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Jan-Willem de Gier

Jan-Willem de Gier

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10242
World Ranking
15118
National Ranking
228

Overview

Jan-Willem de Gier is affiliated with Stockholm University in Sweden. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a notable focus on molecular biology and epidemiology.

The scientist's work covers several key research topics, including:

  • RNA and protein synthesis mechanisms
  • Bacterial Genetics and Biotechnology
  • Influenza Virus Research Studies
  • Bacteriophages and microbial interactions
  • Monoclonal and Polyclonal Antibodies Research
  • Respiratory viral infections research
  • Escherichia coli research studies

Jan-Willem de Gier has published in a variety of academic venues, with frequent contributions to:

  • Frontiers in Bioengineering and Biotechnology
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Journal of Virology

Recent publications include:

  • A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds, 2020, Nature
  • Strategies to Enhance Periplasmic Recombinant Protein Production Yields in Escherichia coli, 2021, Frontiers in Bioengineering and Biotechnology
  • N-Linked Glycan Sites on the Influenza A Virus Neuraminidase Head Domain Are Required for Efficient Viral Incorporation and Replication, 2020, Journal of Virology
  • Influenza virus and pneumococcal neuraminidases enhance catalysis by similar yet distinct sialic acid-binding strategies, 2023, Journal of Biological Chemistry
  • Cotranslational folding of alkaline phosphatase in the periplasm of Escherichia coli, 2020, Protein Science

The scientist has collaborated regularly with several coauthors, including:

  • Alexandros Karyolaimos
  • Robert Daniels
  • Rageia Elfageih
  • Jin Gao
  • Henrik Østbye

Best Publications

  • Tuning Escherichia coli for membrane protein overexpression

    Samuel Wagner;Mirjam M. Klepsch;Susan Schlegel;Ansgar Appel

  • YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase

    Pier A. Scotti;Malene L. Urbanus;Josef Brunner;Jan‐Willem L. de Gier

  • Consequences of Membrane Protein Overexpression in Escherichia coli

    Samuel Wagner;Louise Baars;A. Jimmy Ytterberg;Anja Klussmeier

  • Optimization of membrane protein overexpression and purification using GFP fusions

    David Drew;Mirjam Lerch;Edmund Kunji;Dirk-Jan Slotboom

  • The Escherichia coli SRP and SecB targeting pathways converge at the translocon

    Quido A. Valent;Pier A. Scotti;Stephen High;Jan Willem L De Gier

  • Biogenesis of inner membrane proteins in Escherichia coli.

    Joen Luirink;Gunnar von Heijne;Edith Houben;Jan-Willem de Gier

  • Competition between Sec- and TAT-dependent protein translocation in Escherichia coli.

    S. Cristóbal;J.-W. de Gier;Henrik Nielsen;G. von Heijne

  • Rationalizing membrane protein overexpression

    Samuel Wagner;Mirjam Lerch Bader;David Drew;Jan-Willem de Gier

  • Green fluorescent protein as an indicator to monitor membrane protein overexpression in Escherichia coli.

    David E Drew;Gunnar von Heijne;Pär Nordlund;Jan-Willem L de Gier

  • Sec-dependent membrane protein insertion: sequential interaction of nascent FtsQ with SecY and YidC.

    Malene L Urbanus;Pier A Scotti;Linda Fröderberg;Annika Sääf

  • Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.

    David Drew;Dan Sjöstrand;Johan Nilsson;Thomas Urbig

  • Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor.

    Quido A. Valent;Jan‐Willem L. De Gier;Gunnar von Heijne;Debra A. Kendall

  • Assembly of a cytoplasmic membrane protein in Escherichia coli is dependent on the signal recognition particle

    Jan-Willem L. de Gier;Parvaneh Mansournia;Quido A. Valent;Gregory J. Phillips

  • Function of YidC for the Insertion of M13 Procoat Protein inEscherichia coli TRANSLOCATION OF MUTANTS THAT SHOW DIFFERENCES IN THEIR MEMBRANE POTENTIAL DEPENDENCE AND Sec REQUIREMENT

    James C. Samuelson;Fenglei Jiang;Liang Yi;Minyong Chen

  • YidC/Oxa1p/Alb3: evolutionarily conserved mediators of membrane protein assembly.

    Joen Luirink;Tore Samuelsson;Jan-Willem de Gier

  • Assembly and overexpression of membrane proteins in Escherichia coli.

    David Drew;Linda Fröderberg;Louise Baars;Jan-Willem L de Gier

  • A scalable, GFP-based pipeline for membrane protein overexpression screening and purification

    David Drew;Dirk-Jan Slotboom;Giulia Friso;Torsten Reda

  • Optimizing Membrane Protein Overexpression in the Escherichia coli strain Lemo21(DE3)

    Susan Schlegel;John Lofblom;Chiara Lee;Anna Hjelm

  • Optimizing heterologous protein production in the periplasm of E. coli by regulating gene expression levels

    Susan Schlegel;Edurne Rujas;Anders Jimmy Ytterberg;Roman A Zubarev

  • Consequences of membrane protein overexpression in Escherichia coli

    Samuel Wagner;Louise Baars;A. Jimmy Ytterberg;Anja Klußmeier

Frequent Co-Authors

Joen Luirink
Joen Luirink Vrije Universiteit Amsterdam
Gunnar von Heijne
Gunnar von Heijne Stockholm University
Klaas J. van Wijk
Klaas J. van Wijk Cornell University
Bauke Oudega
Bauke Oudega Vrije Universiteit Amsterdam
Dirk Jan Slotboom
Dirk Jan Slotboom University of Groningen
Adriaan H. Stouthamer
Adriaan H. Stouthamer Vrije Universiteit Amsterdam
Ross E. Dalbey
Ross E. Dalbey The Ohio State University
John van der Oost
John van der Oost Wageningen University & Research
Andreas Kuhn
Andreas Kuhn University of Hohenheim
Josef Brunner
Josef Brunner ETH Zurich

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