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Biology and Biochemistry

D-Index
81
Citations
28134
World Ranking
3828
National Ranking
282

Overview

Tom C. Freeman is affiliated with the University of Edinburgh in the United Kingdom. Their research spans several fields, primarily Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader areas, their work covers multiple subfields including Genetics, Epidemiology, Molecular Biology, Immunology, and Surgery.

Their research focuses on topics such as Inflammatory Bowel Disease, Microscopic Colitis, Helicobacter pylori-related gastroenterology studies, Bioinformatics and Genomic Networks, Immunodeficiency and Autoimmune Disorders, Psoriasis: Treatment and Pathogenesis, and Dermatology and Skin Diseases.

Freeman has published in a range of scientific venues, frequently appearing in:

  • Gastroenterology
  • Journal of Crohn's and Colitis
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of the Rheumatic Diseases
  • The American Journal of Gastroenterology

The scientist has collaborated extensively with several co-authors who have appeared in multiple publications alongside them. These frequent collaborators include Patrick Branigan, Daniel Cua, Matthew Germinaro, Bram Verstockt, and Bradford Mcrae.

Among their recent publications are:

  • "Identification of Complex Rumen Microbiome Interaction Within Diverse Functional Niches as Mechanisms Affecting the Variation of Methane Emissions in Bovine" (2020, Frontiers in Microbiology)
  • "Graphia: A platform for the graph-based visualisation and analysis of high dimensional data" (2022, PLoS Computational Biology)
  • "Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging" (2021, Nature Aging)
  • "The transcriptional signature associated with human motile cilia" (2020, Scientific Reports)
  • "Multiclonal human origin and global expansion of an endemic bacterial pathogen of livestock" (2022, Proceedings of the National Academy of Sciences)

Best Publications

  • Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

    Jia Xue;Susanne V. Schmidt;Jil Sander;Astrid Draffehn

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Microglial brain region−dependent diversity and selective regional sensitivities to aging

    Kathleen Grabert;Tom Michoel;Michail H. Karavolos;Sara M. R. Clohisey

  • Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress.

    S. Prabakaran;S. Prabakaran;J. E. Swatton;J. E. Swatton;M. M. Ryan;M. M. Ryan;S. J. Huffaker;S. J. Huffaker

  • The Systems Biology Graphical Notation

    Nicolas Le Novere;Michael Hucka;Huaiyu Mi;Stuart Moodie

  • Oligodendrocyte dysfunction in schizophrenia and bipolar disorder.

    Dmitri Tkachev;Michael L Mimmack;Michael L Mimmack;Margaret M Ryan;Margaret M Ryan;Matt Wayland

  • Gateways to the FANTOM5 promoter level mammalian expression atlas

    Marina Lizio;Jayson Harshbarger;Hisashi Shimoji;Jessica Severin

  • Somatic retrotransposition alters the genetic landscape of the human brain

    J. Kenneth Baillie;Mark W. Barnett;Kyle R. Upton;Daniel J. Gerhardt

  • Tissue distribution of adenosine receptor mRNAs in the rat

    Alistair K. Dixon;Amelie K. Gubitz;Dalip J.S. Sirinathsinghji;Peter J. Richardson

  • Fulminant Jejuno-Ileitis following Ablation of Enteric Glia in Adult Transgenic Mice

    Toby G Bush;Tor C Savidge;Tor C Savidge;Tom C Freeman;Hilary J Cox

  • Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

    Erik Arner;Carsten O. Daub;Kristoffer Vitting-Seerup;Robin Andersson

  • The measurement of forgiveness: Preliminary research.

    Paul A. Mauger;Jacqueline E. Perry;Tom Freeman;Dianne C. Grove

  • Network visualization and analysis of gene expression data using BioLayout Express 3D

    Athanasios Theocharidis;Stjin van Dongen;Anton J Enright;Tom C Freeman

  • An expression atlas of human primary cells: inference of gene function from coexpression networks

    Neil A Mabbott;J Kenneth Baillie;Helen Brown;Tom C Freeman

  • The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9

    Marc-André Wurbel;Jean-Marc Philippe;Catherine Nguyen;Genevieve Victorero

  • Orientation Discrimination Performance Is Predicted by GABA Concentration and Gamma Oscillation Frequency in Human Primary Visual Cortex

    Richard Anthony Edward Edden;Suresh Daniel Muthukumaraswamy;Thomas Charles Augustus Freeman;Krish Devi Singh

  • Bovine Host Genetic Variation Influences Rumen Microbial Methane Production with Best Selection Criterion for Low Methane Emitting and Efficiently Feed Converting Hosts Based on Metagenomic Gene Abundance

    Rainer Roehe;Richard J. Dewhurst;Carol-Anne Duthie;John A. Rooke

  • Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

    Richard W E Clarkson;Matthew T Wayland;Jennifer Lee;Tom Freeman

  • Molecular Signatures Distinguish Human Central Memory from Effector Memory CD8 T Cell Subsets

    Tim Willinger;Tom Freeman;Hitoshi Hasegawa;Andrew J. McMichael

  • Construction, Visualisation, and Clustering of Transcription Networks from Microarray Expression Data

    Tom C A Freeman;Leon Goldovsky;Markus Brosch;Stijn van Dongen

Frequent Co-Authors

David A. Hume
David A. Hume University of Queensland
Neil A. Mabbott
Neil A. Mabbott University of Edinburgh
Jean Manson
Jean Manson University of Edinburgh
Peter Ghazal
Peter Ghazal Cardiff University
Alan Archibald
Alan Archibald University of Edinburgh
Anton J. Enright
Anton J. Enright University of Cambridge
Alistair R. R. Forrest
Alistair R. R. Forrest Harry Perkins Institute of Medical Research
Elizabeth A. Campbell
Elizabeth A. Campbell Rockefeller University

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