World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
81
Citations
23055
World Ranking
3256
National Ranking
1073

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Lyle Isaacs is affiliated with the University of Maryland, College Park in the United States and has contributed extensively to research in the fields of Chemistry and Materials Science. Their scholarly work encompasses diverse subfields such as Organic Chemistry, Materials Chemistry, Spectroscopy, Physical and Theoretical Chemistry, and Cellular and Molecular Neuroscience.

The scientist's research topics include:

  • Supramolecular Chemistry and Complexes
  • Molecular Sensors and Ion Detection
  • Crystallography and molecular interactions
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Luminescence and Fluorescent Materials
  • Metal-Organic Frameworks: Synthesis and Applications

Lyle Isaacs has published in several prominent venues, with frequent contributions to:

  • The Cambridge Structural Database
  • Chemistry - A European Journal
  • Supramolecular Chemistry
  • Angewandte Chemie International Edition
  • Angewandte Chemie

Among recent publications are:

  • "Supramolecular hosts as in vivo sequestration agents for pharmaceuticals and toxins" (2020), published in Chemical Society Reviews
  • "Pillar[n]MaxQ: A New High Affinity Host Family for Sequestration in Water" (2020), published in Angewandte Chemie International Edition
  • "Voltage-Gated Membranes Incorporating Cucurbit[n]uril Molecular Containers for Molecular Nanofiltration" (2022), published in Journal of the American Chemical Society
  • "Biomedical applications of metal organic polygons and polyhedra (MOPs)" (2020), published in Coordination Chemistry Reviews
  • "Double-Cavity Nor-Seco-Cucurbit[10]uril Enables Efficient and Rapid Separation of Pyridine from Mixtures of Toluene, Benzene, and Pyridine" (2022), published in Angewandte Chemie International Edition

They have frequently collaborated with several coauthors, including:

  • Peter Y. Zavalij (21 publications)
  • Steven Murkli (12 publications)
  • David King (10 publications)
  • Chun-Lin Deng (7 publications)
  • Weijian Xue (7 publications)

Lyle Isaacs was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2013.

Best Publications

  • The cucurbit[n]uril family

    Jason Lagona;Pritam Mukhopadhyay;Sriparna Chakrabarti;Lyle Isaacs

  • The Cucurbit[n]uril Family: Prime Components for Self-Sorting Systems

    Simin Liu;Christian Ruspic;Pritam Mukhopadhyay;Sriparna Chakrabarti

  • A strategy for the generation of surfaces presenting ligands for studies of binding based on an active ester as a common reactive intermediate: a surface plasmon resonance study.

    Joydeep Lahiri;Lyle Isaacs;Joe Tien;George M. Whitesides

  • A synthetic host-guest system achieves avidin-biotin affinity by overcoming enthalpy-entropy compensation.

    Mikhail V. Rekharsky;Tadashi Mori;Cheng Yang;Young Ho Ko

  • Self-Sorting: The Exception or the Rule?

    Anxin Wu;Lyle Isaacs

  • Die Cucurbit[n]uril-Familie

    Jason Lagona;Pritam Mukhopadhyay;Sriparna Chakrabarti;Lyle Isaacs

  • Cucurbit[7]uril⋅guest pair with an attomolar dissociation constant

    Liping Cao;Marina Šekutor;Peter Y. Zavalij;Kata Mlinarić-Majerski

  • Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals

    Da Ma;Gaya Hettiarachchi;Duc Nguyen;Ben Zhang

  • Stimuli Responsive Systems Constructed Using Cucurbit[n]uril-Type Molecular Containers

    Lyle Isaacs

  • A Trivalent System from Vancomycin·d-Ala-d-Ala with Higher Affinity Than Avidin·Biotin

    Jianghong Rao;Joydeep Lahiri;Joydeep Lahiri;Lyle Isaacs;Lyle Isaacs;Robert M. Weis;Robert M. Weis

  • Improved purification of C60 and formation of σ- and π-homoaromatic methano-bridged fullerenes by reaction with alkyl diazoacetates

    Lyle Isaacs;Arno Wehrsig;François Diederich

  • Cucurbit[n]urils: from mechanism to structure and function

    Lyle Isaacs

  • Syntheses, structures, and properties of methanofullerenes

    François Diederich;Lyle Isaacs;Douglas Philp

  • Cucurbit[10]uril

    Simin Liu;Peter Y. Zavalij;Lyle Isaacs

  • Recognition-mediated activation of therapeutic gold nanoparticles inside living cells

    Chaekyu Kim;Sarit S. Agasti;Zhengjiang Zhu;Lyle Isaacs

  • Toxicology and Drug Delivery by Cucurbit[n]uril Type Molecular Containers

    Gaya Hettiarachchi;Duc Nguyen;Jing Wu;Derick Lucas

  • Tether-Directed Remote Functionalization of Buckminsterfullerene: Regiospecific Hexaadduct Formation†

    Lyle Isaacs;Richard F. Haldimann;François Diederich

  • Social Self-Sorting in Aqueous Solution

    Pritam Mukhopadhyay;Anxin Wu;Lyle Isaacs

  • Synthesis and Self-Assembly Processes of Monofunctionalized Cucurbit[7]uril

    Brittany Vinciguerra;Liping Cao;Joe R. Cannon;Peter Y. Zavalij

  • Nor-seco-cucurbit[10]uril exhibits homotropic allosterism.

    Wei-Hao Huang;Simin Liu;Peter Y. Zavalij;Lyle Isaacs

Frequent Co-Authors

Peter Y. Zavalij
Peter Y. Zavalij University of Maryland, College Park
An-Xin Wu
An-Xin Wu Central China Normal University
James C. Fettinger
James C. Fettinger University of California, Davis
Paul Seiler
Paul Seiler ETH Zurich
Corinne Boudon
Corinne Boudon University of Strasbourg
Kimoon Kim
Kimoon Kim Pohang University of Science and Technology
Maurice Gross
Maurice Gross Centre national de la recherche scientifique, CNRS
Jean-Paul Gisselbrecht
Jean-Paul Gisselbrecht University of Strasbourg
George M. Whitesides
George M. Whitesides Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Students pursuing Chemistry in the USA often explore related online degrees that can broaden their career opportunities. For those interested in a more specialized or interdisciplinary approach, online programs such as criminal justice offer practical applications in scientific investigations and regulatory compliance. Understanding the how much is a criminal justice degree can help prospective students budget effectively for their education.

Entry-level options like criminal justice associate programs online provide foundational knowledge that complements scientific research and lab work in chemistry-related fields, especially in forensic science.

For those inclined towards legal aspects of science, exploring degrees for paralegals can open pathways into intellectual property rights, patent law, and regulatory affairs associated with chemical products.

Additionally, Chemistry graduates can consider careers in the corporate sector, such as becoming a pharmaceutical sales representative. Understanding the pharmaceutical sales rep salary and career paths can provide valuable insights into this lucrative industry, combining scientific knowledge with business skills.

Best Scientists Citing Lyle Isaacs

Trending Scientists

Recently Published Articles