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Medicine

D-Index
108
Citations
67549
World Ranking
5877
National Ranking
219

Overview

John A. Foekens is affiliated with Erasmus University Rotterdam in the Netherlands and has a focused research portfolio within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work predominantly addresses topics related to Oncology, Cancer Research, and Molecular Biology, with additional engagement in Pathology and Forensic Medicine as well as Hepatology.

The scientist's research centers on multiple aspects of colorectal cancer and cancer genomics. Key topics in their studies include colorectal cancer treatments and surgical approaches, cancer-related molecular pathways, RNA modifications in cancer, genetic factors influencing colorectal cancer, and the roles of circular RNAs in disease processes.

Recent publications illustrate this concentration on cancer biology and molecular oncology. Notable papers include:

  • Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression, 2020, Oncogene
  • Interconnectivity between molecular subtypes and tumor stage in colorectal cancer, 2020, BMC Cancer
  • Circular RNA in Chemonaive Lymph Node Negative Colon Cancer Patients, 2021, Cancers
  • Interconnectivity between molecular subtypes and tumor stage in colorectal cancer, 2020, Research Square (Research Square)

Collaborative efforts are reflected through frequent co-authorship with researchers including Marcel Smid, John W.M. Martens, Robert R.J. Coebergh van den Braak, Saskia M. Wilting, and Sanne ten Hoorn. These partnerships have contributed to advancing knowledge within the cancer research domain.

Publication venues associated with Foekens's work represent journals specializing in oncology and cancer research:

  • Oncogene
  • BMC Cancer
  • Cancers
  • Research Square (Research Square)

Best Publications

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer.

    Yixin Wang;Jan G M Klijn;Yi Zhang;Anieta M Sieuwerts

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Genes that mediate breast cancer metastasis to the brain

    Paula D. Bos;Xiang H.-F. Zhang;Cristina Nadal;Weiping Shu

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series,

    Christine Desmedt;Fanny Piette;Sherene Loi;Yixin Wang

  • Subtypes of Breast Cancer Show Preferential Site of Relapse

    Marcel Smid;Yixin Wang;Yi Zhang;Anieta M. Sieuwerts

  • Young Age at Diagnosis Correlates With Worse Prognosis and Defines a Subset of Breast Cancers With Shared Patterns of Gene Expression

    Carey K. Anders;David S. Hsu;Gloria Broadwater;Chaitanya R. Acharya

  • Complex landscapes of somatic rearrangement in human breast cancer genomes.

    Philip J. Stephens;David J. Mcbride;Meng-lay Lin;Ignacio Varela

  • Definition of Clinically Distinct Molecular Subtypes in Estrogen Receptor–Positive Breast Carcinomas Through Genomic Grade

    Sherene Loi;Benjamin Haibe-Kains;Christine Desmedt;Françoise Lallemand

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • The Clinical Significance of Epidermal Growth Factor Receptor (EGF-R) in Human Breast Cancer: A Review on 5232 Patients

    J. G. M. Klijn;P. M. J. J. Berns;P. I. M. Schmitz;J. A. Foekens

  • Latent bone metastasis in breast cancer tied to Src-dependent survival signals.

    Xiang H.-F. Zhang;Qiongqing Wang;William Gerald;Clifford A. Hudis

  • Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients.

    Maxime P. Look;Wim L. J. van Putten;Michael J. Duffy;Nadia Harbeck

  • CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

    Hui Ling;Riccardo Spizzo;Yaser Atlasi;Milena Nicoloso

  • Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells

    Anieta M. Sieuwerts;Jaco Kraan;Joan Bolt;Petra van der Spoel

  • Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer

    John A. Foekens;Anieta M. Sieuwerts;Marcel Smid;Maxime P. Look

  • Lung metastasis genes couple breast tumor size and metastatic spread

    Andy J. Minn;Gaorav P. Gupta;David Padua;Paula Bos

Frequent Co-Authors

Anieta M. Sieuwerts
Anieta M. Sieuwerts Erasmus University Rotterdam
John W.M. Martens
John W.M. Martens Erasmus University Rotterdam
Jan G. M. Klijn
Jan G. M. Klijn Erasmus University Rotterdam
Marcel Smid
Marcel Smid Erasmus University Rotterdam
Stefan Sleijfer
Stefan Sleijfer Erasmus University Rotterdam
Manfred Schmitt
Manfred Schmitt Technical University of Munich
Fred C.G.J. Sweep
Fred C.G.J. Sweep Radboud University
Nils Brünner
Nils Brünner University of Copenhagen
Theo M. Luider
Theo M. Luider Erasmus University Rotterdam
Marc J. van de Vijver
Marc J. van de Vijver University of Amsterdam

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