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Sigrid C. J. De Keersmaecker

Sigrid C. J. De Keersmaecker

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
12165
World Ranking
17010
National Ranking
285

Overview

Sigrid C. J. De Keersmaecker is affiliated with KU Leuven in Belgium and has made contributions primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their scholarly output includes over 100 publications in these domains, with notable subfields including Molecular Biology, Infectious Diseases, Ecology, Food Science, and Epidemiology.

The research scope of De Keersmaecker spans diverse topics, highlighting work in:

  • Bacteriophages and microbial interactions
  • Genomics and Phylogenetic Studies
  • Antibiotic Resistance in Bacteria
  • Salmonella and Campylobacter epidemiology
  • Identification and Quantification in Food
  • Bacterial Identification and Susceptibility Testing
  • Escherichia coli research studies

Their recent publications exemplify the focus on microbiology, genetics, and antimicrobial resistance, including:

  • Combining short and long read sequencing to characterize antimicrobial resistance genes on plasmids applied to an unauthorized genetically modified Bacillus, 2020, Scientific Reports
  • Closing the gap: Oxford Nanopore Technologies R10 sequencing allows comparable results to Illumina sequencing for SNP-based outbreak investigation of bacterial pathogens, 2024, Journal of Clinical Microbiology
  • Large diversity of linezolid-resistant isolates discovered in food-producing animals through linezolid selective monitoring in Belgium in 2019, 2021, Journal of Antimicrobial Chemotherapy
  • Comparison of 6 DNA extraction methods for isolation of high yield of high molecular weight DNA suitable for shotgun metagenomics Nanopore sequencing to detect bacteria, 2023, BMC Genomics
  • Genomic epidemiology of emerging ESBL-producing Salmonella Kentucky bla CTX-M-14b in Europe, 2020, Emerging Microbes & Infections

The scientist has frequently published in venues including Frontiers in Microbiology, Microbial Genomics, Scientific Reports, Food Chemistry Molecular Sciences, and Foods.

Collaboration is an evident aspect of their research activities, with frequent coauthors such as Nancy H. C. Roosens, Kevin Vanneste, Bert Bogaerts, Kathleen Marchal, and Bavo Verhaegen. These partnerships indicate a network centered around microbiology, genetics, and pathogen research.

Best Publications

  • Genes and Molecules of Lactobacilli Supporting Probiotic Action

    Sarah Lebeer;Jos Vanderleyden;Sigrid C. J. De Keersmaecker

  • Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens

    Sarah Lebeer;Jos Vanderleyden;Sigrid C. J. De Keersmaecker

  • Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein

    Matti Kankainen;Lars Paulin;Soile Tynkkynen;Ingemar von Ossowski

  • Salmonella biofilms: An overview on occurrence, structure, regulation and eradication

    Hans Steenackers;Kim Hermans;Jos Vanderleyden;Sigrid C.J. De Keersmaecker

  • Strong antimicrobial activity of Lactobacillus rhamnosus GG against Salmonella typhimurium is due to accumulation of lactic acid

    Sigrid C.J. De Keersmaecker;Tine L.A. Verhoeven;Jos Desair;Kathleen Marchal

  • Functional Analysis of Lactobacillus rhamnosus GG Pili in Relation to Adhesion and Immunomodulatory Interactions with Intestinal Epithelial Cells

    Sarah Lebeer;Sarah Lebeer;Ingmar Claes;Hanne L. P. Tytgat;Tine L. A. Verhoeven

  • Identification of a Gene Cluster for the Biosynthesis of a Long, Galactose-Rich Exopolysaccharide in Lactobacillus rhamnosus GG and Functional Analysis of the Priming Glycosyltransferase

    Sarah Lebeer;Tine L. A. Verhoeven;Grégory Francius;Geert Schoofs

  • Impact of Environmental and Genetic Factors on Biofilm Formation by the Probiotic Strain Lactobacillus rhamnosus GG

    Sarah Lebeer;Tine L. A. Verhoeven;Mónica Perea Vélez;Jos Vanderleyden

  • Brominated furanones inhibit biofilm formation by Salmonella enterica serovar Typhimurium.

    Joost C. A. Janssens;Hans Steenackers;Stijn Robijns;Edith Gellens

  • Adherence factors of Lactobacillus in the human gastrointestinal tract

    Mónica Perea Vélez;Sigrid C.J. De Keersmaecker;Jos Vanderleyden

  • Let LuxS speak up in AI-2 signaling

    Sigrid C.J. De Keersmaecker;Kathleen Sonck;Jos Vanderleyden

  • Exopolysaccharides of Lactobacillus rhamnosus GG form a protective shield against innate immune factors in the intestine.

    Sarah Lebeer;Ingmar J. J. Claes;Tine L. A. Verhoeven;Jos Vanderleyden

  • Detection, localization, and conformational analysis of single polysaccharide molecules on live bacteria.

    Gregory Francius;Sarah Lebeer;David Alsteens;Linda Wildling

  • Concise and Diversity-Oriented Route toward Polysubstituted 2-Aminoimidazole Alkaloids and Their Analogues

    Denis S. Ermolat'ev;Jitender B. Bariwal;Hans P. L. Steenackers;Sigrid C. J. De Keersmaecker

  • A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2

    Ines Thiele;Daniel R Hyduke;Benjamin Steeb;Guy Fankam

  • Functional Analysis of luxS in the Probiotic Strain Lactobacillus rhamnosus GG Reveals a Central Metabolic Role Important for Growth and Biofilm Formation

    Sarah Lebeer;Sigrid C. J. De Keersmaecker;Tine L. A. Verhoeven;Abeer A. Fadda

  • Chemical Synthesis of (S)-4,5-Dihydroxy-2,3-pentanedione, a Bacterial Signal Molecule Precursor, and Validation of Its Activity in Salmonella typhimurium

    Sigrid C.J. De Keersmaecker;Csaba Varszegi;Nadja van Boxel;Lothar W. Habel

  • TARGETING THE 16S RRNA GENE FOR BACTERIAL IDENTIFICATION IN COMPLEX MIXED SAMPLES: COMPARATIVE EVALUATION OF SECOND (ILLUMINA) AND THIRD (OXFORD NANOPORE TECHNOLOGIES) GENERATION SEQUENCING TECHNOLOGIES.

    Raf Winand;Bert Bogaerts;Stefan Hoffman;Loïc Lefevre

  • Comparison of the PhoPQ Regulon in Escherichia coli and Salmonella typhimurium

    Pieter Monsieurs;Sigrid Cj De Keersmaecker;William W Navarre;Martin W Bader

  • Functional Analysis of d-Alanylation of Lipoteichoic Acid in the Probiotic Strain Lactobacillus rhamnosus GG

    Mónica Perea Vélez;Tine L. A. Verhoeven;Christian Draing;Sonja Von Aulock

Frequent Co-Authors

Kathleen Marchal
Kathleen Marchal Ghent University
Sarah Lebeer
Sarah Lebeer University of Antwerp
Dirk De Vos
Dirk De Vos KU Leuven
Willem M. de Vos
Willem M. de Vos Wageningen University & Research
Bart De Moor
Bart De Moor KU Leuven
Denis Piérard
Denis Piérard Vrije Universiteit Brussel
Airi Palva
Airi Palva University of Helsinki
Dieter Deforce
Dieter Deforce Ghent University

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