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D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
21789
World Ranking
4108
National Ranking
2018

Overview

John A. Faulkner is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans several interconnected fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience. The work covers a number of specialized subfields such as Molecular Biology, Endocrine and Autonomic Systems, Cell Biology, Infectious Diseases, and Cognitive Neuroscience.

The main topics of their research involve Circadian rhythm and melatonin, Sleep and Wakefulness Research, Proteoglycans and glycosaminoglycans research, Fibroblast Growth Factor Research, Platelet Disorders and Treatments, and investigations related to COVID-19 clinical research and SARS-CoV-2.

Frequent publication venues for their work include Scientific Reports, Frontiers in Molecular Biosciences, Proceedings of the National Academy of Sciences, Behavioural Brain Research, and Frontiers in Cellular Neuroscience.

Recent papers authored or co-authored by John A. Faulkner include:

  • Heparan Sulfate Facilitates Spike Protein-Mediated SARS-CoV-2 Host Cell Invasion and Contributes to Increased Infection of SARS-CoV-2 G614 Mutant and in Lung Cancer (2021), Frontiers in Molecular Biosciences
  • Wake-sleep cycles are severely disrupted by diseases affecting cytoplasmic homeostasis (2020), Proceedings of the National Academy of Sciences
  • Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis (2022), Scientific Reports
  • Circadian rhythm shifts and alcohol access in adolescence synergistically increase alcohol preference and intake in adulthood in male C57BL/6 mice (2022), Behavioural Brain Research
  • Inhibition of casein kinase 1 δ/ε improves cognitive performance in adult C57BL/6J mice (2021), Scientific Reports

John A. Faulkner has collaborated frequently with several coauthors, including:

  • Xuehong Song
  • Lianchun Wang
  • Joshua J. Gamsby
  • Hannah Justin
  • Heather Mahoney

The research conducted by John A. Faulkner involves a multidisciplinary approach to understanding molecular and cellular processes underlying circadian rhythms, infectious diseases, and neurological functions. The studies on SARS-CoV-2 mechanisms contribute to the growing body of knowledge on COVID-19, with an emphasis on viral entry facilitated by heparan sulfate and implications for cancer-affected tissues.

Work on circadian biology intersects with behavioral neuroscience, examining how factors such as alcohol consumption during adolescence can influence adult behavior and how disruption in wake-sleep cycles relates to systemic disease. Faulkner's investigations into cognitive performance involve molecular targets like casein kinase, which are important in neural regulation and therapeutic potential.

Best Publications

  • Contractile properties of skeletal muscles from young, adult and aged mice.

    S V Brooks;J A Faulkner

  • AGE-RELATED CHANGES IN THE STRUCTURE AND FUNCTION OF SKELETAL MUSCLES

    John A Faulkner;Lisa M Larkin;Dennis R Claflin;Susan V Brooks

  • Skeletal muscle weakness in old age : Underlying mechanisms

    Susan V. Brooks;John A. Faulkner

  • The regeneration of skeletal muscle fibers following injury: a review.

    Bruce M. Carlson;John A. Faulkner

  • Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy

    Florian L. Muller;Wook Song;Yuhong Liu;Asish Chaudhuri;Asish Chaudhuri

  • Injury to Skeletal Muscle Fibers During Contractions: Conditions of Occurrence and Prevention

    John A Faulkner;Susan V Brooks;Julie A Opiteck

  • Progressive Muscular Dystrophy in α-Sarcoglycan–deficient Mice

    Franck Duclos;Volker Straub;Steven A. Moore;David P. Venzke

  • Injury to muscle fibres after single stretches of passive and maximally stimulated muscles in mice.

    S V Brooks;E Zerba;J A Faulkner

  • Free radical injury to skeletal muscles of young, adult, and old mice

    E. Zerba;T. E. Komorowski;J. A. Faulkner

  • Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma

    Jeffrey S. Chamberlain;Joseph Metzger;Morayma Reyes;De Wayne Townsend

  • Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity

    Gregory A. Cox;Neil M. Cole;Kiichiro Matsumura;Stephanie F. Phelps

  • Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice

    Stephanie F. Phelps;Michael A. Hauser;Neil M. Cole;Jill A. Rafael

  • Force and power output of fast and slow skeletal muscles from mdx mice 6‐28 months old

    Gordon S. Lynch;Richard T. Hinkle;Jeffrey S. Chamberlain;Susan V. Brooks

  • Sarcolemma-localized nNOS is required to maintain activity after mild exercise

    Yvonne M. Kobayashi;Erik P. Rader;Robert W. Crawford;Nikhil K. Iyengar

  • Contraction-induced injury: recovery of skeletal muscles in young and old mice.

    S. V. Brooks;J. A. Faulkner

  • Overexpression of HSP70 in mouse skeletal muscle protects against muscle damage and age-related muscle dysfunction.

    Anne McArdle;Wolfgang H. Dillmann;Ruben Mestril;John A. Faulkner

  • Excitability and contractility of skeletal muscle engineered from primary cultures and cell lines

    Robert G. Dennis;Paul E. Kosnik;Mark E. Gilbert;John A. Faulkner

  • Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging

    Abdellah Mansouri;Florian L. Muller;Yuhong Liu;Rainer Ng

  • Muscle atrophy and weakness with aging: contraction-induced injury as an underlying mechanism.

    J A Faulkner;S V Brooks;E Zerba

  • Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain.

    Gregory E. Crawford;John A. Faulkner;Rachelle H. Crosbie;Kevin P. Campbell

Frequent Co-Authors

Susan V. Brooks
Susan V. Brooks University of Michigan–Ann Arbor
Bruce M. Carlson
Bruce M. Carlson University of Michigan–Ann Arbor
Jeffrey S. Chamberlain
Jeffrey S. Chamberlain University of Washington
Arlan Richardson
Arlan Richardson University of Oklahoma Health Sciences Center
Malcolm J. Jackson
Malcolm J. Jackson University of Liverpool
Kevin P. Campbell
Kevin P. Campbell University of Iowa
Holly Van Remmen
Holly Van Remmen Oklahoma Medical Research Foundation
Steven A. Moore
Steven A. Moore University of Iowa
Richard A. Miller
Richard A. Miller University of Michigan–Ann Arbor
James A. McNamara
James A. McNamara University of Michigan–Ann Arbor

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