World's Best Scientists 2026 revealed!
Laurence Calzone

Laurence Calzone

D-Index & Metrics

Engineering and Technology

D-Index
33
Citations
6003
World Ranking
9347
National Ranking
224

Overview

Laurence Calzone is affiliated with PSL University in France and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology. Their work spans significant subfields such as Molecular Biology, Computational Theory and Mathematics, Modeling and Simulation, Oncology, and Immunology.

The scientist's research topics include Gene Regulatory Network Analysis, Bioinformatics and Genomic Networks, Computational Drug Discovery Methods, Microbial Metabolic Engineering and Bioproduction, Mathematical Biology Tumor Growth, Single-cell and spatial transcriptomics, and Cell Image Analysis Techniques.

Calzone has published multiple papers, with notable recent contributions including:

  • Patient-specific Boolean models of signalling networks guide personalised treatments (2022, eLife)
  • Personalized logical models to investigate cancer response to BRAF treatments in melanomas and colorectal cancers (2021, PLoS Computational Biology)
  • PhysiBoSS 2.0: a sustainable integration of stochastic Boolean and agent-based modelling frameworks (2023, npj Systems Biology and Applications)
  • Setting the basis of best practices and standards for curation and annotation of logical models in biology-highlights of the [BC]2 2019 CoLoMoTo/SysMod Workshop (2020, Briefings in Bioinformatics)
  • BioSimulators: a central registry of simulation engines and services for recommending specific tools (2022, CU Scholar [University of Colorado Boulder])

Frequent coauthors in Calzone's scientific collaborations include Vincent Noël, Emmanuel Barillot, Andreï Zinovyev, Loïc Paulevé, and Aurélien Naldi.

Publication venues where Laurence Calzone regularly publishes comprise bioRxiv (Cold Spring Harbor Laboratory), PLoS Computational Biology, npj Systems Biology and Applications, Briefings in Bioinformatics, and Bioinformatics.

Best Publications

  • The Systems Biology Graphical Notation

    Nicolas Le Novere;Michael Hucka;Huaiyu Mi;Stuart Moodie

  • Integrative Analysis of Cell Cycle Control in Budding Yeast

    Katherine C. Chen;Laurence Calzone;Attila Csikasz-Nagy;Frederick R. Cross

  • BIOCHAM: an environment for modeling biological systems and formalizing experimental knowledge

    Laurence Calzone;François Fages;Sylvain Soliman

  • Mathematical Modelling of Cell-Fate Decision in Response to Death Receptor Engagement

    Laurence Calzone;Laurence Calzone;Laurence Calzone;Laurent Tournier;Laurent Tournier;Laurent Tournier;Simon Fourquet;Simon Fourquet;Simon Fourquet;Denis Thieffry;Denis Thieffry

  • Integrative modelling of the influence of MAPK network on cancer cell fate decision.

    Luca Grieco;Laurence Calzone;Isabelle Bernard-Pierrot;François Radvanyi

  • Computational Systems Biology of Cancer

    Emmanuel Barillot;Laurence Calzone;Philippe Hupe;Jean-Philippe Vert

  • A comprehensive modular map of molecular interactions in RB/E2F pathway

    Laurence Calzone;Laurence Calzone;Laurence Calzone;Amélie Gelay;Andrei Zinovyev;Andrei Zinovyev;Andrei Zinovyev;François Radvanyi

  • Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps

    Kuperstein I;Bonnet E;Bonnet E;Bonnet E;Nguyen Ha;Nguyen Ha;Nguyen Ha;Cohen D;Cohen D;Cohen D

  • Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration.

    David P. A. Cohen;Loredana Martignetti;Sylvie Robine;Emmanuel Barillot

  • Continuous time boolean modeling for biological signaling: application of Gillespie algorithm

    Gautier Stoll;Gautier Stoll;Gautier Stoll;Eric Viara;Emmanuel Barillot;Emmanuel Barillot;Emmanuel Barillot;Laurence Calzone;Laurence Calzone;Laurence Calzone

  • MaBoSS 2.0: an environment for stochastic Boolean modeling.

    Gautier Stoll;Barthélémy Caron;Eric Viara;Aurélien Dugourd

  • Machine learning biochemical networks from temporal logic properties

    Laurence Calzone;Nathalie Chabrier-Rivier;François Fages;Sylvain Soliman

  • Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.

    Antoine Forget;Antoine Forget;Loredana Martignetti;Stéphanie Puget;Laurence Calzone

  • PhysiBoSS: a multi-scale agent-based modelling framework integrating physical dimension and cell signalling.

    Gaëlle Letort;Arnau Montagud;Arnau Montagud;Gautier Stoll;Randy W. Heiland

  • Patient-specific Boolean models of signalling networks guide personalised treatments

    Unknown

  • BiNoM: a Cytoscape plugin for manipulating and analyzing biological networks

    Andrei Yu. Zinovyev;Eric Viara;Laurence Calzone;Emmanuel Barillot

  • The CoLoMoTo Interactive Notebook: Accessible and Reproducible Computational Analyses for Qualitative Biological Networks

    Aurélien Naldi;Céline Hernandez;Nicolas Levy;Gautier Stoll

  • Integrative multi-omics module network inference with Lemon-Tree.

    Eric Bonnet;Laurence Calzone;Tom Michoel

  • COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms.

    Marek Ostaszewski;Anna Niarakis;Anna Niarakis;Alexander Mazein;Inna Kuperstein;Inna Kuperstein

  • Personalization of Logical Models With Multi-Omics Data Allows Clinical Stratification of Patients.

    Jonas Béal;Arnau Montagud;Pauline Traynard;Emmanuel Barillot

  • BiNoM 2.0, a Cytoscape plugin for accessing and analyzing pathways using standard systems biology formats.

    Eric Bonnet;Eric Bonnet;Eric Bonnet;Laurence Calzone;Laurence Calzone;Laurence Calzone;Daniel Rovera;Daniel Rovera;Daniel Rovera;Gautier Stoll;Gautier Stoll;Gautier Stoll

  • Classification of gene signatures for their information value and functional redundancy.

    Laura Cantini;Laurence Calzone;Loredana Martignetti;Mattias Rydenfelt

  • Correction: Integrative Modelling of the Influence of MAPK Network on Cancer Cell Fate Decision

    Luca Grieco;Laurence Calzone;Isabelle Bernard-Pierrot;François Radvanyi

Frequent Co-Authors

Emmanuel Barillot
Emmanuel Barillot Institute Curie
Andrei Zinovyev
Andrei Zinovyev Institute Curie
Denis Thieffry
Denis Thieffry École Normale Supérieure
Peter J. Wild
Peter J. Wild Frankfurt Institute for Advanced Studies
Claudine Chaouiya
Claudine Chaouiya Aix-Marseille University
Julio Saez-Rodriguez
Julio Saez-Rodriguez Heidelberg University
Guido Kroemer
Guido Kroemer Université Paris Cité
Chris Sander
Chris Sander Harvard University
Tom C. Freeman
Tom C. Freeman University of Edinburgh

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