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Pieter Mestdagh

Pieter Mestdagh

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
22092
World Ranking
5872
National Ranking
97

Overview

Pieter Mestdagh is affiliated with Ghent University in Belgium and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology, Cancer Research, Immunology, Infectious Diseases, and Biomedical Engineering. Their research scope covers several specialized topics including cancer-related molecular mechanisms research, RNA modifications and cancer, RNA research and splicing, microRNA in disease regulation, molecular biology techniques and applications, cancer genomics and diagnostics, and single-cell and spatial transcriptomics.

The scientist has authored multiple papers, contributing to the dissemination of knowledge across influential journals. Recent publications include:

  • Benchmarking of cell type deconvolution pipelines for transcriptomics data (2020, Nature Communications)
  • RNAcentral 2021: secondary structure integration, improved sequence search and new member databases (2020, Nucleic Acids Research)
  • The RNA Atlas expands the catalog of human non-coding RNAs (2021, Nature Biotechnology)
  • A microRNA-21-mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis (2021, Science Translational Medicine)
  • Charting Extracellular Transcriptomes in The Human Biofluid RNA Atlas (2020, Cell Reports)

Pieter Mestdagh frequently collaborates with a consistent group of co-authors, including Jo Vandesompele, Jasper Anckaert, Justine Nuytens, Nurten Yigit, and Annelien Morlion. These collaborations reflect a sustained network contributing to various strands of molecular biology and cancer research.

The scientist's work is regularly published in prominent scientific venues. The most frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Clinical Cancer Research, Journal of Extracellular Vesicles, and Scientific Reports.

This profile demonstrates Pieter Mestdagh's focus on fundamental and applied research areas within molecular biology and cancer research, particularly with respect to RNA biology and transcriptomics techniques. The breadth of topics and venues reflects a multidisciplinary approach to understanding molecular mechanisms in health and disease.

Best Publications

  • miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

    Li Ma;Jennifer Young;Harsha Prabhala;Elizabeth Pan

  • A novel and universal method for microRNA RT-qPCR data normalization

    Pieter Mestdagh;Pieter Van Vlierberghe;An-Sofie De Weer;Daniel Muth

  • EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

    Jan Van Deun;Pieter Mestdagh;Patrizia Agostinis;Özden Akay

  • The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

    Jan Van Deun;Pieter Mestdagh;Raija Sormunen;Veronique Cocquyt

  • Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

    Pieter Mestdagh;Nicole Hartmann;Lukas Baeriswyl;Ditte Andreasen

  • LNCipedia: a database for annotated human lncRNA transcript sequences and structures.

    Pieter-Jan Volders;Kenny Helsens;Xiaowei Wang;Björn Menten

  • A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

    Ashton C Berger;Anil Korkut;Rupa S Kanchi;Apurva M Hegde

  • LNCipedia 5: towards a reference set of human long non-coding RNAs.

    Pieter-Jan Volders;Jasper Anckaert;Kenneth Verheggen;Justine Nuytens

  • Melanoma addiction to the long non-coding RNA SAMMSON.

    Eleonora Leucci;Roberto Vendramin;Marco Spinazzi;Patrick Laurette

  • LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

    Jan J Molenaar;Raquel Domingo-Fernández;Marli E Ebus;Sven Lindner

  • An update on LNCipedia: a database for annotated human lncRNA sequences

    Pieter-Jan Volders;Kenneth Verheggen;Gerben Menschaert;Klaas Vandepoele

  • High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA

    Pieter Mestdagh;Tom Feys;Nathalie Bernard;Simone Guenther

  • The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma

    Pieter Mestdagh;Anna-Karin Bostrom;Francis Impens;Erik Fredlund;Erik Fredlund

  • Benchmarking of RNA-sequencing analysis workflows using whole-transcriptome RT-qPCR expression data

    Celine Everaert;Manuel Luypaert;Jesper L. V. Maag;Quek Xiu Cheng

  • Benchmarking of cell type deconvolution pipelines for transcriptomics data.

    Francisco Avila Cobos;Francisco Avila Cobos;José Alquicira-Hernandez;José Alquicira-Hernandez;Joseph E. Powell;Joseph E. Powell;Pieter Mestdagh

  • RNAcentral: a comprehensive database of non-coding RNA sequences.

    Anton I. Petrov;Simon J E Kay;Ioanna Kalvari;Kevin L. Howe

  • MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer.

    Kah Hoong Chang;Pieter Mestdagh;Jo Vandesompele;Michael J Kerin

  • MicroRNA Expression in Induced Sputum of Smokers and Patients with Chronic Obstructive Pulmonary Disease

    Geert R Van Pottelberge;Pieter Mestdagh;Ken R Bracke;Olivier Thas

  • LNCipedia: a database for annotated human lncRNA transcript sequences and structures

    Pieter-Jan Volders;Kenny Helsens;Xiaowei Wang;Lennart Martens

  • High-throughput stem-loop RT-PCR miRNA expression profiling using minute amounts of input RNA

    Pieter Mestdagh;Tom Feys;Nathalie Bernard;Simone Guenther

Frequent Co-Authors

Jo Vandesompele
Jo Vandesompele Ghent University
Katleen De Preter
Katleen De Preter Ghent University
Franki Speleman
Franki Speleman Ghent University
Johannes H. Schulte
Johannes H. Schulte Charité - University Medicine Berlin
Ken R. Bracke
Ken R. Bracke Ghent University Hospital
Nadine Van Roy
Nadine Van Roy Ghent University
Guy Brusselle
Guy Brusselle Ghent University Hospital
Olivier De Wever
Olivier De Wever Ghent University
Bruce Poppe
Bruce Poppe Ghent University Hospital
Tom Taghon
Tom Taghon Ghent University

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