D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 20,923 129 World Ranking 6877 National Ranking 3195

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Rong Wang focuses on Endocrinology, Internal medicine, Biochemistry, Amyloid and Cell biology. The various areas that he examines in his Endocrinology study include Alzheimer's disease, Amyloid precursor protein secretase, Amyloid precursor protein and Genetically modified mouse. Rong Wang has researched Genetically modified mouse in several fields, including Pathogenesis and Pathology.

His work on Presenilin and Semagacestat as part of general Internal medicine study is frequently connected to Indometacin, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His study in Amyloid is interdisciplinary in nature, drawing from both Caloric theory, β amyloid and Beta. Rong Wang has included themes like Guanosine, Cell culture, Transmembrane domain and Cytosol in his Cell biology study.

His most cited work include:

  • Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo (1356 citations)
  • A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity (1286 citations)
  • Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. (874 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Cell biology, Amyloid precursor protein, Presenilin and Peptide. His work in Biochemistry addresses subjects such as Amyloid precursor protein secretase, which are connected to disciplines such as Gamma secretase. He interconnects Secretion, Receptor and Neuroscience in the investigation of issues within Cell biology.

His Amyloid precursor protein research is multidisciplinary, incorporating perspectives in Molecular biology and Amyloid. His studies deal with areas such as Endocrinology, Genetically modified mouse and Beta as well as Amyloid. His Presenilin research incorporates themes from Genetics and Mutant.

He most often published in these fields:

  • Biochemistry (35.94%)
  • Cell biology (28.12%)
  • Amyloid precursor protein (18.75%)

What were the highlights of his more recent work (between 2010-2017)?

  • Biochemistry (35.94%)
  • Amyloid precursor protein (18.75%)
  • Cell biology (28.12%)

In recent papers he was focusing on the following fields of study:

Rong Wang spends much of his time researching Biochemistry, Amyloid precursor protein, Cell biology, Regulation of gene expression and Chromatography. The study incorporates disciplines such as P3 peptide and Amyloid in addition to Biochemistry. The concepts of his Amyloid precursor protein study are interwoven with issues in Neurogenesis and Neuroscience.

His Cell biology study incorporates themes from Secretion, Postsynaptic potential and Immunology. His Regulation of gene expression research incorporates elements of Endocrinology, Gene expression and Gene knockdown. His Amyloid precursor protein secretase research is multidisciplinary, incorporating elements of Black cohosh, Toxicity, Gamma secretase and Presenilin.

Between 2010 and 2017, his most popular works were:

  • Coordination of m 6 A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming (146 citations)
  • Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model (84 citations)
  • Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain (56 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Rong Wang mostly deals with Biochemistry, Amyloid precursor protein, Amyloid precursor protein secretase, Cell biology and Neuroscience. His research integrates issues of P3 peptide, Presenilin and Senile plaques in his study of Biochemistry. His Amyloid precursor protein research is multidisciplinary, relying on both Gamma secretase and Aminothiazole.

His work deals with themes such as Black cohosh, Natural product, Toxicity and Peptide, which intersect with Amyloid precursor protein secretase. In his study, Amyloid and PI3K/AKT/mTOR pathway is strongly linked to Neurotoxicity, which falls under the umbrella field of Cell biology. His Neuroscience research integrates issues from Huntingtin and Genetically modified mouse.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David R. Borchelt;Gopal Thinakaran;Christopher B. Eckman;Christopher B. Eckman;Michael K. Lee.
Neuron (1996)

1985 Citations

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Sascha Weggen;Jason L. Eriksen;Pritam Das;Sarah A. Sagi.
Nature (2001)

1805 Citations

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model.

Lorenzo M. Refolo;Miguel A. Pappolla;Brian Malester;John LaFrancois.
Neurobiology of Disease (2000)

1252 Citations

Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.

A E Roher;J D Lowenson;S Clarke;C Wolkow.
Journal of Biological Chemistry (1993)

874 Citations

Proteomic Analysis of Proteins Associated with Lipid Droplets of Basal and Lipolytically Stimulated 3T3-L1 Adipocytes *

Dawn L. Brasaemle;Georgia Dolios;Lawrence Shapiro;Rong Wang.
Journal of Biological Chemistry (2004)

846 Citations

A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

L. M. Refolo;Miguel Pappolla;J. LaFrancois;B. Malester.
Neurobiology of Disease (2001)

684 Citations

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.

Huaxi Xu;Gunnar K. Gouras;Jeffrey P. Greenfield;Bruno Vincent.
Nature Medicine (1998)

672 Citations

Aβ42 Is Essential for Parenchymal and Vascular Amyloid Deposition in Mice

Eileen McGowan;Fiona Pickford;Jungsu Kim;Luisa Onstead.
Neuron (2005)

652 Citations

Stimulation of β-Amyloid Precursor Protein Trafficking by Insulin Reduces Intraneuronal β-Amyloid and Requires Mitogen-Activated Protein Kinase Signaling

Laura Gasparini;Gunnar K. Gouras;Rong Wang;Rachel S. Gross.
The Journal of Neuroscience (2001)

583 Citations

Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.

Yue Qi-Takahara;Maho Morishima-Kawashima;Yu Tanimura;Georgia Dolios.
The Journal of Neuroscience (2005)

458 Citations

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