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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
7711
World Ranking
16372
National Ranking
1293

Overview

J. Michael Edwardson is affiliated with the University of Cambridge in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, encompassing three main subfields: molecular biology, genetics, and biochemistry. Additional areas of study include cell biology and oncology.

The scientist's work extensively covers topics such as RNA and protein synthesis mechanisms, lipid metabolism and biosynthesis, endoplasmic reticulum stress and disease, peroxisome proliferator-activated receptors, DNA repair mechanisms, bacterial genetics and biotechnology, and lipid membrane structure and behavior.

Notable recent publications by Edwardson include:

  • "Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation," 2020, Scientific Reports
  • "Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy," 2020, Proceedings of the National Academy of Sciences
  • "Syncollin is an antibacterial polypeptide," 2021, Cellular Microbiology
  • "Activation of P2X4 receptors induces an increase in the area of the extracellular region and a decrease in receptor mobility," 2020, FEBS Letters
  • "Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation," 2020, Apollo (University of Cambridge)

The scientist has frequently collaborated with several researchers, including:

  • M. F. Michelle Sim
  • Elisa Persiani
  • Mesbah Talukder
  • George D. Mcilroy
  • Ahlima Roumane

Edwardson's work has been published in various scientific venues. The most frequent publication platforms are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Proceedings of the National Academy of Sciences
  • Cellular Microbiology
  • FEBS Letters

Best Publications

  • Endocytosis and recycling of G protein-coupled receptors

    Jennifer A Koenig;J.Michael Edwardson

  • Real-time analysis of the effects of cholesterol on lipid raft behavior using atomic force microscopy.

    Jared C. Lawrence;David E. Saslowsky;J. Michael Edwardson;Robert M. Henderson

  • A novel function for the second C2 domain of synaptotagmin. Ca2+-triggered dimerization.

    Edwin R. Chapman;Seong An;J. Michael Edwardson;Reinhard Jahn

  • Atomic force microscopy imaging demonstrates that P2X2 receptors are trimers but that P2X6 receptor subunits do not oligomerize.

    Nelson P. Barrera;Susan J. Ormond;Robert M. Henderson;Ruth D. Murrell-Lagnado

  • Structure of Ocr from bacteriophage T7, a protein that mimics B-form DNA.

    Malcolm Walkinshaw;Paul Taylor;S S Sturrock;C Atanasiu

  • Placental Alkaline Phosphatase Is Efficiently Targeted to Rafts in Supported Lipid Bilayers

    David E. Saslowsky;Jared Lawrence;Xiaoyan Ren;Deborah A. Brown

  • Compound exocytosis: mechanisms and functional significance.

    James A. Pickett;J. Michael Edwardson

  • Fast-scan atomic force microscopy reveals that the type III restriction enzyme EcoP15I is capable of DNA translocation and looping

    Neal Crampton;Masatoshi Yokokawa;David T. F. Dryden;J. Michael Edwardson

  • Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells

    Miyyada Boumechache;Marianela Masin;J. Michael Edwardson;Dariusz C. Górecki

  • Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT3 receptors

    Nelson P. Barrera;Paul Herbert;Robert M. Henderson;Ian L. Martin

  • Direct evidence for functional TRPV1/TRPA1 heteromers

    Michael J. M. Fischer;Michael J. M. Fischer;Dilshan Balasuriya;Pia Jeggle;Tom A. Goetze;Tom A. Goetze

  • Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells

    Ward C. Tucker;J. Michael Edwardson;Jihong Bai;Hyun-Jung Kim

  • Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion

    Li Ma;Vytautas P. Bindokas;Andrey Kuznetsov;Christopher Rhodes

  • A cell-free system for regulated exocytosis in PC12 cells.

    Julia Avery;Darren J. Ellis;Thorsten Lang;Phillip Holroyd

  • The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement.

    Toshiro Kobori;Graham D. Smith;Richard Sandford;J.Michael Edwardson

  • The Secretory Granule Protein Syncollin Binds to Syntaxin in a Ca2+-Sensitive Manner

    J.Michael Edwardson;Seong An;Reinhard Jahn

  • Association of the endosomal sorting complex ESCRT-II with the Vps20 subunit of ESCRT-III generates a curvature-sensitive complex capable of nucleating ESCRT-III filaments.

    Ian Fyfe;Amber L. Schuh;J. Michael Edwardson;Anjon Audhya

  • Direct visualization of ligand-protein interactions using atomic force microscopy

    Calum S Neish;Ian L Martin;Robert M Henderson;J Michael Edwardson

  • Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer.

    Andrew P. Stewart;Graham D. Smith;Richard N. Sandford;J. Michael Edwardson

  • ESCRT-0 assembles as a heterotetrameric complex on membranes and binds multiple ubiquitinylated cargoes simultaneously.

    Jonathan R. Mayers;Ian Fyfe;Amber L. Schuh;Edwin R. Chapman

Frequent Co-Authors

Edwin R. Chapman
Edwin R. Chapman University of Wisconsin–Madison
David T. F. Dryden
David T. F. Dryden Durham University
Kunio Takeyasu
Kunio Takeyasu Kyoto University
Anjon Audhya
Anjon Audhya University of Wisconsin–Madison
Pierre Paoletti
Pierre Paoletti École Normale Supérieure
Reinhard Jahn
Reinhard Jahn Max Planck Society
A. Jennifer Morton
A. Jennifer Morton University of Cambridge
Lei Wang
Lei Wang University of California, San Francisco
Carl E. Creutz
Carl E. Creutz University of Virginia
Meyer B. Jackson
Meyer B. Jackson University of Wisconsin–Madison

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