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Biology and Biochemistry

D-Index
74
Citations
18529
World Ranking
5629
National Ranking
2674

Research.com Recognitions

  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Michael C. Ostrowski is affiliated with the Medical University of South Carolina in the United States. Their research primarily focuses on medicine, with significant contributions in biochemistry, genetics, and molecular biology. Within these broader fields, their work concentrates on oncology, molecular biology, cancer research, physiology, and surgery.

Their research spans several main topics, including pancreatic and hepatic oncology research, cancer cells and metastasis, epigenetics and DNA methylation, cancer genomics and diagnostics, nutrition and health in aging, pancreatic function and diabetes, and muscle physiology and disorders.

Recent research publications include:

  • The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis, 2023, Nature Communications
  • PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis, 2021, Nature Communications
  • Stromal Platelet-Derived Growth Factor Receptor-β Signaling Promotes Breast Cancer Metastasis in the Brain, 2020, Cancer Research
  • STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer, 2022, Life Science Alliance
  • Cancer cachexia: involvement of an expanding macroenvironment, 2023, Cancer Cell

The scientist has collaborated frequently with several co-authors, including:

  • Julia E. Lefler
  • Gustavo Leone
  • Sudarshana M. Sharma
  • Cynthia Timmers
  • Teresa A. Zimmers

Publication venues where Michael C. Ostrowski has contributed multiple papers include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Molecular Cancer Research

Michael C. Ostrowski was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2004.

Best Publications

  • Ambient Air Pollution Exaggerates Adipose Inflammation and Insulin Resistance in a Mouse Model of Diet-Induced Obesity

    Qinghua Sun;Peibin Yue;Jeffrey A. Deiuliis;Carey N. Lumeng

  • A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse.

    R. Tedjo Sasmono;Delvac Oceandy;Jeffrey W. Pollard;Wei Tong

  • Pten in stromal fibroblasts suppresses mammary epithelial tumours

    Anthony J. Trimboli;Carmen Z. Cantemir-Stone;Fu Li;Julie A. Wallace

  • MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells.

    Jakub Godlewski;Michal O. Nowicki;Agnieszka Bronisz;Gerard Nuovo

  • Direct evidence for Epithelial-Mesenchymal transitions in breast cancer

    Anthony J. Trimboli;Koichi Fukino;Alain de Bruin;Guo Wei

  • IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer

    Thomas A Mace;Reena Shakya;Jason R Pitarresi;Benjamin Swanson

  • Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2.

    Beom-Seok Yang;C. A. Hauser;G. Henkel;M. S. Colman

  • Extra-embryonic function of Rb is essential for embryonic development and viability.

    Lizhao Wu;Alain de Bruin;Harold I. Saavedra;Maja Starovic

  • NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism

    Antonios O. Aliprantis;Yasuyoshi Ueki;Rosalyn Sulyanto;Arnold Park

  • Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells.

    Fan Pan;Hong Yu;Eric V. Dang;Joseph Barbi

  • Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus.

    Ann L. Huang;Michael C. Ostrowski;Diana Berard;Gordon L. Hager

  • Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320

    A. Bronisz;J. Godlewski;J. A. Wallace;A.S. Merchant

  • Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-κB ligand signaling

    Kim C. Mansky;Uma Sankar;Jiahuai Han;Michael C. Ostrowski

  • The ETS family of oncogenic transcription factors in solid tumours

    Gina M. Sizemore;Jason R. Pitarresi;Subhasree Balakrishnan;Michael C. Ostrowski

  • Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1

    Agnieszka Bronisz;Agnieszka Bronisz;Yan Wang;Michal O. Nowicki;Michal O. Nowicki;Pierpaolo Peruzzi

  • Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1.

    S A McCarthy;D Chen;B S Yang;J J Garcia Ramirez

  • Differentiation of the Mononuclear Phagocyte System During Mouse Embryogenesis: The Role of Transcription Factor PU.1

    Agnieszka M. Lichanska;Catherine M. Browne;Catherine M. Browne;Catherine M. Browne;Gregory W. Henkel;Gregory W. Henkel;Gregory W. Henkel;Kathleen M. Murphy;Kathleen M. Murphy;Kathleen M. Murphy

  • Purification and cell-free synthesis of a major protein from rat seminal vesicle secretion. A potential marker for androgen action.

    M C Ostrowski;M K Kistler;W S Kistler

  • Transgenic mice overexpressing tartrate-resistant acid phosphatase exhibit an increased rate of bone turnover.

    N Z Angel;N Walsh;M R Forwood;M C Ostrowski

  • Macrophage Colony-stimulating Factor Promotes Cell Survival through Akt/Protein Kinase B

    Todd W. Kelley;Mandy M. Graham;Andrea I. Doseff;Richard W. Pomerantz

Frequent Co-Authors

Gustavo Leone
Gustavo Leone Medical University of South Carolina
David A. Hume
David A. Hume University of Queensland
Balveen Kaur
Balveen Kaur Augusta University
Charis Eng
Charis Eng Cleveland Clinic Lerner College of Medicine
Charles L. Shapiro
Charles L. Shapiro Icahn School of Medicine at Mount Sinai
Clay B. Marsh
Clay B. Marsh West Virginia University
Susheela Tridandapani
Susheela Tridandapani The Ohio State University
Denis C. Guttridge
Denis C. Guttridge Medical University of South Carolina
Robert Pilarski
Robert Pilarski Ambry Genetics (United States)
Sean E. Lawler
Sean E. Lawler Brown University

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