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Medicine

D-Index
72
Citations
27838
World Ranking
19764
National Ranking
721

Overview

Anieta M. Sieuwerts is affiliated with Erasmus University Rotterdam in the Netherlands. Their research predominantly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on oncology and molecular biology subfields.

The scientist's work covers several specific subfields, including oncology, molecular biology, cancer research, pulmonary and respiratory medicine, and genetics. Their research topics prominently address areas such as cancer cells and metastasis, cancer genomics and diagnostics, prostate cancer treatment and research, PARP inhibition in cancer therapy, PI3K/AKT/mTOR signaling in cancer, colorectal cancer treatments and studies, and estrogen and related hormone effects.

Sieuwerts has coauthored numerous publications and frequently collaborates with several researchers:

  • John W.M. Martens
  • Stefan Sleijfer
  • Corine M. Beaufort
  • Maurice P.H.M. Jansen
  • Jaco Kraan

Their recent published papers include:

  • "Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer," 2020, published in Cell Stem Cell
  • "Generating human prostate cancer organoids from leukapheresis enriched circulating tumour cells," 2021, published in European Journal of Cancer
  • "Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests," 2022, published in Oncogene
  • "Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer," 2021, published in BMC Cancer
  • "ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen," 2020, published in Cancers

Publications by Sieuwerts have appeared most frequently in the journals BMC Cancer, European Journal of Cancer, Research Square, Cell Stem Cell, and Oncogene.

Best Publications

  • Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer.

    Yixin Wang;Jan G M Klijn;Yi Zhang;Anieta M Sieuwerts

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • Subtypes of Breast Cancer Show Preferential Site of Relapse

    Marcel Smid;Yixin Wang;Yi Zhang;Anieta M. Sieuwerts

  • Complex landscapes of somatic rearrangement in human breast cancer genomes.

    Philip J. Stephens;David J. Mcbride;Meng-lay Lin;Ignacio Varela

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

    Helen Davies;Dominik D. Glodzik;Sandro S. Morganella;Lucy R. Yates

  • CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

    Hui Ling;Riccardo Spizzo;Yaser Atlasi;Milena Nicoloso

  • Genomic Evolution of Breast Cancer Metastasis and Relapse

    Lucy R. Yates;Stian Knappskog;Stian Knappskog;David Wedge;David Wedge;James H.R. Farmery

  • Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells

    Anieta M. Sieuwerts;Jaco Kraan;Joan Bolt;Petra van der Spoel

  • Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer

    John A. Foekens;Anieta M. Sieuwerts;Marcel Smid;Maxime P. Look

  • Molecular Classification of Tamoxifen-Resistant Breast Carcinomas by Gene Expression Profiling

    Maurice P.H.M. Jansen;John A. Foekens;Iris L. van Staveren;Maaike M. Dirkzwager-Kiel

  • Multicenter Validation of a Gene Expression–Based Prognostic Signature in Lymph Node–Negative Primary Breast Cancer

    John A. Foekens;David Atkins;Yi Zhang;Fred C.G.J. Sweep

  • Genes Associated With Breast Cancer Metastatic to Bone

    Marcel Smid;Yixin Wang;Jan G.M. Klijn;Anieta M. Sieuwerts

  • Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

    Y S Ju;L B Alexandrov;M Gerstung;I Martincorena

  • The MTT tetrazolium salt assay scrutinized: how to use this assay reliably to measure metabolic activity of cell cultures in vitro for the assessment of growth characteristics, IC50-values and cell survival.

    Anieta M. Sieuwerts;Jan G. M. Klijn;Harry A. Peters;John A. Foekens

  • The topography of mutational processes in breast cancer genomes

    Sandro Morganella;Ludmil B. Alexandrov;Dominik Glodzik;Xueqing Zou

  • Efficacy of Cabazitaxel in Castration-resistant Prostate Cancer Is Independent of the Presence of AR-V7 in Circulating Tumor Cells

    Wendy Onstenk;Anieta M. Sieuwerts;Jaco Kraan;Mai Van

  • Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

    Arianna Fumagalli;Koen C. Oost;Koen C. Oost;Lennart Kester;Jessica Morgner

Frequent Co-Authors

John W.M. Martens
John W.M. Martens Erasmus University Rotterdam
John A. Foekens
John A. Foekens Erasmus University Rotterdam
Marcel Smid
Marcel Smid Erasmus University Rotterdam
Stefan Sleijfer
Stefan Sleijfer Erasmus University Rotterdam
Jan G. M. Klijn
Jan G. M. Klijn Erasmus University Rotterdam
Luc Dirix
Luc Dirix GZA Ziekenhuizen Campus Sint-Augustinus
Andrea L. Richardson
Andrea L. Richardson Johns Hopkins University
Serena Nik-Zainal
Serena Nik-Zainal University of Cambridge
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital

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