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Biology and Biochemistry

D-Index
61
Citations
12234
World Ranking
11440
National Ranking
4943

Overview

Jennifer K. Richer is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research primarily centers around molecular biology, oncology, and cancer research, with a significant focus on breast cancer and related hormone effects.

Their work spans several subfields, including molecular biology, oncology, pulmonary and respiratory medicine, and immunology. The topics addressed in their research cover a range of areas such as estrogen and related hormone effects, cancer cells and metastasis, advanced breast cancer therapies, immune cells in cancer, cancer genomics and diagnostics, breast cancer treatment studies, as well as cancer, hypoxia, and metabolism.

The scientist has contributed to numerous publications, appearing frequently in journals such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), the Journal of the Endocrine Society, Regular and Young Investigator Award Abstracts, and Cancers.

Some of their recent papers include:

  • Targeting Fatty Acid Oxidation to Promote Anoikis and Inhibit Ovarian Cancer Progression, 2020, Molecular Cancer Research
  • Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler, 2021, Cancers
  • Estrogen Receptor Alpha Mutations in Breast Cancer Cells Cause Gene Expression Changes through Constant Activity and Secondary Effects, 2020, Cancer Research
  • Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis, 2022, Cancer Research
  • ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation, 2022, Nature Communications

Jennifer K. Richer collaborates frequently with several co-authors, including:

  • Nicole S. Spoelstra
  • Michelle M. Williams
  • Jessica L. Christenson
  • Kathleen O'Neill
  • Lyndsey S. Crump

Best Publications

  • Nuclear Receptor Coactivators and Corepressors

    K B Horwitz;T A Jackson;D L Bain;J K Richer

  • Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells.

    Jennifer K. Richer;Britta M. Jacobsen;Nicole G. Manning;M. Greg Abel

  • The Partial Agonist Activity of Antagonist-Occupied Steroid Receptors Is Controlled by a Novel Hinge Domain-Binding Coactivator L7/SPA and the Corepressors N-CoR or SMRT

    Twila A. Jackson;Jennifer K. Richer;David L. Bain;Glenn S. Takimoto

  • Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.

    Gareth I. Owen;Jennifer K. Richer;Lin Tung;Glenn Takimoto

  • Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide.

    Dawn R Cochrane;Sebastián Bernales;Britta M Jacobsen;Diana M Cittelly

  • MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents

    Dawn R. Cochrane;Nicole S. Spoelstra;Erin N. Howe;Steven K. Nordeen

  • Targets of miR-200c mediate suppression of cell motility and anoikis resistance.

    Erin N Howe;Dawn R Cochrane;Jennifer K Richer

  • A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer.

    Nicholas C. D'Amato;Thomas J. Rogers;Michael A. Gordon;Lisa I. Greene

  • Convergence of progesterone with growth factor and cytokine signaling in breast cancer: Progesterone receptors regulate signal transducers and activators of transcription expression and activity

    Jennifer K. Richer;Carol A. Lange;Nicole G. Manning;Gareth Owen

  • Convergence of Progesterone and Epidermal Growth Factor Signaling in Breast Cancer POTENTIATION OF MITOGEN-ACTIVATED PROTEIN KINASE PATHWAYS

    Carol A. Lange;Jennifer K. Richer;Tianjie Shen;Kathryn B. Horwitz

  • HYPOTHESIS : PROGESTERONE PRIMES BREAST CANCER CELLS FOR CROSS-TALK WITH PROLIFERATIVE OR ANTIPROLIFERATIVE SIGNALS

    Carol A. Lange;Jennifer K. Richer;Kathryn B. Horwitz

  • Multiple molecular subtypes of triple-negative breast cancer critically rely on androgen receptor and respond to enzalutamide in vivo.

    Valerie N. Barton;Nicholas C. D'Amato;Michael A. Gordon;Hanne T. Lind

  • Downregulation of miR-342 is associated with tamoxifen resistant breast tumors

    Diana M Cittelly;Partha M Das;Nicole S Spoelstra;Susan M Edgerton

  • Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers.

    Dawn R. Cochrane;Erin N. Howe;Nicole S. Spoelstra;Jennifer K. Richer

  • The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers.

    Nicole S. Spoelstra;Nicole G. Manning;Yujiro Higashi;Douglas Darling

  • Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptor-positive breast cancer: PR isoform-specific gene regulation and tumor biology.

    Britta M. Jacobsen;Stephanie A. Schittone;Jennifer K. Richer;Kathryn B. Horwitz

  • ZEB1 expression in type I vs type II endometrial cancers : a marker of aggressive disease

    Meenakshi Singh;Nicole S Spoelstra;Annie Jean;Erin Howe

  • MicroRNAs Link Estrogen Receptor Alpha Status and Dicer Levels in Breast Cancer

    Dawn R. Cochrane;Diana M. Cittelly;Erin N. Howe;Nicole S. Spoelstra

  • Selective Down-Regulation of Progesterone Receptor Isoform B in Poorly Differentiated Human Endometrial Cancer Cells: Implications for Unopposed Estrogen Action

    Nirmala S. Kumar;Jennifer Richer;Gareth Owen;Elizabeth Litman

  • Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells

    S. A. Byron;K. B. Horwitz;J. K. Richer;Carol A Lange

Frequent Co-Authors

Kathryn B. Horwitz
Kathryn B. Horwitz University of Colorado Anschutz Medical Campus
Anthony D. Elias
Anthony D. Elias University of Colorado Boulder
Ann D. Thor
Ann D. Thor University of Colorado Anschutz Medical Campus
Steffi Oesterreich
Steffi Oesterreich University of Pittsburgh
Virginia F. Borges
Virginia F. Borges University of Colorado Boulder
Aaron Clauset
Aaron Clauset University of Colorado Boulder
Emanuel F. Petricoin
Emanuel F. Petricoin George Mason University
Dean P. Edwards
Dean P. Edwards Baylor College of Medicine
Travis Nemkov
Travis Nemkov University of Colorado Denver
Angelo D'Alessandro
Angelo D'Alessandro University of Colorado Denver

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