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Immunology

D-Index
67
Citations
16983
World Ranking
2660
National Ranking
1271

Overview

Iqbal S. Grewal is affiliated with Johnson & Johnson in the United States and has contributed extensively to medical research, particularly within the field of medicine. Their work chiefly centers on oncology, immunology, pathology and forensic medicine, pulmonary and respiratory medicine, along with radiology, nuclear medicine, and imaging. The primary field of medicine comprises 29 publications, highlighting a significant focus on health sciences.

Within these domains, Grewal's subfield specializations include:

  • Oncology
  • Immunology
  • Pathology and Forensic Medicine
  • Pulmonary and Respiratory Medicine
  • Radiology, Nuclear Medicine and Imaging

The research topics that Grewal has extensively explored involve CAR-T cell therapy, immune cell function, monoclonal and polyclonal antibodies research, immunotherapy, virus-based gene therapy, cancer lesions, and breast carcinomas. The main topics covered by their publications are:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Monoclonal and Polyclonal Antibodies Research
  • Immunotherapy and Immune Responses
  • Virus-based gene therapy research
  • Cancer and Skin Lesions
  • Breast Lesions and Carcinomas

Some of the frequent publication venues where Grewal's works appeared include:

  • Clinical Case Reports and Studies
  • Cureus
  • European Journal of Immunology
  • British Journal of Cancer
  • Molecular Cancer Therapeutics

Recent notable papers authored or coauthored by Grewal demonstrate a focus on immunotherapy and cancer treatment strategies. These works are:

  • Regulatory T cell targeting in cancer: Emerging strategies in immunotherapy, 2020, European Journal of Immunology
  • Overcoming the challenges associated with CD3+ T-cell redirection in cancer, 2021, British Journal of Cancer
  • Emerging CAR-T Cell Therapy for the Treatment of Triple-Negative Breast Cancer, 2020, Molecular Cancer Therapeutics
  • Selective recruitment of γδ T cells by a bispecific antibody for the treatment of acute myeloid leukemia, 2021, Leukemia
  • Bispecific Antibodies for Triple Negative Breast Cancer, 2020, Trends in cancer

Iqbal S. Grewal collaborates frequently with a number of researchers in their field. Among the most common coauthors are:

  • Sanjaya Singh
  • Rajkumar Ganesan
  • Sundee Dees
  • Omar Elsemary
  • Saifullah Nasim

Best Publications

  • CD40 and CD154 in cell-mediated immunity.

    Iqbal S. Grewal;Richard A. Flavell

  • BAFF/BLyS Receptor 3 Binds the B Cell Survival Factor BAFF Ligand through a Discrete Surface Loop and Promotes Processing of NF-κB2

    Nobuhiko Kayagaki;Minhong Yan;Dhaya Seshasayee;Hua Wang

  • Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand.

    Iqbal S. Grewal;Jianchao Xu;Richard A. Flavell

  • The Role of CD40 Ligand in Costimulation and T‐Cell Activation

    Iqbal S. Grewal;Richard A. Flavell

  • Requirement for CD154 in the progression of atherosclerosis.

    Lutgens E;Gorelik L;Daemen Mj;de Muinck Ed

  • Activation and accumulation of B cells in TACI-deficient mice

    Minhong Yan;Hua Wang;Betty Chan;Meron Roose-Girma

  • Development of Th1-type immune responses requires the type I cytokine receptor TCCR

    Chen Q;Ghilardi N;Wang H;Baker T

  • Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis

    Iqbal S. Grewal;Harald G. Foellmer;Kate D. Grewal;Jianchao Xu

  • Loss of TACI Causes Fatal Lymphoproliferation and Autoimmunity, Establishing TACI as an Inhibitory BLyS Receptor

    Dhaya Seshasayee;Patricia Valdez;Minhong Yan;Vishva M Dixit

  • Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency.

    Minhong Yan;John Ridgway Brady;Betty Chan;Wyne P. Lee

  • A central role of CD40 ligand in the regulation of CD4+ T-cell responses

    Iqbal S. Grewal;Richard A. Flavell

  • Disruption of CD40–CD40 Ligand Interactions Results in an Enhanced Susceptibility to Leishmania amazonensis Infection

    Lynn Soong;Jian Chao Xu;Iqbal S. Grewal;Peter Kima

  • CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.

    P. Borrow;A. Tishon;S. Lee;J. Xu

  • Impaired T cell-mediated macrophage activation in CD40 ligand-deficient mice.

    R. D. Stout;J. Suttles;Jianchao Xu;I. S. Grewal

  • Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity.

    Minhong Yan;Scot A. Marsters;Iqbal S. Grewal;Hua Wang

  • TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice.

    Hua Wang;Scot A. Marsters;Thad Baker;Betty Chan

  • Antibody targeting of B-cell maturation antigen on malignant plasma cells

    Maureen C. Ryan;Michelle Hering;David Peckham;Charlotte F. McDonagh

  • APRIL-Deficient Mice Have Normal Immune System Development

    Eugene Varfolomeev;Frank Kischkel;Flavius Martin;Dhaya Seshasayee

  • Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells.

    I S Grewal;K D Grewal;F S Wong;D E Picarella

  • In vivo properties of monocyte chemoattractant protein-1.

    Long Gu;Barbara Rutledge;Joseph Fiorillo;Catherine Ernst

Frequent Co-Authors

Richard A. Flavell
Richard A. Flavell Yale University
Wyne P. Lee
Wyne P. Lee Genentech
Hans-Peter Gerber
Hans-Peter Gerber Seattle Genetics (United States)
Charles A. Janeway
Charles A. Janeway Yale University
Steven P. Treon
Steven P. Treon Harvard University
F. Susan Wong
F. Susan Wong Cardiff University

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