Hiroshi Tokumitsu

Overview

Best Publications

• KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II

  Hiroshi Tokumitsu;Takashi Chijiwa;Masatoshi Hagiwara;Akihiro Mizutani

  936
  Citations

• Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

  Shigetoshi Yano;Hiroshi Tokumitsu;Thomas R. Soderling

  756
  Citations

• Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity

  Gary A. Wayman;Yong-Seok Lee;Hiroshi Tokumitsu;Alcino J. Silva

  680
  Citations

• STO-609, a Specific Inhibitor of the Ca2+/Calmodulin-dependent Protein Kinase Kinase

  Hiroshi Tokumitsu;Hiroyuki Inuzuka;Yumi Ishikawa;Masahiko Ikeda

  402
  Citations

• Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade

  Hervé Enslen;Hiroshi Tokumitsu;Philip J.S. Stork;Roger J. Davis

  375
  Citations

• Characterization of a Ca2+/calmodulin-dependent protein kinase cascade: Molecular cloning and expression of calcium/calmodulin-dependent protein kinase kinase

  Hiroshi Tokumitsu;Hervé Enslen;Thomas R. Soderling

  325
  Citations

• A novel target recognition revealed by calmodulin in complex with Ca2+-calmodulin-dependent kinase kinase.

  Masanori Osawa;Hiroshi Tokumitsu;Mark B. Swindells;Hiroyuki Kurihara

  316
  Citations

• NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus.

  Esteban S. Masuda;Yoshiyuki Naito;Hiroshi Tokumitsu;Dave Campbell

  309
  Citations

• Regulation of Axonal Extension and Growth Cone Motility by Calmodulin-Dependent Protein Kinase I

  Gary A. Wayman;Stefanie Kaech;Wilmon F. Grant;Monika Davare

  237
  Citations

• Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase.

  Hiroshi Tokumitsu;Debra A. Brickey;John Glod;Hiroyoshi Hidaka

  191
  Citations

• Requirements for Calcium and Calmodulin in the Calmodulin Kinase Activation Cascade

  Hiroshi Tokumitsu;Thomas R. Soderling

  176
  Citations

• Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51.

  Jin Yan;Hidehito Kuroyanagi;Asato Kuroiwa;Yo Ichi Matsuda

  175
  Citations

• Analysis of CaM-kinase Signaling in Cells

  Gary A. Wayman;Hiroshi Tokumitsu;Monika A. Davare;Thomas R. Soderling

  163
  Citations

• A CaMK cascade activates CRE-mediated transcription in neurons of Caenorhabditis elegans.

  Yoshishige Kimura;Ethan E. Corcoran;Koh Eto;Keiko Gengyo-Ando

  161
  Citations

• The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT.

  E. S. Masuda;H. Tokumitsu;A. Tsuboi;J. Shlomai

  157
  Citations

• Target-induced conformational adaptation of calmodulin revealed by the crystal structure of a complex with nematode Ca(2+)/calmodulin-dependent kinase kinase peptide

  Hirofumi Kurokawa;Masanori Osawa;Hiroyuki Kurihara;Naoko Katayama

  131
  Citations

• A calcyclin-associated protein is a newly identified member of the Ca2+/phospholipid-binding proteins, annexin family.

  H Tokumitsu;A Mizutani;H Minami;R Kobayashi

  131
  Citations

• Inhibitory cross-talk by cAMP kinase on the calmodulin-dependent protein kinase cascade.

  Gary A. Wayman;Hiroshi Tokumitsu;Thomas R. Soderling

  130
  Citations

• Phosphorylation of CREB by CaM-Kinase IV Activated by CaM-Kinase IV Kinase

  Hervé Enslen;Hiroshi Tokumitsu;T. R. Soderling

  113
  Citations

• Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity (DOI:10.1016/j.neuron.2008.08.021)

  Gary A. Wayman;Yong Seok Lee;Hiroshi Tokumitsu;Alcino J. Silva

  18
  Citations