James E. K. Hildreth

Research.com Recognitions

• 2011 - National Institutes of Health Director's Pioneer Award
• 2008 - Member of the National Academy of Medicine (NAM)

Overview

Best Publications

• Evidence for Budding of Human Immunodeficiency Virus Type 1 Selectively from Glycolipid-Enriched Membrane Lipid Rafts

  Dzung H. Nguyen;James E. K. Hildreth

  1166
  Citations

• The Trojan exosome hypothesis.

  Stephen J. Gould;Amy M. Booth;James E. K. Hildreth

  842
  Citations

• Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane

  Amy M. Booth;Yi Fang;Jonathan K. Fallon;Jr-Ming Yang

  682
  Citations

• Lipid rafts and HIV pathogenesis: host membrane cholesterol is required for infection by HIV type 1.

  Zhaohao Liao;Lisa M. Cimakasky;Richard Hampton;Dzung H. Nguyen

  506
  Citations

• A human lymphocyte‐associated antigen involved in cell‐mediated lympholysis

  James E. K. Hildreth;Frances M. Gotch;Phyllis D. K. Hildreth;Andrew J. McMichael

  463
  Citations

• Evidence that HIV budding in primary macrophages occurs through the exosome release pathway.

  Deborah Greene Nguyen;Amy Booth;Stephen J. Gould;James E.K. Hildreth

  461
  Citations

• Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation.

  James E. K. Hildreth;Rimas J. Orentas

  356
  Citations

• Involvement of macrophage mannose receptor in the binding and transmission of HIV by macrophages.

  Deborah Greene Nguyen;James E K Hildreth

  352
  Citations

• Actin-Dependent Receptor Colocalization Required for Human Immunodeficiency Virus Entry into Host Cells

  Sujatha Iyengar;James E. K. Hildreth;David H. Schwartz

  290
  Citations

• Cholesterol Depletion of Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus with β-Cyclodextrin Inactivates and Permeabilizes the Virions: Evidence for Virion-Associated Lipid Rafts

  David R. M. Graham;Elena Chertova;Joanne M. Hilburn;Larry O. Arthur

  280
  Citations

• N-D-Gluco-N-methylalkanamide compounds, a new class of non-ionic detergents for membrane biochemistry.

  James E. K. Hildreth

  253
  Citations

• The primary structure of the beta-subunit of the cell surface adhesion glycoproteins LFA-1, CR3 and p150,95 and its relationship to the fibronectin receptor.

  S. K. A. Law;J. Gagnon;J. E. K. Hildreth;C. E. Wells

  253
  Citations

• Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV

  Rimas J. Orentas;James E. K. Hildreth

  249
  Citations

• Lipid rafts and HIV pathogenesis: virion-associated cholesterol is required for fusion and infection of susceptible cells.

  Zhaohao Liao;David R. Graham;James E.K. Hildreth

  238
  Citations

• Purification and characterization of human lysosomal membrane glycoproteins.

  Shrikant M. Mane;Louis Marzella;Dorothy F. Bainton;Valerie K. Holt

  232
  Citations

• The human lymphocyte function-associated (HLFA) antigen and a related macrophage differentiation antigen (HMac-1): functional effects of subunit-specific monoclonal antibodies.

  J. E. K. Hildreth;J. T. August

  218
  Citations

• Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation.

  Guochun Jiang;Erica A. Mendes;Philipp Kaiser;Philipp Kaiser;Daniel P. Wong;Daniel P. Wong

  210
  Citations

• Monoclonal antibodies to Epstein-Barr virus-induced, transformation-associated cell surface antigens: binding patterns and effect upon virus-specific T-cell cytotoxicity.

  M. Rowe;J. E K Hildreth;A. B. Rickinson;M. A. Epstein

  208
  Citations

• Induction of CD4+ human cytolytic T cells specific for HIV-infected cells by a gp160 subunit vaccine

  Rimas J. Orentas;James E K Hildreth;Eugene Obah;Michael J Polydefkis

  191
  Citations

• Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells

  Atanu K. Khatua;Harry E. Taylor;James E. K. Hildreth;Waldemar Popik

  187
  Citations

• Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent

  Kristen V. Khanna;Kevin J. Whaley;Larry Zeitlin;Thomas R. Moench

  182
  Citations

• Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS.

  Nia D. Banks;Nicole Kinsey;Janice Clements;James E. K. Hildreth

  174
  Citations