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Genetics

D-Index
48
Citations
25659
World Ranking
4018
National Ranking
1734

Overview

Robert Pilarski is affiliated with Ambry Genetics in the United States and has contributed extensively to research in the fields of biochemistry, genetics, and molecular biology. Their work primarily focuses on genetics, with significant involvement in molecular biology, pathology and forensic medicine, cancer research, and oncology.

Their research interests emphasize several main topics, including:

  • BRCA gene mutations in cancer
  • Genomics and rare diseases
  • Genetic factors in colorectal cancer
  • Cancer genomics and diagnostics
  • Nutrition, genetics, and disease
  • DNA repair mechanisms
  • PARP inhibition in cancer therapy

Robert Pilarski has published in various scientific venues, with a concentration in:

  • Journal of the National Comprehensive Cancer Network
  • Cancer Research
  • Familial Cancer
  • Genetics in Medicine Open
  • Journal of Clinical Oncology

Recent papers authored by or involving Robert Pilarski include:

  • "NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020" (2020), Journal of the National Comprehensive Cancer Network
  • "Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019" (2020), Journal of Clinical Oncology
  • "Splicing profile by capture RNA-seq identifies pathogenic germline variants in tumor suppressor genes" (2020), npj Precision Oncology
  • "Stromal Platelet-Derived Growth Factor Receptor-β Signaling Promotes Breast Cancer Metastasis in the Brain" (2020), Cancer Research
  • "Mutational and splicing landscape in a cohort of 43,000 patients tested for hereditary cancer" (2022), npj Genomic Medicine

Frequent collaborators in their research include colleagues such as:

  • Lily Hoang
  • Amanda E. Toland
  • Bhuvaneswari Ramaswamy
  • Carolyn Horton
  • Susan M. Domchek

Best Publications

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

    A. Gordon Robertson;Juliann Shih;Juliann Shih;Christina Yau;Ewan A. Gibb

  • Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.

    André Kahles;Kjong-Van Lehmann;Nora C Toussaint;Matthias Hüser

  • Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

    Butler Mg;Dasouki Mj;Zhou Xp;Talebizadeh Z

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Inherited Mutations in 17 Breast Cancer Susceptibility Genes Among a Large Triple-Negative Breast Cancer Cohort Unselected for Family History of Breast Cancer

    Fergus J. Couch;Steven N. Hart;Priyanka Sharma;Amanda Ewart Toland

  • Cowden Syndrome and the PTEN Hamartoma Tumor Syndrome: Systematic Review and Revised Diagnostic Criteria

    Robert Pilarski;Randall Burt;Wendy Kohlman;Lana Pho

  • NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017.

    Mary B. Daly;Robert Pilarski;Michael Berry;Saundra S. Buys

  • Genetic/familial high-risk assessment: breast and ovarian.

    Mary B. Daly;Jennifer E. Axilbund;Saundra Buys;Beth Crawford

  • BRCA1 Sequence Analysis in Women at High Risk for Susceptibility Mutations: Risk Factor Analysis and Implications for Genetic Testing

    Donna Shattuck-Eidens;Arnold Oliphant;Melody McClure;Celeste McBride

  • Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers

    Mohamed H Abdel-Rahman;Robert Pilarski;Colleen M Cebulla;James B Massengill

  • Genome-wide association studies identify four ER negative-specific breast cancer risk loci

    Montserrat Garcia-Closas;Fergus J. Couch;Sara Lindstrom;Kyriaki Michailidou

  • NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020.

    Mary B. Daly;Robert Pilarski;Matthew B. Yurgelun;Michael P. Berry

  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi

  • Will the real Cowden syndrome please stand up (again)? Expanding mutational and clinical spectra of the PTEN hamartoma tumour syndrome

    R Pilarski;C Eng

  • Germline PTEN Promoter Mutations and Deletions in Cowden/Bannayan-Riley-Ruvalcaba Syndrome Result in Aberrant PTEN Protein and Dysregulation of the Phosphoinositol-3-Kinase/Akt Pathway

    Xiao Ping Zhou;Kristin A. Waite;Robert Pilarski;Heather Hampel

  • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma (vol 32, pg 204, 2017)

    A.G. Robertson;J.L. Shih;C. Yau;E.A. Gibb

Frequent Co-Authors

Charis Eng
Charis Eng Cleveland Clinic Lerner College of Medicine
Charles L. Shapiro
Charles L. Shapiro Icahn School of Medicine at Mount Sinai
Elizabeth M. Swisher
Elizabeth M. Swisher University of Washington
Mary B. Daly
Mary B. Daly Fox Chase Cancer Center
Peter A. Fasching
Peter A. Fasching University of Erlangen-Nuremberg
Kenneth Offit
Kenneth Offit Memorial Sloan Kettering Cancer Center
Andrew D. Cherniack
Andrew D. Cherniack Broad Institute
Judy Garber
Judy Garber Harvard University
Amanda E. Toland
Amanda E. Toland The Ohio State University
Nicholas K. Hayward
Nicholas K. Hayward QIMR Berghofer Medical Research Institute

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Related Online Degrees & Career Pathways

Studying Genetics provides a solid foundation for a diverse range of healthcare and science careers. In addition to lab-based roles, many students explore related fields that can be pursued through accessible online programs. For those interested in administration, enrolling in comprehensive healthcare administration programs or pursuing an online health management degree can open doors to leadership positions in hospitals and research institutions.

Others may choose patient-care tracks, considering options like attending a nursing school with high acceptance rate to begin a healthcare career with greater flexibility and job security. Additionally, students seeking specialized roles with less clinical focus might look into earning medical coder certification to support health organizations on the administrative side.

These pathways allow Genetics graduates—and those with related interests—to pursue further specialization, adapt to evolving industry demands, and discover the best fit for their skills within the broad healthcare sector.

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