What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His primary scientific interests are in Molecular biology, Biochemistry, Superoxide dismutase, Endocrinology and Internal medicine.
The study incorporates disciplines such as Neurotoxicity, Mutation, Mutant, Knockout mouse and Cerebral amyloid angiopathy in addition to Molecular biology.
SOD2 is closely connected to Genetically modified mouse in his research, which is encompassed under the umbrella topic of Knockout mouse.
His Superoxide dismutase study is related to the wider topic of Oxidative stress.
His Oxidative stress research includes themes of Lipofuscin, Senescence, Paraquat and Caenorhabditis elegans.
Takuji Shirasawa has researched Endocrinology in several fields, including Superoxide and Mitochondrion.
His most cited work include:
- Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1. (303 citations)
- Inhibition of autophagy in the heart induces age-related cardiomyopathy. (286 citations)
- μ1B, a novel adaptor medium chain expressed in polarized epithelial cells1 (221 citations)
What are the main themes of his work throughout his whole career to date?
Molecular biology, Internal medicine, Endocrinology, Biochemistry and Cell biology are his primary areas of study.
The concepts of his Molecular biology study are interwoven with issues in Genetics, Mutant, Complementary DNA, Peptide sequence and Exon.
His Endocrinology research integrates issues from Gene expression and Neuron.
His study in Biochemistry is interdisciplinary in nature, drawing from both Neurotoxicity and In vivo.
His Cell biology research includes elements of Immunology, Embryonic stem cell, Downregulation and upregulation and Transgene.
The Oxidative stress study combines topics in areas such as Antioxidant and Pathogenesis, Pathology.
He most often published in these fields:
- Molecular biology (25.81%)
- Internal medicine (23.87%)
- Endocrinology (21.94%)
What were the highlights of his more recent work (between 2013-2020)?
- Endocrinology (21.94%)
- Internal medicine (23.87%)
- Coenzyme Q – cytochrome c reductase (6.45%)
In recent papers he was focusing on the following fields of study:
His main research concerns Endocrinology, Internal medicine, Coenzyme Q – cytochrome c reductase, Cell biology and Mitochondrion.
His biological study spans a wide range of topics, including Superoxide and CYP17A1.
His Coenzyme Q – cytochrome c reductase research is under the purview of Biochemistry.
His Biochemistry study often links to related topics such as Respiratory system.
He has included themes like Molecular biology and Caenorhabditis elegans, Gene in his Cell biology study.
Specifically, his work in Oxidative stress is concerned with the study of Superoxide dismutase.
Between 2013 and 2020, his most popular works were:
- Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration. (65 citations)
- Mitochondrial superoxide in osteocytes perturbs canalicular networks in the setting of age-related osteoporosis. (39 citations)
- Aging-induced changes in sex-steroidogenic enzymes and sex-steroid receptors in the cortex, hypothalamus and cerebellum (22 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
Takuji Shirasawa focuses on Endocrinology, Internal medicine, SOD2, Superoxide and Superoxide dismutase.
His Hypothalamus and Cerebral cortex study in the realm of Endocrinology interacts with subjects such as Androgen receptor and Estrogen receptor alpha.
His Internal medicine research is multidisciplinary, incorporating elements of Coenzyme Q – cytochrome c reductase, Biochemistry and CYP17A1.
His work deals with themes such as Paraquat and Bone cell, which intersect with Superoxide.
His research integrates issues of Molecular biology and Mitochondrion, Cell biology in his study of Superoxide dismutase.
As part of one scientific family, Takuji Shirasawa deals mainly with the area of Molecular biology, narrowing it down to issues related to the Periodic acid–Schiff stain, and often Goblet cell and Conjunctiva.
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