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Molecular Biology

D-Index
51
Citations
8774
World Ranking
2509
National Ranking
1239

Overview

Yongping Yue is affiliated with the University of Missouri in the United States. Their research predominantly spans the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Within these fields, key subfields include Molecular Biology, Genetics, Cardiology and Cardiovascular Medicine, Physiology, and Cell Biology.

The scientist's work covers several main topics, such as:

  • Muscle Physiology and Disorders
  • Virus-based Gene Therapy Research
  • Viral Infections and Immunology Research
  • Adipose Tissue and Metabolism
  • CRISPR and Genetic Engineering
  • Muscle Metabolism and Nutrition
  • Cytomegalovirus and Herpesvirus Research

Yue has contributed to multiple peer-reviewed papers, several of which include:

  • Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models, 2021, Nature Communications
  • Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice, 2020, eLife
  • Single SERCA2a Therapy Ameliorated Dilated Cardiomyopathy for 18 Months in a Mouse Model of Duchenne Muscular Dystrophy, 2020, Molecular Therapy
  • Rational engineering of a functional CpG-free ITR for AAV gene therapy, 2021, Gene Therapy
  • High-Resolution Histological Landscape of AAV DNA Distribution in Cellular Compartments and Tissues following Local and Systemic Injection, 2020, Molecular Therapy - Methods & Clinical Development

The most frequent publication venues where Yue has published include:

  • Molecular Therapy - Methods & Clinical Development
  • Human Gene Therapy
  • Disease Models & Mechanisms
  • Diabetes
  • Nature Communications

Yue regularly collaborates with several co-authors. Frequent collaborators include Dongsheng Duan, Xiufang Pan, Gang Yao, Chady H. Hakim, and Nalinda B. Wasala.

Best Publications

  • Circular Intermediates of Recombinant Adeno-Associated Virus Have Defined Structural Characteristics Responsible for Long-Term Episomal Persistence in Muscle Tissue

    Dongsheng Duan;Prerna Sharma;Jusan Yang;Yongping Yue

  • Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.

    Dongsheng Duan;Yongping Yue;Ziying Yan;Jusan Yang

  • Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy

    Yi Lai;Gail D. Thomas;Yongping Yue;Hsiao T. Yang

  • Dynamin Is Required for Recombinant Adeno-Associated Virus Type 2 Infection

    Dongsheng Duan;Qiang Li;Aimee W. Kao;Yongping Yue

  • Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison.

    Dongsheng Duan;Yongping Yue;John F. Engelhardt

  • A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation.

    Dongsheng Duan;Yongping Yue;Ziying Yan;John F. Engelhardt

  • Efficient in vivo gene expression by trans -splicing adeno-associated viral vectors

    Yi Lai;Yongping Yue;Mingju Liu;Arkasubhra Ghosh

  • Polarity Influences the Efficiency of Recombinant Adenoassociated Virus Infection in Differentiated Airway Epithelia

    Dongsheng Duan;Yongping Yue;Ziying Yan;Paul B. McCray

  • Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury.

    Mingju Liu;Yongping Yue;Scott Q. Harper;Robert W. Grange

  • Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration.

    B Bostick;A Ghosh;Y Yue;C Long

  • Evidence for the Failure of Adeno-associated Virus Serotype 5 to Package a Viral Genome ≥8.2 kb

    Yi Lai;Yongping Yue;Dongsheng Duan

  • A Single Intravenous Injection of Adeno-associated Virus Serotype-9 Leads to Whole Body Skeletal Muscle Transduction in Dogs

    Yongping Yue;Arkasubhra Ghosh;Chun Long;Brian Bostick

  • Microdystrophin Gene Therapy of Cardiomyopathy Restores Dystrophin-Glycoprotein Complex and Improves Sarcolemma Integrity in the Mdx Mouse Heart

    Yongping Yue;Zhenbo Li;Scott Q. Harper;Robin L. Davisson

  • A hybrid vector system expands adeno-associated viral vector packaging capacity in a transgene-independent manner.

    Arkasubhra Ghosh;Yongping Yue;Yi Lai;Dongsheng Duan

  • Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy.

    Jin-Hong Shin;Jin-Hong Shin;Xiufang Pan;Chady H Hakim;Hsiao T Yang

  • Structural analysis of adeno-associated virus transduction circular intermediates.

    Dongsheng Duan;Ziying Yan;Yongping Yue;John F. Engelhardt

  • Prevention of Dystrophin-Deficient Cardiomyopathy in Twenty-One-Month-Old Carrier Mice by Mosaic Dystrophin Expression or Complementary Dystrophin/Utrophin Expression

    Brian Bostick;Yongping Yue;Chun Long;Dongsheng Duan

  • Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus

    Yongping Yue;Xiufang Pan;Chady H. Hakim;Kasun Kodippili

  • Enhancement of Muscle Gene Delivery with Pseudotyped Adeno-Associated Virus Type 5 Correlates with Myoblast Differentiation

    Dongsheng Duan;Ziying Yan;Yongping Yue;Wei Ding

  • Formation of Adeno-Associated Virus Circular Genomes Is Differentially Regulated by Adenovirus E4 ORF6 and E2a Gene Expression

    Dongsheng Duan;Prerna Sharma;Lorita Dudus;Yulong Zhang

Frequent Co-Authors

Dongsheng Duan
Dongsheng Duan University of Missouri
Jeffrey S. Chamberlain
Jeffrey S. Chamberlain University of Washington
John F. Engelhardt
John F. Engelhardt University of Iowa
Charles A. Gersbach
Charles A. Gersbach Duke University
Peter S. Rabinovitch
Peter S. Rabinovitch University of Washington
Ziying Yan
Ziying Yan University of Iowa
Henk Granzier
Henk Granzier University of Arizona
Wei-Jun Qian
Wei-Jun Qian Pacific Northwest National Laboratory
Roger J. Hajjar
Roger J. Hajjar Icahn School of Medicine at Mount Sinai
Jianming Qiu
Jianming Qiu University of Kansas

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