What is he best known for?
The fields of study he is best known for:
Donald G. Payan mainly investigates Cell biology, Molecular biology, Immunology, Receptor and Inflammation.
His Cell biology research is multidisciplinary, incorporating elements of Free nerve ending, Biochemistry, Peptide and Histamine.
His Molecular biology study combines topics in areas such as Gene expression, Substance P, Endocytosis, Protein kinase domain and Endosome.
His Immunology research includes elements of Fostamatinib, Syk and AXL receptor tyrosine kinase.
His study in Receptor is interdisciplinary in nature, drawing from both Endocrinology, Antibody, Transfection and Trypsin.
His Inflammation study deals with Arthritis intersecting with Asthma, Inflammatory bowel disease and Pathogenesis.
His most cited work include:
- Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2 (422 citations)
- R406, an Orally Available Spleen Tyrosine Kinase Inhibitor Blocks Fc Receptor Signaling and Reduces Immune Complex-Mediated Inflammation (408 citations)
- R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer (355 citations)
What are the main themes of his work throughout his whole career to date?
Donald G. Payan mainly focuses on Biochemistry, Cell biology, Molecular biology, Receptor and Internal medicine.
He interconnects Epitope and Immunoglobulin E in the investigation of issues within Biochemistry.
His Cell biology research is multidisciplinary, incorporating perspectives in Neuropeptide, Cell, Internalization and Mast cell.
Donald G. Payan has included themes like Cell culture, Transfection, Gene expression, Peptide sequence and Intracellular in his Molecular biology study.
Donald G. Payan combines subjects such as Antibody and Lymphoblast with his study of Receptor.
In his study, Immunology is inextricably linked to Endocrinology, which falls within the broad field of Internal medicine.
He most often published in these fields:
- Biochemistry (25.42%)
- Cell biology (25.00%)
- Molecular biology (24.58%)
What were the highlights of his more recent work (between 2007-2019)?
- Stereochemistry (6.67%)
- Internal medicine (20.83%)
- Cancer research (7.08%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Stereochemistry, Internal medicine, Cancer research, Immunology and Kinase.
His Internal medicine course of study focuses on Endocrinology and T cell.
His research integrates issues of Degranulation and Syk in his study of Immunology.
His study looks at the relationship between Degranulation and topics such as Salt, which overlap with Biochemistry.
His Kinase research includes themes of Cell, Cell culture, In vivo and Transcription factor.
His Cell research incorporates themes from Muscle tissue, Molecular biology and Signal transduction, Receptor signaling.
Between 2007 and 2019, his most popular works were:
- R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer (355 citations)
- An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus. (157 citations)
- JAK3 Inhibition Significantly Attenuates Psoriasiform Skin Inflammation in CD18 Mutant PL/J Mice (80 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Internal medicine, Cancer research, Endocrinology, Immunology and Pharmacology.
His work deals with themes such as AMP-activated protein kinase and AMPK, which intersect with Internal medicine.
His studies in Cancer research integrate themes in fields like Hematology, Cancer and Kinase.
Donald G. Payan works in the field of Endocrinology, focusing on Nitric oxide in particular.
His Immunology study combines topics in areas such as Metastasis and Syk.
His T cell research is multidisciplinary, incorporating perspectives in Inflammation, Receptor, Lesion and Psoriasis.
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