World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
28732
World Ranking
4019
National Ranking
1986

Overview

Holly Van Remmen is affiliated with the Oklahoma Medical Research Foundation in the United States. Their research primarily focuses on areas within medicine and biochemistry, genetics, and molecular biology. The scientist's work spans numerous subfields including molecular biology, physiology, rehabilitation, cellular and molecular neuroscience, and neurology.

The research topics addressed by Holly Van Remmen extensively cover muscle physiology and disorders, adipose tissue and metabolism, mitochondrial function and pathology, exercise and physiological responses, amyotrophic lateral sclerosis research, muscle metabolism and nutrition, and nutrition and health in aging.

Recent publications by the scientist include:

  • Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo, 2022, Nature Metabolism
  • The SarcoEndoplasmic Reticulum Calcium ATPase (SERCA) pump: a potential target for intervention in aging and skeletal muscle pathologies, 2021, Skeletal Muscle
  • SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer, 2021, Nature Communications
  • Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia, 2021, Journal of Cachexia Sarcopenia and Muscle
  • Neuron-specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice, 2020, Aging Cell

Frequent co-authors collaborating with Holly Van Remmen include:

  • Jacob L. Brown
  • Arlan Richardson
  • Rojina Ranjit
  • Hongyang Xu
  • Benjamin F. Miller

Key publication venues where the scientist has published multiple times are:

  • Free Radical Biology and Medicine
  • GeroScience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Redox Biology
  • Journal of Cachexia Sarcopenia and Muscle

Best Publications

  • Extension of murine life span by overexpression of catalase targeted to mitochondria.

    Samuel E. Schriner;Nancy J. Linford;George M. Martin;Piper Treuting

  • Trends in oxidative aging theories

    Florian L. Muller;Michael S. Lustgarten;Youngmok Jang;Arlan Richardson;Arlan Richardson

  • Complex III Releases Superoxide to Both Sides of the Inner Mitochondrial Membrane

    Florian L. Muller;Yuhong Liu;Holly Van Remmen

  • Does oxidative damage to DNA increase with age

    M. L. Hamilton;H. Van Remmen;J. A. Drake;H. Yang

  • Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

    Holly Van Remmen;Holly Van Remmen;Yuji Ikeno;Yuji Ikeno;Michelle Hamilton;Mohammad Pahlavani

  • THE SELENOPROTEIN GPX4 IS ESSENTIAL FOR MOUSE DEVELOPMENT AND PROTECTS FROM RADIATION AND OXIDATIVE DAMAGE INSULTS

    Levi J Yant;Qitao Ran;Lin Rao;Holly Van Remmen

  • Is the oxidative stress theory of aging dead

    Viviana I. Pérez;Alex Bokov;Holly Van Remmen;James Mele

  • Insulin resistance is a cellular antioxidant defense mechanism

    Kyle L Hoehn;Adam B Salmon;Cordula Hohnen-Behrens;Nigel Turner

  • Increased Oxidative Damage Is Correlated to Altered Mitochondrial Function in Heterozygous Manganese Superoxide Dismutase Knockout Mice

    Melissa D. Williams;Holly Van Remmen;Holly Van Remmen;Craig C. Conrad;Craig C. Conrad;Ting Ting Huang

  • Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy

    Florian L. Muller;Wook Song;Yuhong Liu;Asish Chaudhuri;Asish Chaudhuri

  • Methionine oxidation and aging

    Earl R. Stadtman;Holly Van Remmen;Arlan Richardson;Nancy B. Wehr

  • High oxidative damage levels in the longest-living rodent, the naked mole-rat

    Blazej Andziak;Timothy P. O'Connor;Wenbo Qi;Eric M. Dewaal

  • The overexpression of major antioxidant enzymes does not extend the lifespan of mice

    Viviana I. Pérez;Holly Van Remmen;Alex Bokov;Charles J. Epstein

  • Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production.

    Florian L. Muller;Wook Song;Wook Song;Youngmok C. Jang;Yuhong Liu

  • Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models?

    JennaLynn Styskal;Holly Van Remmen;Holly Van Remmen;Arlan Richardson;Arlan Richardson;Adam B. Salmon;Adam B. Salmon

  • Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration

    Youngmok C. Jang;Michael S. Lustgarten;Yuhong Liu;Florian L. Muller

  • Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis

    Holly Van Remmen;Holly Van Remmen;Melissa D. Williams;Zhongmao Guo;Larry Estlack

  • Rapamycin extends life and health in C57BL/6 mice.

    Yiqiang Zhang;Alex Bokov;Jonathan A Gelfond;Vanessa Soto

  • Transgenic Mice Overexpressing Glutathione Peroxidase 4 Are Protected against Oxidative Stress-induced Apoptosis

    Qitao Ran;Hanyu Liang;Minjun Gu;Wenbo Qi

  • The in vivo gene expression signature of oxidative stress

    Eun Soo Han;Florian L. Muller;Viviana I. Pérez;Wenbo Qi

Frequent Co-Authors

Arlan Richardson
Arlan Richardson University of Oklahoma Health Sciences Center
Florian L. Muller
Florian L. Muller The University of Texas MD Anderson Cancer Center
Susan V. Brooks
Susan V. Brooks University of Michigan–Ann Arbor
Malcolm J. Jackson
Malcolm J. Jackson University of Liverpool
Michael Kinter
Michael Kinter Oklahoma Medical Research Foundation
Charles J. Epstein
Charles J. Epstein University of California, San Francisco
Jonathan D. Wren
Jonathan D. Wren Oklahoma Medical Research Foundation
Jan Vijg
Jan Vijg Albert Einstein College of Medicine
John A. Faulkner
John A. Faulkner University of Michigan–Ann Arbor
L. Jackson Roberts
L. Jackson Roberts Vanderbilt University

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