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Microbiology

D-Index
59
Citations
15791
World Ranking
3231
National Ranking
53

Overview

Hans O. Madsen is affiliated with Copenhagen University Hospital in Denmark and has contributed extensively to the field of Medicine, with a particular focus on Hematology. Their research spans multiple subfields including Public Health, Environmental and Occupational Health, Genetics, Molecular Biology, and Immunology.

Their primary research topics encompass Acute Lymphoblastic Leukemia research, Hematopoietic Stem Cell Transplantation, Acute Myeloid Leukemia Research, Chronic Myeloid Leukemia Treatments, Epigenetics and DNA Methylation, Chronic Lymphocytic Leukemia Research, and Childhood Cancer Survivors' Quality of Life.

Recent publications include the following papers:

  • Value of flow cytometry for MRD-based relapse prediction in B-cell precursor ALL in a multicenter setting (2020), published in Leukemia
  • Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia (2023), published in npj Precision Oncology
  • Is microchimerism a sign of imminent disease recurrence after allogeneic hematopoietic stem cell transplantation? A systematic review of the literature (2020), published in Blood Reviews
  • High CD34 surface expression in BCP-ALL predicts poor induction therapy response and is associated with altered expression of genes related to cell migration and adhesion (2022), published in Molecular Oncology
  • Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia (2023), published in bioRxiv (Cold Spring Harbor Laboratory)

Madsen's work has appeared frequently in the following publication venues:

  • Blood
  • Leukemia
  • npj Precision Oncology
  • Blood Reviews
  • Molecular Oncology

Frequent collaborators in Madsen's research include Hanne Vibeke Marquart, Kjeld Schmiegelow, Carsten Heilmann, Signe Modvig, and Ulrika Norén-Nyström. These collaborators have co-authored multiple papers covering various aspects of hematology and leukemia research.

Best Publications

  • Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein.

    H. O. Madsen;P. Garred;S. Thiel;J. A. L. Kurtzhals

  • Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data.

    V H J van der Velden;G Cazzaniga;A Schrauder;J Hancock

  • The MLL recombinome of acute leukemias in 2017

    C Meyer;T Burmeister;D Gröger;G Tsaur

  • A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein

    Hans O. Madsen;P. Garred;Joergen A. L. Kurtzhals;Lars U. Lamm

  • Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis

    Peter Garred;Tacjana Pressler;Hans O. Madsen;Birgitte Frederiksen

  • Acute respiratory tract infections and mannose-binding lectin insufficiency during early childhood.

    Anders Koch;Mads Melbye;Per Sørensen;Preben Homøe

  • Mannose-binding lectin and its genetic variants

    Peter Garred;F. Larsen;J. Seyfarth;Ricardo Fujita

  • Mannose-binding lectin deficiency--revisited

    Peter Garred;Flemming Larsen;Hans O Madsen;Claus Koch

  • Different Molecular Events Result in Low Protein Levels of Mannan-Binding Lectin in Populations from Southeast Africa and South America

    Madsen Ho;Satz Ml;Hogh B;Svejgaard A

  • Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin

    Peter Garred;Hans O Madsen;Ulla Balslev;Bo Hofmann

  • Results of NOPHO ALL2008 treatment for patients aged 1-45 years with acute lymphoblastic leukemia.

    N. Toft;N. Toft;H. Birgens;J. Abrahamsson;L. Griskevicius

  • Mannose-binding lectin engagement with late apoptotic and necrotic cells.

    Alma J. Nauta;Nicoline Raaschou‐Jensen;Anja Roos;Mohamed R. Daha

  • Increased frequency of homozygosity of abnormal mannan-binding-protein alleles in patients with suspected immunodeficiency

    P. Garred;H.O. Madsen;B. Hofmann;A. Svejgaard

  • Mannose-binding lectin polymorphisms and susceptibility to infection in systemic lupus erythematosus.

    Peter Garred;Hans O. Madsen;Poul Halberg;Jørgen Petersen

  • Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark.

    Merete Pedersen;Søren Jacobsen;Peter Garred;Hans O. Madsen

  • Association of mannose-binding lectin gene variation with disease severity and infections in a population-based cohort of systemic lupus erythematosus patients.

    P Garred;A Voss;H O Madsen;P Junker

  • Mannose-Binding Lectin Variant Alleles and the Risk of Arterial Thrombosis in Systemic Lupus Erythematosus

    Tommy Øhlenschlæger;Peter Garred;Hans O. Madsen;Søren Jacobsen

  • Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein.

    Flemming Larsen;Hans O. Madsen;Robert B. Sim;Claus Koch

  • Association of mannose-binding-lectin deficiency with severe atherosclerosis

    Hans O Madsen;Vibeke Videm;Arne Svejgaard;Jan L Svennevig

  • Immunodeficiency Associated with FCN3 Mutation and Ficolin-3 Deficiency

    Lea Munthe-Fog;Tina Hummelshøj;Christian Honoré;Hans O Madsen

  • Polymorphisms in the FCN2 gene determine serum variation and function of Ficolin-2

    Tina Hummelshoj;Lea Munthe-Fog;Hans O. Madsen;Teizo Fujita

Frequent Co-Authors

Peter Garred
Peter Garred University of Copenhagen
Lars P. Ryder
Lars P. Ryder University of Copenhagen
Kjeld Schmiegelow
Kjeld Schmiegelow University of Copenhagen
Arne Svejgaard
Arne Svejgaard University of Copenhagen
Henrik Hjalgrim
Henrik Hjalgrim Statens Serum Institut
Søren Jacobsen
Søren Jacobsen Copenhagen University Hospital
Claus Koch
Claus Koch University of Southern Denmark
Steffen Thiel
Steffen Thiel Aarhus University
Henning Bliddal
Henning Bliddal Copenhagen University Hospital
Niels Ødum
Niels Ødum University of Copenhagen

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