World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
155
Citations
74803
World Ranking
977
National Ranking
561

Research.com Recognitions

  • 2003 - Member of the National Academy of Medicine (NAM)
  • 1988 - E. Mead Johnson Award, Society for Pediatric Research
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Jeffrey A. Whitsett is affiliated with Cincinnati Children's Hospital Medical Center in the United States. Their research spans primarily across the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with particular focus on Molecular Biology and Pulmonary and Respiratory Medicine.

The scientist's work engages extensively with subfields such as Surgery, Epidemiology, and Cancer Research. Key topics covered include Neonatal Respiratory Health Research, Congenital Diaphragmatic Hernia Studies, Renal and related cancers, Single-cell and spatial transcriptomics, Respiratory viral infections research, Congenital heart defects research, and Tissue Engineering and Regenerative Medicine.

Jeffrey A. Whitsett has contributed to numerous publications, often in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Respiratory Cell and Molecular Biology
  • American Journal of Respiratory and Critical Care Medicine
  • Nature Communications
  • iScience

Notable recent papers include:

  • "An integrated cell atlas of the lung in health and disease," 2023, Nature Medicine
  • "Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19," 2020, Immunity
  • "The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future," 2020, Cell Stem Cell
  • "Guided construction of single cell reference for human and mouse lung," 2023, Nature Communications
  • "Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell," 2020, American Journal of Respiratory and Critical Care Medicine

Frequent collaborators in their publications include:

  • Minzhe Guo
  • Yan Xu
  • Joseph A. Kitzmiller
  • William J. Zacharias
  • Vladimir V. Kalinichenko

Jeffrey A. Whitsett has been recognized with several awards, including membership in the National Academy of Medicine since 2003, the E. Mead Johnson Award from the Society for Pediatric Research in 1988, and membership in the Association of American Physicians.

Best Publications

  • Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis

    Glenn Dranoff;Alexander D. Crawford;Michel Sadelain;Beverly Ream

  • A Mutation in the Surfactant Protein C Gene Associated with Familial Interstitial Lung Disease

    Lawrence M. Nogee;Alston E. Dunbar;Susan E. Wert;Frederic Askin

  • Pulmonary Alveolar Proteinosis

    Bruce C. Trapnell;Jeffrey A. Whitsett;Koh Nakata

  • ABCA3 gene mutations in newborns with fatal surfactant deficiency.

    Sergey Shulenin;Lawrence M. Nogee;Tarmo Annilo;Susan E. Wert

  • GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1.

    Yoko Shibata;Pierre Yves Berclaz;Zissis C. Chroneos;Mitsuhiro Yoshida

  • Hydrophobic surfactant proteins in lung function and disease.

    Jeffrey A Whitsett;Timothy E Weaver

  • Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung.

    K. Peters;S. Werner;Xiang Liao;S. Wert

  • Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice.

    Susan E. Wert;Mitsuhiro Yoshida;Ann Marie LeVine;Machiko Ikegami

  • Serial Changes in Surfactant-associated Proteins in Lung and Serum before and after Onset of ARDS

    Kelly E. Greene;Jo Rae Wright;Kenneth P. Steinberg;John T. Ruzinski

  • Early restriction of peripheral and proximal cell lineages during formation of the lung.

    Anne Karina T. Perl;Susan E. Wert;Andras Nagy;Corrinne G. Lobe

  • Alveolar Surfactant Homeostasis and the Pathogenesis of Pulmonary Disease

    Jeffrey A. Whitsett;Susan E. Wert;Timothy E. Weaver

  • Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis

    Yoshitaka Miyazaki;Kimi Araki;Christian Vesin;Irene Garcia

  • Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.

    Anjali Jacob;Anjali Jacob;Michael Morley;Finn Hawkins;Finn Hawkins;Katherine B. McCauley;Katherine B. McCauley

  • Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice

    Kathryn A. Wikenheiser;Diane K. Vorbroker;Ward R. Rice;Jean C. Clark

  • β-Catenin Is Required for Specification of Proximal/Distal Cell Fate during Lung Morphogenesis

    Michael L. Mucenski;Susan E. Wert;Jennifer M. Nation;David E. Loudy

  • SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

    Gang Chen;Thomas R. Korfhagen;Yan Xu;Joseph Kitzmiller

  • Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway.

    Christopher L. Karp;Leah M. Flick;Kiwon W. Park;Samir Softic

  • Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense.

    Bruce C Trapnell;Jeffrey A Whitsett

  • ABCA3 mutations associated with pediatric interstitial lung disease.

    Janine E. Bullard;Susan E. Wert;Jeffrey A. Whitsett;Michael Dean

  • Altered stability of pulmonary surfactant in SP-C-deficient mice

    Stephan W. Glasser;Michael S. Burhans;Thomas R. Korfhagen;Cheng Lun Na

Frequent Co-Authors

Susan E. Wert
Susan E. Wert Cincinnati Children's Hospital Medical Center
Yan Xu
Yan Xu Cincinnati Children's Hospital Medical Center
Machiko Ikegami
Machiko Ikegami University of Cincinnati
Alan H. Jobe
Alan H. Jobe Cincinnati Children's Hospital Medical Center
Thomas R. Korfhagen
Thomas R. Korfhagen Cincinnati Children's Hospital Medical Center
S. Steven Potter
S. Steven Potter Cincinnati Children's Hospital Medical Center
Garry R. Cutting
Garry R. Cutting Johns Hopkins University School of Medicine
Robyn J. Barst
Robyn J. Barst Columbia University
Leah Rae Donahue
Leah Rae Donahue The Jackson Laboratory
Michael Dean
Michael Dean National Institutes of Health

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