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Immunology

D-Index
58
Citations
11049
World Ranking
3541
National Ranking
52

Overview

Ken R. Bracke is a researcher affiliated with Ghent University Hospital in Belgium, focusing on biomedical sciences within the fields of medicine and biochemistry, genetics, and molecular biology. Their scholarly work spans multiple specialized areas including molecular biology, pulmonary and respiratory medicine, infectious diseases, immunology, and cancer research.

The scientist's research topics cover a range of key areas, notably:

  • Cancer-related molecular mechanisms research
  • SARS-CoV-2 and COVID-19 research
  • COVID-19 clinical research studies
  • RNA modifications and cancer
  • Neonatal respiratory health research
  • Chronic obstructive pulmonary disease (COPD) research
  • MicroRNA in disease regulation

Ken R. Bracke has contributed to peer-reviewed literature with papers published in well-recognized venues. Some recent examples include:

  • "Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease," 2021, American Journal of Respiratory and Critical Care Medicine
  • "The RNA Atlas expands the catalog of human non-coding RNAs," 2021, Nature Biotechnology
  • "A microRNA-21-mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis," 2021, Science Translational Medicine
  • "The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD," 2022, Nature Communications
  • "Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects," 2020, European Respiratory Journal

Publication frequency indicates a consistent presence in the following venues:

  • American Journal of Respiratory and Critical Care Medicine
  • European Respiratory Journal
  • Nature Communications
  • Nature Biotechnology
  • ERJ Open Research

The scientist frequently collaborates with colleagues including:

  • Guy Brusselle
  • Tania Maes
  • Hannelore P. Van Eeckhoutte
  • Philip M. Hansbro
  • Pieter Mestdagh

The combination of expertise in molecular biology and pulmonary medicine underpins the scientist's substantial work on respiratory diseases, particularly chronic obstructive pulmonary disease and COVID-19 related clinical and molecular research. This interdisciplinary approach bridges disease pathology with molecular regulatory mechanisms, such as the role of microRNAs and inflammatory signaling pathways.

Best Publications

  • New insights into the immunology of chronic obstructive pulmonary disease

    Guy G Brusselle;Guy F Joos;Ken R Bracke

  • Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema

    Ingel K Demedts;Tine Demoor;Ken R Bracke;Guy F Joos

  • Eosinophils in the spotlight: Eosinophilic airway inflammation in nonallergic asthma.

    Guy G Brusselle;Tania Maes;Ken R Bracke

  • Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease.

    Ingel K. Demedts;Ken R. Bracke;Geert Van Pottelberge;Dries Testelmans

  • Cigarette Smoke-Induced Pulmonary Inflammation and Emphysema Are Attenuated in CCR6-Deficient Mice

    Ken R. Bracke;An I. D’hulst;Tania Maes;Katrien B. Moerloose

  • Role of IL-1α and the Nlrp3/caspase-1/IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD

    N S Pauwels;K R Bracke;L L Dupont;G R Van Pottelberge

  • MicroRNA Expression in Induced Sputum of Smokers and Patients with Chronic Obstructive Pulmonary Disease

    Geert R Van Pottelberge;Pieter Mestdagh;Ken R Bracke;Olivier Thas

  • Matrix metalloproteinases in asthma and COPD

    Ingel K Demedts;Guy G Brusselle;Ken R Bracke;Karim Y Vermaelen

  • Activation of the WNT/β-catenin pathway attenuates experimental emphysema.

    Nikolaus Kneidinger;Ali Önder Yildirim;Jens Callegari;Shinji Takenaka

  • Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung.

    Katrien C. De Grove;Sharen Provoost;Fien M. Verhamme;Ken R. Bracke

  • Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut.

    Liesbeth Allais;Frederiek-Maarten Kerckhof;Stephanie Verschuere;Ken R. Bracke

  • Asthma inflammatory phenotypes show differential microRNA expression in sputum

    Tania Maes;Francisco Avila Cobos;Florence Schleich;Valentina Sorbello

  • Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Daan W. Loth;María Soler Artigas;Sina A. Gharib;Louise V. Wain

  • Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease.

    Zhe Lu;Hannelore P Van Eeckhoutte;Gang Liu;Gang Liu;Prema M Nair

  • Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD.

    Hoeke A Baarsma;Wioletta Skronska-Wasek;Kathrin Mutze;Florian Ciolek

  • Lymphoid follicles in (very) severe COPD: beneficial or harmful?

    Guy Brusselle;Tine Demoor;Ken Bracke;C.-A. Brandsma

  • Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis

    Elena B Lugli;Raquel E S M Correia;Roman Fischer;Karin Lundberg

  • Different roles for human lung dendritic cell subsets in pulmonary immune defense mechanisms.

    Ingel K. Demedts;Ken R. Bracke;Tania Maes;Guy F. Joos

  • Enhanced pulmonary leptin expression in patients with severe COPD and asymptomatic smokers

    J H J Vernooy;N E A Drummen;R J van Suylen;R H E Cloots

  • Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?

    An I D'hulst;Tania Maes;Ken R Bracke;Ingel K Demedts

  • Chronic Obstructive Pulmonary Disease 1 New insights into the immunology of chronic obstructive pulmonary disease

    G G Brusselle;G F Joos;K R Bracke;Guy G Brusselle

Frequent Co-Authors

Guy Brusselle
Guy Brusselle Ghent University Hospital
Guy Joos
Guy Joos Ghent University Hospital
Guy Joos
Guy Joos Ghent University Hospital
Pieter Mestdagh
Pieter Mestdagh Ghent University
Emiel F.M. Wouters
Emiel F.M. Wouters Maastricht University
Jo Vandesompele
Jo Vandesompele Ghent University
Bart N. Lambrecht
Bart N. Lambrecht Ghent University
Peter Vandenabeele
Peter Vandenabeele Ghent University
Josée Dupuis
Josée Dupuis McGill University
Pieter S. Hiemstra
Pieter S. Hiemstra Leiden University Medical Center

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