagic tendency.

    Nobuo Aoki;Hidehiko Saito;Tadashi Kamiya;Katsuo Koie

Frequent Co-Authors

Tetsuhito Kojima
Tetsuhito Kojima Nagoya University
Tomoki Naoe
Tomoki Naoe Nagoya University
Kaoru Shimokata
Kaoru Shimokata Nagoya University
Yoshinori Hasegawa
Yoshinori Hasegawa Nagoya University
Yasuo Morishima
Yasuo Morishima Aichi Medical University
Takashi Muramatsu
Takashi Muramatsu Nagoya University
Yoshiji Yamada
Yoshiji Yamada Mie University
Kenji Kadomatsu
Kenji Kadomatsu Nagoya University
Shonen Yoshida
Shonen Yoshida Nagoya University
Ryuzo Ueda
Ryuzo Ueda Nagoya University

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