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Paul G. Higgins

Paul G. Higgins

D-Index & Metrics

Microbiology

D-Index
50
Citations
9664
World Ranking
4433
National Ranking
301

Overview

Paul G. Higgins is affiliated with the University of Cologne in Germany. Their primary research fields include Biochemistry, Genetics and Molecular Biology with 181 publications, and Medicine with 98 publications. Within these fields, they have contributed significantly to subfields such as Molecular Medicine, Endocrinology, Molecular Biology, Pharmacology, and Infectious Diseases.

The scientist's research focuses extensively on antibiotic resistance and related bacterial studies. Key topics covered in their work include:

  • Antibiotic Resistance in Bacteria
  • Vibrio bacteria research studies
  • Antibiotics Pharmacokinetics and Efficacy
  • Bacterial biofilms and quorum sensing
  • Bacterial Identification and Susceptibility Testing
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Bacteriophages and microbial interactions

Paul G. Higgins has published multiple papers in reputable scientific journals. Some recent notable papers include:

  • "Heavy Metal Toxicity in Armed Conflicts Potentiates AMR in A. baumannii by Selecting for Antibiotic and Heavy Metal Co-resistance Mechanisms" (2020), Frontiers in Microbiology
  • "A global view on carbapenem-resistant Acinetobacter baumannii" (2023), mBio
  • "In vitro activity of sulbactam/durlobactam against global isolates of carbapenem-resistant Acinetobacter baumannii" (2020), Journal of Antimicrobial Chemotherapy
  • "Molecular Epidemiology of Carbapenem-Resistant Acinetobacter baumannii From Khartoum State, Sudan" (2021), Frontiers in Microbiology
  • "Novel tigecycline resistance mechanisms in Acinetobacter baumannii mediated by mutations in adeS, rpoB and rrf" (2021), Emerging Microbes & Infections

They have also contributed to book literature, including a publication titled "Carbapenemase-Producing Organisms as Leading Cause of Hospital Infections" (2021) published by Frontiers Media.

The scientist frequently publishes in several venues, with the highest number of publications in:

  • Antibiotics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Microbiology
  • Journal of Antimicrobial Chemotherapy
  • Scientific Reports

Collaborations have been a notable part of their career, with frequent co-authors including:

  • Harald Seifert
  • Dhammika Leshan Wannigama
  • Shuichi Abe
  • Parichart Hongsing
  • Cameron Hurst

Best Publications

  • Global spread of carbapenem-resistant Acinetobacter baumannii

    Paul G Higgins;Cathrin Dammhayn;Meredith Hackel;Harald Seifert

  • OXA-143, a Novel Carbapenem-Hydrolyzing Class D β-Lactamase in Acinetobacter baumannii

    Paul G. Higgins;Laurent Poirel;Marlene Lehmann;Patrice Nordmann

  • OXA-235, a Novel Class D β-Lactamase Involved in Resistance to Carbapenems in Acinetobacter baumannii

    Paul G. Higgins;Francisco J. Pérez-Llarena;Esther Zander;Ana Fernández

  • Molecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007

    Yvonne Pfeifer;Gottfried Wilharm;Esther Zander;Thomas A. Wichelhaus

  • Nosocomial bloodstream infections due to Acinetobacter baumannii, Acinetobacter pittii and Acinetobacter nosocomialis in the United States

    Hilmar Wisplinghoff;Tobias Paulus;Marianne Lugenheim;Danuta Stefanik

  • High incidence of pandrug-resistant Acinetobacter baumannii isolates collected from patients with ventilator-associated pneumonia in Greece, Italy and Spain as part of the MagicBullet clinical trial.

    J Nowak;E Zander;D Stefanik;P G Higgins

  • Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-β-naphthylamide

    Stefanie Pannek;Paul G. Higgins;Petra Steinke;Daniel Jonas

  • Inclusion of OXA-143 primers in a multiplex polymerase chain reaction (PCR) for genes encoding prevalent OXA carbapenemases in Acinetobacter spp.

    Paul G. Higgins;Marlene Lehmann;Harald Seifert

  • Selection of topoisomerase mutations and overexpression of adeB mRNA transcripts during an outbreak of Acinetobacter baumannii.

    Paul G. Higgins;Hilmar Wisplinghoff;Danuta Stefanik;Harald Seifert

  • In Vitro Activities of the β-Lactamase Inhibitors Clavulanic Acid, Sulbactam, and Tazobactam Alone or in Combination with β-Lactams against Epidemiologically Characterized Multidrug-Resistant Acinetobacter baumannii Strains

    Paul G. Higgins;Hilmar Wisplinghoff;Danuta Stefanik;Harald Seifert

  • A PCR-based method to differentiate between Acinetobacter baumannii and Acinetobacter genomic species 13TU

    P.G. Higgins;H. Wisplinghoff;O. Krut;H. Seifert

  • Mutations in GyrA, ParC, MexR and NfxB in clinical isolates of Pseudomonas aeruginosa

    P.G. Higgins;A.C. Fluit;D. Milatovic;J. Verhoef

  • Development and evaluation of a core genome multilocus typing scheme for whole-genome sequence-based typing of Acinetobacter baumannii.

    Paul G. Higgins;Karola Prior;Dag Harmsen;Harald Seifert

  • Acinetobacter seifertii sp. nov., a member of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex isolated from human clinical specimens.

    Alexandr Nemec;Lenka Krizova;Martina Maixnerova;Ondrej Sedo

  • gyrB Multiplex PCR To Differentiate between Acinetobacter calcoaceticus and Acinetobacter Genomic Species 3

    Paul G. Higgins;Marlene Lehmann;Hilmar Wisplinghoff;Harald Seifert

  • Fluoroquinolones: structure and target sites.

    P. G. Higgins;A. C. Fluit;F J. Schmitz

  • Heavy metal toxicity in armed conflicts potentiates AMR in A. baumannii by selecting for antibiotic and heavy metal co-resistance mechanisms

    Wael Bazzi;Wael Bazzi;Antoine G. Abou Fayad;Antoine G. Abou Fayad;Aya Nasser;Aya Nasser;Louis-Patrick Haraoui

  • Outbreak of carbapenem-resistant Acinetobacter baumannii carrying the carbapenemase OXA-23 in a German university medical centre

    Anke Kohlenberg;Sophie Brümmer;Paul G. Higgins;Dorit Sohr

  • In-vitro activity of the novel fluorocycline eravacycline against carbapenem non-susceptible Acinetobacter baumannii

    Harald Seifert;Danuta Stefanik;Joyce A. Sutcliffe;Paul G. Higgins

  • A global view on carbapenem-resistant Acinetobacter baumannii

    Unknown

  • Characterization of RarA, a Novel AraC Family Multidrug Resistance Regulator in Klebsiella pneumoniae

    Mark Veleba;Paul G. Higgins;Gerardo Gonzalez;Harald Seifert

Frequent Co-Authors

Harald Seifert
Harald Seifert University of Cologne
Hilmar Wisplinghoff
Hilmar Wisplinghoff University of Cologne
Robert A. Bonomo
Robert A. Bonomo Case Western Reserve University
Andrea M. Hujer
Andrea M. Hujer United States Department of Veterans Affairs
Kristine M. Hujer
Kristine M. Hujer Case Western Reserve University
Jordi Vila
Jordi Vila University of Barcelona
Michael R. Jacobs
Michael R. Jacobs University Hospitals of Cleveland
Holger Rohde
Holger Rohde Universität Hamburg
Barry N. Kreiswirth
Barry N. Kreiswirth Center for Discovery and Innovation
Axel Hamprecht
Axel Hamprecht University of Cologne

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