World's Best Scientists 2026 revealed!
Takahiko Shimizu

Takahiko Shimizu

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10412
World Ranking
13966
National Ranking
984

Takahiko Shimizu publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Takahiko Shimizu sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 186 publications — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Takahiko Shimizu D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Takahiko Shimizu sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 57 D-Index — 31st percentile

31% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Takahiko Shimizu is affiliated with Chiba University in Japan, with a research focus rooted primarily in Medicine and Biochemistry, Genetics, and Molecular Biology. Their work spans various subfields including Molecular Biology, Physiology, Pharmacology, Public Health, Environmental and Occupational Health, and Biochemistry.

The scientist's recent research contributions feature investigations into mitochondrial function and oxidative stress, reflecting an emphasis on cellular bioenergetics and disease pathology. Notable recent papers include:

  • SOD2 deficiency in cardiomyocytes defines defective mitochondrial bioenergetics as a cause of lethal dilated cardiomyopathy (2020, Redox Biology)
  • SOD2 in skeletal muscle: New insights from an inducible deletion model (2021, Redox Biology)
  • Short-term resveratrol treatment restored the quality of oocytes in aging mice (2022, Aging)
  • Neuron-specific mitochondrial oxidative stress results in epilepsy, glucose dysregulation and a striking astrocyte response (2021, Neurobiology of Disease)
  • SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential (2024, Redox Biology)

Their research topics cover a range of areas including:

  • Alzheimer's disease research and treatments
  • Mitochondrial Function and Pathology
  • Cholinesterase and Neurodegenerative Diseases
  • Adipose Tissue and Metabolism
  • Neuroscience and Neuropharmacology Research
  • Advanced biosensing and bioanalysis techniques
  • ATP Synthase and ATPases Research

Frequent publication venues for Takahiko Shimizu include:

  • Redox Biology
  • International Journal of Molecular Sciences
  • European Journal of Pharmacology
  • Antioxidants
  • Geriatrics and gerontology international / Geriatrics & gerontology international

Collaboration has been a consistent aspect of their work, with frequent coauthors including:

  • Shuichi Shibuya
  • Naotaka Izuo
  • Kazuhiro Irie
  • Kazuma Murakami
  • Kenji Watanabe

Throughout their career, Takahiko Shimizu has advanced the understanding of oxidative stress mechanisms and mitochondrial dysfunction as they relate to degenerative diseases and pharmacological interventions.

Best Publications

  • Inhibition of autophagy in the heart induces age-related cardiomyopathy.

    Manabu Taneike;Osamu Yamaguchi;Atsuko Nakai;Shungo Hikoso

  • Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration.

    Yutaka Imamura;Setsuko Noda;Kouhei Hashizume;Kei Shinoda

  • Neurotoxicity and Physicochemical Properties of Aβ Mutant Peptides from Cerebral Amyloid Angiopathy: IMPLICATION FOR THE PATHOGENESIS OF CEREBRAL AMYLOID ANGIOPATHY AND ALZHEIMER'S DISEASE

    Kazuma Murakami;Kazuhiro Irie;Akira Morimoto;Hajime Ohigashi

  • SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease.

    Kazuma Murakami;Nakaba Murata;Yoshihiro Noda;Shoichi Tahara

  • Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans.

    Juewon Kim;Mayumi Takahashi;Takahiko Shimizu;Takuji Shirasawa

  • Oxidative stress causes heart failure with impaired mitochondrial respiration.

    Hidetoshi Nojiri;Takahiko Shimizu;Masabumi Funakoshi;Osamu Yamaguchi

  • Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells.

    Yasutaka Ikeda;Shinji Tsuji;Akira Satoh;Masaharu Ishikura

  • Analysis of the Secondary Structure of β-Amyloid (Aβ42) Fibrils by Systematic Proline Replacement

    Akira Morimoto;Kazuhiro Irie;Kazuma Murakami;Yuichi Masuda

  • Formation and Stabilization Model of the 42-mer Aβ Radical: Implications for the Long-Lasting Oxidative Stress in Alzheimer's Disease

    Kazuma Murakami;Kazuhiro Irie;Hajime Ohigashi;Hideyuki Hara

  • Biological Significance of Isoaspartate and Its Repair System

    Takahiko Shimizu;Yasuji Matsuoka;Takuji Shirasawa

  • Cytoplasmic superoxide causes bone fragility owing to low‐turnover osteoporosis and impaired collagen cross‐linking

    Hidetoshi Nojiri;Yoshitomo Saita;Daichi Morikawa;Keiji Kobayashi

  • Synthesis, aggregation, neurotoxicity, and secondary structure of various Aβ1–42 mutants of familial Alzheimer's disease at positions 21–23

    Kazuma Murakami;Kazuhiro Irie;Akira Morimoto;Hajime Ohigashi

  • CuZn-SOD Deficiency Causes ApoB Degradation and Induces Hepatic Lipid Accumulation by Impaired Lipoprotein Secretion in Mice

    Satoshi Uchiyama;Takahiko Shimizu;Takuji Shirasawa

  • Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration.

    Masato Koike;Hidetoshi Nojiri;Yusuke Ozawa;Kenji Watanabe

  • Retinal Dysfunction and Progressive Retinal Cell Death in SOD1-Deficient Mice

    Kouhei Hashizume;Manabu Hirasawa;Yutaka Imamura;Setsuko Noda

  • Identification of Physiological and Toxic Conformations in Aβ42 Aggregates

    Yuichi Masuda;Satoko Uemura;Ryutaro Ohashi;Azusa Nakanishi

  • Structure of β-amyloid fibrils and its relevance to their neurotoxicity: Implications for the pathogenesis of Alzheimer’s disease

    Kazuhiro Irie;Kazuma Murakami;Yuichi Masuda;Akira Morimoto

  • Isoaspartate formation at position 23 of amyloid beta peptide enhanced fibril formation and deposited onto senile plaques and vascular amyloids in Alzheimer's disease.

    Takahiko Shimizu;Hiroyuki Fukuda;Shigeo Murayama;Naoki Izumiyama

  • Copper/Zinc Superoxide Dismutase Insufficiency Impairs Progesterone Secretion and Fertility in Female Mice

    Yoshihiro Noda;Kuniaki Ota;Takuji Shirasawa;Takahiko Shimizu

  • Oxidative stress in skeletal muscle causes severe disturbance of exercise activity without muscle atrophy

    Hirotomo Kuwahara;Tetsuro Horie;Shin Ishikawa;Chizuru Tsuda

Frequent Co-Authors

Takuji Shirasawa
Takuji Shirasawa Shirasawa Anti-Aging Medical Institute
Kazuo Tsubota
Kazuo Tsubota Keio University
Murat Dogru
Murat Dogru Keio University
Hajime Ohigashi
Hajime Ohigashi Kyoto University
Arlan Richardson
Arlan Richardson University of Oklahoma Health Sciences Center
Toshifumi Takao
Toshifumi Takao Osaka University
Holly Van Remmen
Holly Van Remmen Oklahoma Medical Research Foundation
Jun Shimazaki
Jun Shimazaki Tokyo Dental College
Masahiro Maeda
Masahiro Maeda Osaka University
Florian L. Muller
Florian L. Muller The University of Texas MD Anderson Cancer Center

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