What is he best known for?
The fields of study he is best known for:
William M. Pierce focuses on Oxidative stress, Biochemistry, Alzheimer's disease, Proteomics and Protein oxidation.
He is investigating Endocrinology and Internal medicine as part of his examination of Oxidative stress.
The various areas that William M. Pierce examines in his Endocrinology study include TFAM, Mitochondrial DNA and Oxidative phosphorylation.
Much of his study explores Biochemistry relationship to Neurodegeneration.
As a part of the same scientific family, William M. Pierce mostly works in the field of Alzheimer's disease, focusing on Amyloid and, on occasion, Tau protein and Amyloid precursor protein.
His study looks at the relationship between Proteomics and topics such as Pathogenesis, which overlap with 4-Hydroxynonenal, Huntingtin, Aconitase, Mutation and Genetically modified mouse.
His most cited work include:
- Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, α-enolase and heat shock cognate 71 (528 citations)
- Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. (516 citations)
- Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer's disease (298 citations)
What are the main themes of his work throughout his whole career to date?
Biochemistry, Molecular biology, Oxidative stress, Internal medicine and Endocrinology are his primary areas of study.
His work in Proteomics, DNA adduct, Enzyme, Phosphorylation and Protein kinase A is related to Biochemistry.
His work carried out in the field of Molecular biology brings together such families of science as Heat shock protein, Receptor and Western blot.
His Oxidative stress study combines topics in areas such as Alzheimer's disease, Oxidative phosphorylation and Neurodegeneration.
William M. Pierce has researched Alzheimer's disease in several fields, including Dementia and Pathogenesis.
His biological study spans a wide range of topics, including Microsome and Hydroxylation.
He most often published in these fields:
- Biochemistry (42.25%)
- Molecular biology (23.94%)
- Oxidative stress (21.83%)
What were the highlights of his more recent work (between 2009-2020)?
- Biochemistry (42.25%)
- Proteomics (21.83%)
- Alzheimer's disease (14.79%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Biochemistry, Proteomics, Alzheimer's disease, Oxidative stress and Endocrinology.
His work often combines Biochemistry and Wheat germ agglutinin studies.
His Proteomics research incorporates themes from Proteome, Protein disulfide-isomerase, Immunology, Blood proteins and Dementia.
His Alzheimer's disease research is multidisciplinary, incorporating elements of Molecular biology, Gene knockin and Neurodegeneration.
His Oxidative stress research is multidisciplinary, incorporating perspectives in Reactive oxygen species, Amyloid beta, Pharmacology and In vivo.
His Endocrinology research includes elements of Fructose, Nonalcoholic fatty liver disease, Fatty liver and Internal medicine.
Between 2009 and 2020, his most popular works were:
- Redox proteomic analysis of carbonylated brain proteins in Mild cognitive impairment and early alzheimer's disease (97 citations)
- Alterations in brain antioxidant enzymes and redox proteomic identification of oxidized brain proteins induced by the anti-cancer drug adriamycin: implications for oxidative stress-mediated chemobrain. (93 citations)
- 2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: implications for the reactive oxygen species-mediated mechanisms of chemobrain. (87 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Alzheimer's disease, Oxidative stress, Proteomics, Biochemistry and Internal medicine.
His Alzheimer's disease study combines topics from a wide range of disciplines, such as Blood proteins, Molecular biology and Neurodegeneration.
His work deals with themes such as Hsp70, Protein kinase A and Protein oxidation, which intersect with Neurodegeneration.
His Oxidative stress research is multidisciplinary, relying on both Proteome, Protein subunit, Immunoprecipitation and Amyloid precursor protein.
His work on Biochemistry is being expanded to include thematically relevant topics such as Pharmacology.
His study focuses on the intersection of Internal medicine and fields such as Endocrinology with connections in the field of Copper deficiency and Fructose.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
